whole genome sequencing

Comprehensive genome sequencing of 13,880 tumors revealed somatic and germline mutations that could influence patient treatment and prognosis.

A new antibiotic is the first to block a critical transport mechanism in drug-resistant bacteria.

This year’s stories highlight the expanding versatility of genetic techniques and the increasing utility of such research in all life science fields.

A high-quality reference genome for this vulnerable feline may help scientists understand why they’re so prone to transitional cell carcinoma in captivity.

A high school student uses crowdfunding to produce the first genome assembly for this popular aquarium species, underscoring the increasing feasibility of whole-genome sequencing.

Most differences in gene expression among cells within a tumor are likely due to environment or noise, a study suggests. 

Sequences for the model organism and two of its kin reveal how these plants got their oversized genomes.

A high-quality genome sequence for this versatile insect will likely aid eco-evolutionary research.

Most of the human induced pluripotent stem cells stored at major cell line repositories and used in research harbor thousands of DNA errors, a study finds, highlighting the need for improved quality control measures.

Height and onset of menarche are among traits linked to previously unidentified genetic variants in noncoding regions of the human genome.

A chromosome-scale genome sequence for this infamous agricultural pest could help mitigate its plagues.

Genetic studies have made it clear that eukaryotic horizontal gene transfer can and does happen. Exactly how, though, remains speculative.

DNA passed to and from all kinds of organisms, even across kingdoms, has helped shape the tree of life, to a large and undisputed degree in microbes and also unexpectedly in multicellular fungi, plants, and animals.