“Out of Africa” Theory Gets the Genomic Treatment

A trio of genetic studies on seldom-studied indigenous populations points to a single wave of migration as humanity wandered from its evolutionary homeland into the rest of the world.

Written byBob Grant
| 2 min read

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WIKIMEDIA, EINSAMER SCHUTZEMost of the DNA detectable in the genomes of modern humans can be traced back to a single migration of Homo sapiens out of Africa millennia ago, according to three genomic studies published last week (September 21) in Nature. “I think all three studies are basically saying the same thing,” Joshua Akey of the University of Washington, who wrote a commentary accompanying the papers, told The New York Times. “We know there were multiple dispersals out of Africa, but we can trace our ancestry back to a single one.”

While the three papers—which present the genome sequences of 787 people—all conclude that the vast majority of the modern human genome owes to a single out-of-Africa migration event, they differ in estimating the timing of that movement.

University of Copenhagen geneticist Eske Willerslev led a team that sequenced the genomes of 83 Australian Aboriginal people and 25 Papua New Guineans. Mait Metspalu of the Estonian Biocentre led a massive group of researchers, which sequenced 483 genomes from people in Europe, Asia, Africa, and Australia. The third study, headed by Harvard’s David Reich, considered 300 genome sequences from people all over the globe.

Willerslev’s and Reich’s teams concluded that the migration event occurred between 80,000 and 50,000 years ago. Metspalu’s team, however, proposed an earlier migration—sometime ...

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Meet the Author

  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

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