Remdesivir Shows Promise in Largest of Several Clinical Trials

Gilead’s experimental antiviral drug shortened the average time it took COVID-19 patients to recover in a NIAID-sponsored trial. There was weak evidence that it also helped reduce deaths.

| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

ABOVE: © ISTOCK.COM, KWANGMOOZAA

Remdesivir, an experimental antiviral drug developed by Gilead Sciences as a treatment for Ebola, has shown clinical benefit in a US clinical trial with 1,063 COVID-19 patients. While hospitalized COVID-19 patients receiving a placebo took an average of 15 days to recover from the disease, patients taking remdesivir recovered in an average of 11 days—a reduction of 31 percent.

“Remdesivir was better than placebo from the perspective of the primary endpoint, time to recovery,” reads a statement posted yesterday (April 29) by the National Institute of Allergy and Infectious Disease (NIAID). “More detailed information about the trial results, including more comprehensive data, will be available in a forthcoming report.”

The study did not conclusively demonstrate that the drug reduces mortality from COVID-19, although the NIAID statement noted that statistically insignificant results from the trial were suggestive of a survival benefit: the group receiving the drug had ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
A greyscale image of cells dividing.
March 2025, Issue 1

How Do Embryos Know How Fast to Develop

In mammals, intracellular clocks begin to tick within days of fertilization.

View this Issue
Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

Integra Logo
3D rendered cross section of influenza viruses, showing surface proteins on the outside and single stranded RNA inside the virus

Genetic Insights Break Infectious Pathogen Barriers

Thermo Fisher Logo
A photo of sample storage boxes in an ultra-low temperature freezer.

Navigating Cold Storage Solutions

PHCbi logo 
The Immunology of the Brain

The Immunology of the Brain

Products

Zymo Logo

Zymo Research Launches the Quick-16S™ Full-Length Library Prep Kit

BIOVECTRA

BIOVECTRA is Honored with 2025 CDMO Leadership Award for Biologics

Sino Logo

Gilead’s Capsid Revolution Meets Our Capsid Solutions: Sino Biological – Engineering the Tools to Outsmart HIV

Stirling Ultracold

Meet the Upright ULT Built for Faster Recovery - Stirling VAULT100™

Stirling Ultracold logo