FLICKR, ABBYBATCHELDERCalifornia-based startup Natera this week (February 27) announced the launch of Panorama, a commercial test for chromosomal abnormalities with a sensitivity similar to riskier, more invasive methods, reported a Nature blog. The new test adds to a growing fleet of non-invasive genetic screens for pregnant women to detect chromosomal disorders in their unborn child. Performed on a drop of blood from the mother-to-be, the tests are a risk-free alternative to techniques like amniocentesis and chorionic villus sampling, both of which carry a risk of miscarriage.
Joining Verinata, Sequenom, and Ariosa, Natera is the fourth company to offer this type of product for women at high risk of having babies with Down’s syndrome and other genetic disorders. And with US health insurers such as Aetna and Wellpoint planning to cover the tests, the market could be worth billions.
Of the four tests currently available, Verinata’s verifi ($1,500) and Sequenom’s MaterniT21PLUS ($2,762) screen for the widest range of disorders, including those associated with and extra X or Y chromosome. Natera’s Panorama can detect a missing X chromosome but no other kind of sex chromosome irregularities, and costs $1,495. All of the tests, including Ariosa’s Harmony ($795), can identify a fetus with Down’s syndrome, caused by three copies of chromosome 21, more than ...
