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Single cells rendered in 3D
Capturing Complexity Cell by Cell
With the help of single-cell sequencing, researchers characterize biological complexity more fully across a multitude of applications.
Capturing Complexity Cell by Cell
Capturing Complexity Cell by Cell

With the help of single-cell sequencing, researchers characterize biological complexity more fully across a multitude of applications.

With the help of single-cell sequencing, researchers characterize biological complexity more fully across a multitude of applications.

gene expression

Solving Sample Preparation Challenges Across Diverse Tissue Types
Solving Sample Preparation Challenges Across Diverse Tissue Types
The Scientist Staff | Nov 11, 2024 | 1 min read
In this webinar, Caleb Proctor will tackle nucleic acid extraction complexities, sharing a streamlined pathway for obtaining high-quality and high-quantity results.
A baby rhesus macaque against a forest backdrop.
White Blood Cells, Hurricanes, and the Monkeys of Cayo Santiago
Hannah Thomasy, PhD | Oct 1, 2024 | 2 min read
Citizen scientists help monitor monkey immune cells, providing a foundation for future work on stress, sociality, and aging.
Spying on the Enemy: Using Bacteria to Fight Antibiotic Resistance
Spying on the Enemy: Using Bacteria to Fight Antibiotic Resistance
The Scientist Staff | Sep 6, 2024 | 1 min read
Discover how scientists engineer systems constructed from bacterial components to investigate and combat antimicrobial resistance.
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Harnessing Molecular Farming’s Potential
Priyom Bose, PhD | Sep 5, 2024 | 8 min read
Molecular farming is a promising technique that enables the production of biopharmaceuticals and other high value compounds in plants.
Discover What Digital PCR Can Do Across a Wide Range of Applications
Digital PCR Applications
Thermo Fisher Scientific | Jul 9, 2024 | 1 min read
Digital PCR is highly sensitive and precise, making it ideal for detecting rare targets and measuring small-fold changes.
Image of a stem cell and DNA against a light background.
Using Genetic Cartography to Map Cell Lineage
Laura Tran, PhD | May 17, 2024 | 4 min read
By coupling cell lineage tracking with molecular gene expression patterns, researchers deciphered how gene activity influences immune cell production.
Two drawn heads on a blue background with gears in their heads. A red spot on two gears is magnified over one head.
Biological Sex Influences Brain Protein Expression
Shelby Bradford, PhD | Apr 4, 2024 | 3 min read
Neurological disorders often have sex biases, and these differences could be due to altered protein expression in the brain.
A DNA sequence represented by its base letters.
Measuring the Genome and Methylome at Single Base Resolution
biomodal | Mar 14, 2024 | 1 min read
Researchers can build models to predict gene expression by detecting and differentiating between cytosine methylation and hydroxymethylation marks in the genome.
Researchers can obtain epigenetic information in addition to genetic insights from a single DNA sample.
The Six-Base Genome Reveals Multimodal Data from a Single DNA Sample
The Scientist and biomodal | Mar 12, 2024 | 4 min read
To gather multiomic insights, researchers used to combine data from multiple workflows, but duet evoC provides more information from less sample in one workflow.
Novelty Activates a Long Noncoding RNA for Spatial Learning in Mice
Shelby Bradford, PhD | Feb 6, 2024 | 4 min read
Genes activated in new environments include those used during development.
A scientist loads a 96-well plate containing qPCR reactions into a thermal cycler for DNA amplification and detection.
Insights into qPCR: Protocol, Detection Methods, and Analysis
Tanuka Biswas, PhD | Nov 8, 2023 | 6 min read
Learn about quantitative PCR (qPCR), including its fundamentals, common applications, modes of detection, and key quantification methods.
Plant (<em >Arabidopsis thaliana</em>) root tips analyzed with PHYTOMap.
Illuminating the Plant Gene Map
Laura Tran, PhD | Nov 2, 2023 | 4 min read
PHYTOMap revealed the intricate genetic plant landscape, which helped researchers better understand how cells and gene expression influence each other in three-dimensional space.
Professor Alexandra Whiteley and graduate student Autumn Matthews look at an image of a western blot on their laboratory computer.
An Ancient Viral Protein May Play a Key Role in ALS
Aditi Subramaniam, PhD | Aug 15, 2023 | 4 min read
Researchers find that UBQLN2 gene dysfunction causes a virus-like protein to accumulate in cells, which changes gene expression and may contribute to disease progression in amyotrophic lateral sclerosis (ALS).
Tumor microenvironment concept with cancer cells
Cancers Protect Themselves Against Their Own Mutations
Ida Emilie Steinmark, PhD | Aug 1, 2023 | 2 min read
Tumors overexpress certain genes to survive a growing pile of harmful mutations, a trait that scientists could exploit to target with drugs.
Composition of DNA with a glitch effect
“Silent” Mutations Make Noise In Cancer
Katarina Zimmer | May 1, 2023 | 10+ min read
Synonymous mutations have long been ignored in cancer studies since they don’t affect the amino acid sequences of proteins. But research increasingly reveals that they can have disease-driving effects.
Histology showing IL-6 expression
Immune Molecule Alters Cellular Makeup of Human Brain Organoids
Charles Q. Choi, Spectrum | Apr 17, 2023 | 4 min read
The changes may help explain the link between maternal infection and autism, though more research is needed.
Artist&rsquo;s rendition of orange DNA coiled around a blue histone protein.
“Cryptic Transcription”: How Aging Cells Express Fragments of Genes
Kamal Nahas, PhD | Apr 6, 2023 | 4 min read
Aging cells with weakened gene regulation spuriously transcribe RNAs, but their impact on health and longevity still needs to be examined.
Headshots of three people smiling and looking at camera.
2023 Brain Prize Awarded for Research on Synaptic Plasticity
Natalia Mesa, PhD | Mar 23, 2023 | 3 min read
The Lundbeck Foundation announces an international cohort of neuroscientists have collectively won the €1.3 million Brain Prize.
The face of a young woman and the face of an old man surrounded by mechanical clocks.
Daily Gene Expression Rhythms Vary with Sex and Age: Study
Alejandra Manjarrez, PhD | Feb 2, 2023 | 3 min read
By studying tissues from deceased people, a team found that women have more rhythmical gene expression and that this molecular rhythmicity decreases with age.
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