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Coronal section of a brain
Immunity-Linked Genes Expressed Differently in Brains of Autistic People
Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.
Immunity-Linked Genes Expressed Differently in Brains of Autistic People
Immunity-Linked Genes Expressed Differently in Brains of Autistic People

Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.

Data from postmortem brain tissues adds to the evidence that inflammation is associated with autism.

gene expression
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist Staff | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Cells with miRNA activity reporter glowing
MicroRNAs Can Boost Gene Expression: Study
Holly Barker | Nov 15, 2022 | 3 min read
The tiny strings of RNA promote translation of a protein implicated in cancer, a hint they could regulate gene expression in more ways than previously thought.
Sartorius
Understanding the Blood Cancer Genomic Landscape 
The Scientist Creative Services Team | 1 min read
Information about the genomic and immunological characteristics of blood cancers is helping scientists discover and develop new immunotherapies.
A closeup of a dead frog floating in water with aquatic plants underneath it
Chytrid Fungus Deploys Varying Strategies to Infect Amphibians
Tess Joosse | Nov 14, 2022 | 2 min read
The ability to activate different sets of genes has likely helped the chytrid fungus Batrachochytrium dendrobatidis spread widely in amphibians, resulting in global population declines. 
Illustration of a human and Neanderthal skull side by side.
Mutation Linked to Difference Between Human and Neanderthal Brains
Dan Robitzski | Sep 9, 2022 | 5 min read
A single amino acid substitution in a protein causes increased neuron production in the frontal lobes of humans compared to Neanderthals—a tiny difference that could have given our species a cognitive edge, researchers say.
VAI
One Sequence, Many Variations
Van Andel Institute | 5 min read
Andrew Pospisilik explores the epigenetic changes that give organisms the plasticity to change in response to their environments.
illustration of brain with DNA strand coming out the top
Genetic Underpinnings of Brain Activity May Differ in Autism
Emily Harris, Spectrum | Jul 19, 2022 | 3 min read
A study finds that expression levels of certain genes that track with brain activity—particularly those involved in brain development—vary between people with autism and their non-autistic peers.
Ribonucleic acid strands consisting of nucleotides important for protein bio-synthesis
Katharina Höfer Probes the Machinery of Bacterial Gene Expression
Hannah Thomasy | Jun 13, 2022 | 3 min read
The molecular biologist studies how chemical modifications to RNA building blocks change the way RNA regulates complex cellular processes.
VAI
Exposed: Environmental Echoes in Health - A Special Podcast Series
The Scientist Creative Services Team and Van Andel Institute | 2 min read
Epigenetic experts discuss how environment and diet leave lasting impressions on the human genome.
a Hawaiian bobtail squid (Euprymna scolopes) resting on a reflective surface
Reshuffled Genomes May Explain Cephalopods’ Smarts
Sophie Fessl, PhD | May 13, 2022 | 4 min read
In two related studies, researchers describe huge chromosomal rearrangements and about 500 novel gene clusters in the octopus, squid, and cuttlefish genomes, which they say could help explain how they evolved their extraordinary brains.
Senior woman wearing a grey pullover sitting on a bed and holding her back.
Early Inflammation Protects Against Chronic Pain, Study Finds
Alejandra Manjarrez, PhD | May 12, 2022 | 3 min read
Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.
Discover how to Select and Design qPCR Probes
Selecting Probes That Rise to Any qPCR Challenge
The Scientist Creative Services Team and LGC Biosearch Technologies | 1 min read
Learn how to select qPCR probes that match downstream applications.
An illustration showing a scale weighing two double-stranded pieces of DNA that has a big question mark in the center.
Mouse Foraging Behavior Shaped by Opposite-Sex Parent’s Genes
Dan Robitzski | Apr 12, 2022 | 7 min read
A study in mice finds that for certain genes, one parent’s allele can dominate expression and shape behavior—and which parent’s allele does so varies throughout the body.
Close up photo of a wing
Unearthing the Evolutionary Origins of Insect Wings
Jef Akst | Apr 4, 2022 | 6 min read
A handful of new studies moves the needle toward a consensus on the long-disputed question of whether insect wings evolved from legs or from the body wall, but the devil is in the details.
Smarter Sample Prep for Improved Single-Cell Sequencing
Smarter Sample Prep for Single-Cell Sequencing
The Scientist Creative Services Team and Miltenyi Biotec | 1 min read
In this webinar, Carina Emery will discuss tissue dissociation techniques that lead to high-quality sequencing results.
Yellow and black caterpillar crawling on a leaf in a green background
Virus Alters Caterpillars’ Vision to Trick Them into Climbing
Alejandra Manjarrez, PhD | Mar 25, 2022 | 4 min read
A study finds that a baculovirus that infects cotton bollworm larvae changes the expression of genes involved in light perception, driving them to seek heights that could favor viral transmission.
Photo of a tiger moth
Antibiotics Given to Moths Spur Upregulation of Growth Genes
Devin A. Reese, PhD | Mar 1, 2022 | 2 min read
A new study has identified a molecular tradeoff between growth and immunity in moths in response to the administration of subtherapeutic doses of antibiotics, a common practice in animal husbandry.
Optimizing Reproducibility in Flow Cytometry
Beckman Coulter Life Sciences | 1 min read
Explore real solutions for single cell research.
illustration of a large purple molecular complex with a strand of orange RNA running through it and red strand emerging from it
Study Reveals Outsize Role of mRNA Region in Tuning Expression
Sophie Fessl, PhD | Jan 27, 2022 | 3 min read
A new method helps researchers uncover the rules of ribosome recruitment in yeast.
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