Pfizer’s COVID-19 Vaccine Reduces Viral Load: Study

Preliminary results from an Israel-based study suggest that one dose of the vaccine reduces infectiousness—a key factor in slowing virus spread.

asher jones
| 2 min read
Pfizer, SARS-CoV-2, COVID-19, pandemic, coronavirus, vaccine, vaccination, Israel, B.1.1.7, B.1.351, variant, disease

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

ABOVE: © ISTOCK, ALEXANDROS MICHAILIDIS

People who became infected with SARS-CoV-2 after receiving one dose of Pfizer’s COVID-19 vaccine harbored about four times less virus than did unvaccinated people who caught the virus, according to preliminary results posted to the preprint server medRxiv on February 8.

Several COVID-19 vaccines, including Pfizer’s version, are about 95 percent effective in preventing disease. But there’s less known about whether vaccinated individuals can still transmit the SARS-CoV-2 virus to others.

In the study, which has not yet undergone peer review, researchers in Israel measured the viral loads in 2,897 unvaccinated people and in 2,897 age- and sex-matched people who had received their first of two doses of the Pfizer vaccine. The authors conclude in their report that “viral load is reduced 4-fold for infections occurring 12–28 days after the first dose of vaccine. These reduced viral loads hint to lower infectiousness, further contributing to ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • asher jones

    Asher Jones

    Asher is a former editorial intern at The Scientist. She completed a PhD in entomology from Penn State University, and she was a 2020 AAAS Mass Media Fellow at Voice of America. You can find more of her work here.

Share
A greyscale image of cells dividing.
March 2025, Issue 1

How Do Embryos Know How Fast to Develop

In mammals, intracellular clocks begin to tick within days of fertilization.

View this Issue
Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

Integra Logo
3D rendered cross section of influenza viruses, showing surface proteins on the outside and single stranded RNA inside the virus

Genetic Insights Break Infectious Pathogen Barriers

Thermo Fisher Logo
A photo of sample storage boxes in an ultra-low temperature freezer.

Navigating Cold Storage Solutions

PHCbi logo 
The Immunology of the Brain

The Immunology of the Brain

Products

Sapio Sciences

Sapio Sciences Makes AI-Native Drug Discovery Seamless with NVIDIA BioNeMo

DeNovix Logo

New DeNovix Helium Nano Volume Spectrophotometer

Olink Logo

Olink® Reveal: Accessible NGS-based proteomics for every lab

Olink logo
Zymo Logo

Zymo Research Launches the Quick-16S™ Full-Length Library Prep Kit