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Obesity Vaccine Success

A biotech company is developing a vaccine that promotes weight loss in mice.

Written byEdyta Zielinska
| 1 min read

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FLICKR CREATIVE COMMONS, :.[MELISSA]:.

Two obesity vaccines that target somatostatin, a hormone that can promote weight gain, were shown to reduce body weight of obese mice by 10 percent, according to a new study in the Journal of Animal Science and Biotechnology, an open-access publication.

The sole author on the paper, Keith Haffer from Braasch Biotech in South Dakota, injected mice fed an obesity-inducing diet with two vaccine candidates designed to produce antibodies against somatostatin. Reducing somatostatin levels is thought to help increase the amount of two other hormones—growth hormone and insulin-like growth factor—that promote weight loss.

“Although further studies are necessary to discover the long-term implications of these vaccines, treatment of human obesity with vaccination would provide physicians with a drug- and surgical- free option against the weight ...

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Meet the Author

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    Edyta Zielinska was a senior editor at The Scientist from 2007 to 2013, where she worked closely with scientific illustrators to develop accompanying graphics to illuminate complex concepts. 

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