Plant RNAs Found in Mammals

MicroRNAs from plants accumulate in mammalian blood and tissues, where they can regulate gene expression.

Written byCristina Luiggi
| 3 min read

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MicroRNAs from common plant crops such as rice and cabbage can be found in the blood and tissues of humans and other plant-eating mammals, according to a study published today in Cell Research. One microRNA in particular, MIR168a, which is highly enriched in rice, was found to inhibit a protein that helps removes low-density lipoprotein (LDL) from the blood, suggesting that microRNAs can influence gene expression across kingdoms.

“This is a very exciting piece of work that suggests that the food we eat may directly regulate gene expression in our bodies,” said Clay Marsh, Director of the Center for Personalized Health Care at the Ohio State University College of Medicine who researches microRNA expression in human blood but who was not involved in the study.

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