Pfizer’s COVID-19 Vaccine Reduces Viral Load: Study

Preliminary results from an Israel-based study suggest that one dose of the vaccine reduces infectiousness—a key factor in slowing virus spread.

Written byAsher Jones
| 2 min read
Pfizer, SARS-CoV-2, COVID-19, pandemic, coronavirus, vaccine, vaccination, Israel, B.1.1.7, B.1.351, variant, disease

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ABOVE: © ISTOCK, ALEXANDROS MICHAILIDIS

People who became infected with SARS-CoV-2 after receiving one dose of Pfizer’s COVID-19 vaccine harbored about four times less virus than did unvaccinated people who caught the virus, according to preliminary results posted to the preprint server medRxiv on February 8.

Several COVID-19 vaccines, including Pfizer’s version, are about 95 percent effective in preventing disease. But there’s less known about whether vaccinated individuals can still transmit the SARS-CoV-2 virus to others.

In the study, which has not yet undergone peer review, researchers in Israel measured the viral loads in 2,897 unvaccinated people and in 2,897 age- and sex-matched people who had received their first of two doses of the Pfizer vaccine. The authors conclude in their report that “viral load is reduced 4-fold for infections occurring 12–28 days after the first dose of vaccine. These reduced viral loads hint to lower infectiousness, further contributing to ...

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