Peanut Allergy Treatment Works Long Term

Four years after taking a probiotic and peanut protein for 18 months, two-thirds of children in a small clinical trial can eat peanuts with no health issues.

| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

FLICKR, AIRPIXIn 2013, researchers at Murdoch Children’s Research Institute in Australia dosed 48 children either with a probiotic with increasing amounts of a peanut protein, a treatment known as PPOIT, or with a placebo once daily for a year and a half. This week (August 15), they reported that some 70 percent of the participants who received PPOIT can ingest peanut-containing foods with no adverse reactions, according to a study published in The Lancet Child & Adolescent Health.

That result represents only a slight dip from the original results that found 82 percent of the treated children could tolerate peanuts one month after finishing their PPOIT courses, suggesting the treatment is the first long-lasting option for those who suffer from a peanut allergy.

“These children had been eating peanut freely in their diet without having to follow any particular program of peanut intake in the years after treatment was completed,” lead researcher Mimi Tang says in a statement sent to The Scientist. “This is a major step forward in identifying an effective treatment to address the food allergy problem in Western societies.”

The probiotic used was Lactobacillus rhamnosus, a bacterium that may help mitigate allergic symptoms. “The probiotic acts on the immune system, ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • Jef Akst

    Jef Akst was managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.
Share
A greyscale image of cells dividing.
March 2025, Issue 1

How Do Embryos Know How Fast to Develop

In mammals, intracellular clocks begin to tick within days of fertilization.

View this Issue
Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

Integra Logo
3D rendered cross section of influenza viruses, showing surface proteins on the outside and single stranded RNA inside the virus

Genetic Insights Break Infectious Pathogen Barriers

Thermo Fisher Logo
A photo of sample storage boxes in an ultra-low temperature freezer.

Navigating Cold Storage Solutions

PHCbi logo 
The Immunology of the Brain

The Immunology of the Brain

Products

Sapio Sciences

Sapio Sciences Makes AI-Native Drug Discovery Seamless with NVIDIA BioNeMo

DeNovix Logo

New DeNovix Helium Nano Volume Spectrophotometer

Olink Logo

Olink® Reveal: Accessible NGS-based proteomics for every lab

Olink logo
Zymo Logo

Zymo Research Launches the Quick-16S™ Full-Length Library Prep Kit