Illustration of a human and Neanderthal skull side by side.
Mutation Linked to Difference Between Human and Neanderthal Brains
A single amino acid substitution in a protein causes increased neuron production in the frontal lobes of humans compared to Neanderthals—a tiny difference that could have given our species a cognitive edge, researchers say.
Mutation Linked to Difference Between Human and Neanderthal Brains
Mutation Linked to Difference Between Human and Neanderthal Brains

A single amino acid substitution in a protein causes increased neuron production in the frontal lobes of humans compared to Neanderthals—a tiny difference that could have given our species a cognitive edge, researchers say.

A single amino acid substitution in a protein causes increased neuron production in the frontal lobes of humans compared to Neanderthals—a tiny difference that could have given our species a cognitive edge, researchers say.

gene expression
illustration of brain with DNA strand coming out the top
Genetic Underpinnings of Brain Activity May Differ in Autism
Emily Harris, Spectrum | Jul 19, 2022
A study finds that expression levels of certain genes that track with brain activity—particularly those involved in brain development—vary between people with autism and their non-autistic peers.
Ribonucleic acid strands consisting of nucleotides important for protein bio-synthesis
Katharina Höfer Probes the Machinery of Bacterial Gene Expression
Hannah Thomasy | Jun 13, 2022
The molecular biologist studies how chemical modifications to RNA building blocks change the way RNA regulates complex cellular processes.
VAI
Exposed: Environmental Echoes in Health - A Special Podcast Series
The Scientist Creative Services Team and Van Andel Institute
Epigenetic experts discuss how environment and diet leave lasting impressions on the human genome.
a Hawaiian bobtail squid (Euprymna scolopes) resting on a reflective surface
Reshuffled Genomes May Explain Cephalopods’ Smarts
Sophie Fessl | May 13, 2022
In two related studies, researchers describe huge chromosomal rearrangements and about 500 novel gene clusters in the octopus, squid, and cuttlefish genomes, which they say could help explain how they evolved their extraordinary brains.
Senior woman wearing a grey pullover sitting on a bed and holding her back.
Early Inflammation Protects Against Chronic Pain, Study Finds
Alejandra Manjarrez | May 12, 2022
Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.
Discover how to Select and Design qPCR Probes
Selecting Probes That Rise to Any qPCR Challenge
The Scientist Creative Services Team and LGC Biosearch Technologies
Learn how to select qPCR probes that match downstream applications.
An illustration showing a scale weighing two double-stranded pieces of DNA that has a big question mark in the center.
Mouse Foraging Behavior Shaped by Opposite-Sex Parent’s Genes
Dan Robitzski | Apr 12, 2022
A study in mice finds that for certain genes, one parent’s allele can dominate expression and shape behavior—and which parent’s allele does so varies throughout the body.
Close up photo of a wing
Unearthing the Evolutionary Origins of Insect Wings
Jef Akst | Apr 4, 2022
A handful of new studies moves the needle toward a consensus on the long-disputed question of whether insect wings evolved from legs or from the body wall, but the devil is in the details.
Smarter Sample Prep for Improved Single-Cell Sequencing
Smarter Sample Prep for Single-Cell Sequencing
The Scientist Creative Services Team and Miltenyi Biotec
In this webinar, Carina Emery will discuss tissue dissociation techniques that lead to high-quality sequencing results.
Yellow and black caterpillar crawling on a leaf in a green background
Virus Alters Caterpillars’ Vision to Trick Them into Climbing
Alejandra Manjarrez | Mar 25, 2022
A study finds that a baculovirus that infects cotton bollworm larvae changes the expression of genes involved in light perception, driving them to seek heights that could favor viral transmission.
Photo of a tiger moth
Antibiotics Given to Moths Spur Upregulation of Growth Genes
Devin A. Reese | Mar 1, 2022
A new study has identified a molecular tradeoff between growth and immunity in moths in response to the administration of subtherapeutic doses of antibiotics, a common practice in animal husbandry.
Optimizing Reproducibility in Flow Cytometry
Beckman Coulter Life Sciences
Explore real solutions for single cell research.
illustration of a large purple molecular complex with a strand of orange RNA running through it and red strand emerging from it
Study Reveals Outsize Role of mRNA Region in Tuning Expression
Sophie Fessl | Jan 27, 2022
A new method helps researchers uncover the rules of ribosome recruitment in yeast.
An electron microscopy image of a cell with the nucleolus shown in blue, chromatin in green, and nuclear envelope in red
Aging in Mice Linked to Misexpression of Class of Genes
Sophie Fessl | Dec 21, 2021
Genes lacking a particular structure known as CpG islands tend to go haywire in older cells, a study finds, potentially contributing to key facets of aging. But it’s not yet clear if the relationship is causal.
Visualize Transcript Location with Spatial Biology Techniques
Unraveling the Cellular and Subcellular Landscape Using Spatial Biology
The Scientist Creative Services Team and Resolve Biosciences
How to visualize gene expression patterns in situ
mice on wheel and ground
Exercise-Associated Protein Boosts Brain Function in Mice
Chloe Tenn | Dec 9, 2021
A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.
Conceptual image of gene expression in DNA
Enhancers: Conserved in Activity, Not in Sequence
Jack J. Lee | Nov 1, 2021
Certain stretches of DNA that regulate gene expression have evolved differently from protein-coding genes.
Female reproductive System Anatomy stock photo
Cells in the Ovary are Responsive Shape-Shifters
Roni Dengler, PhD
Rounds of trial-and-error exploring the layer of cells covering the ovary leave open questions about stem cells that are associated with ovarian cancer.
SYNGAP1 helps neurons eliminate old synapses and form new ones after a novel experience (left and center left)—a process weakened in mice missing a copy of the gene (center right and right).
Autism-Linked Gene SYNGAP1 Molds Synaptic Plasticity, Learning
Angie Voyles Askham, Spectrum | Oct 26, 2021
The finding may help to explain why people with SYNGAP1 mutations tend to have learning difficulties and a high tolerance for pain.