A Hawaiian bobtail squid (Euprymna scolopes) rests on a reflective surface
Reshuffled Genomes May Explain Cephalopods’ Smarts
In two related studies, researchers describe huge chromosomal rearrangements and about 500 novel gene clusters in the octopus, squid, and cuttlefish genomes, which they say could help explain how they evolved their extraordinary brains.
ABOVE: TOM KLEINDINST
Reshuffled Genomes May Explain Cephalopods’ Smarts
Reshuffled Genomes May Explain Cephalopods’ Smarts

In two related studies, researchers describe huge chromosomal rearrangements and about 500 novel gene clusters in the octopus, squid, and cuttlefish genomes, which they say could help explain how they evolved their extraordinary brains.

In two related studies, researchers describe huge chromosomal rearrangements and about 500 novel gene clusters in the octopus, squid, and cuttlefish genomes, which they say could help explain how they evolved their extraordinary brains.

ABOVE: TOM KLEINDINST

gene expression

Senior woman wearing a grey pullover sitting on a bed and holding her back.
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Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.
An illustration showing a scale weighing two double-stranded pieces of DNA that has a big question mark in the center.
Mouse Foraging Behavior Shaped by Opposite-Sex Parent’s Genes
Dan Robitzski | Apr 12, 2022
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The Scientist Creative Services Team, Resolve Biosciences | Apr 12, 2022
How to visualize gene expression patterns in situ
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Jef Akst | Apr 4, 2022
A handful of new studies moves the needle toward a consensus on the long-disputed question of whether insect wings evolved from legs or from the body wall, but the devil is in the details.
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Virus Alters Caterpillars’ Vision to Trick Them into Climbing
Alejandra Manjarrez | Mar 25, 2022
A study finds that a baculovirus that infects cotton bollworm larvae changes the expression of genes involved in light perception, driving them to seek heights that could favor viral transmission.
Female reproductive System Anatomy stock photo
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Roni Dengler, PhD | Apr 8, 2022
Rounds of trial-and-error exploring the layer of cells covering the ovary leave open questions about stem cells that are associated with ovarian cancer.
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Antibiotics Given to Moths Spur Upregulation of Growth Genes
Devin A. Reese | Mar 1, 2022
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illustration of a large purple molecular complex with a strand of orange RNA running through it and red strand emerging from it
Study Reveals Outsize Role of mRNA Region in Tuning Expression
Sophie Fessl | Jan 27, 2022
A new method helps researchers uncover the rules of ribosome recruitment in yeast.
Technique Talk: Single-Cell Sequencing Experimental Design
Technique Talk: Single-Cell Sequencing Experimental Design
The Scientist Creative Services Team | Dec 21, 2021
Learn how to balance sample limitations and experimental methods for optimal single-cell sequencing results.
An electron microscopy image of a cell with the nucleolus shown in blue, chromatin in green, and nuclear envelope in red
Aging in Mice Linked to Misexpression of Class of Genes
Sophie Fessl | Dec 21, 2021
Genes lacking a particular structure known as CpG islands tend to go haywire in older cells, a study finds, potentially contributing to key facets of aging. But it’s not yet clear if the relationship is causal.
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Chloe Tenn | Dec 9, 2021
A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.
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Conceptual image of gene expression in DNA
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Jack J. Lee | Nov 1, 2021
Certain stretches of DNA that regulate gene expression have evolved differently from protein-coding genes.
SYNGAP1 helps neurons eliminate old synapses and form new ones after a novel experience (left and center left)—a process weakened in mice missing a copy of the gene (center right and right).
Autism-Linked Gene SYNGAP1 Molds Synaptic Plasticity, Learning
Angie Voyles Askham | Oct 26, 2021
The finding may help to explain why people with SYNGAP1 mutations tend to have learning difficulties and a high tolerance for pain.
Discover how to scale up cellular assays during drug discovery
High-Throughput Solutions for Lead Candidate Discovery
The Scientist Creative Services Team, Thermo Fisher Scientific | Oct 18, 2021
New technologies allow researchers to scale up assays for cellular functions.
A view of the nucleus of a cell with DNA in blue, RNA in pink, and associated proteins in yellow and purple
DNA Methylation Influences Replication and Genome Organization
Abby Olena | Sep 22, 2021
A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication.
Abstract illustration of DNA
Signaling Dynamics Fine-Tune Gene Expression
Ruth Williams | Sep 3, 2021
The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.
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Technique Talk: Designing and Optimizing RNA-seq Experiments
The Scientist Creative Services Team | Aug 31, 2021
Learn how to select and perfect RNA-seq technologies to answer specific research questions.  
A medical linear accelerator used to deliver radiation therapy
Tool Would Use Tumor Gene Expression to Inform Radiation Dose
Alejandra Manjarrez | Aug 27, 2021
In a retrospective analysis, a team found that an algorithm integrating the gene expression of a tumor with the radiation dose a patient received predicted how well the patient responded to the treatment.