Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies
Pharma Looks to Inflammasome Inhibitors as All-Around Therapies

Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.

Many major biopharmaceutical companies are developing or acquiring drugs that target the NLRP3 inflammasome, a large intracellular complex that researchers say can spark inflammation and stoke diseases of lifestyle and aging.

clinical research
Mary Jeanne Kreek, Methadone Developer, Dies at 84
Mary Jeanne Kreek, Methadone Developer, Dies at 84
Asher Jones | Mar 31, 2021
A physician and neurobiologist at the Rockefeller University who specialized in addiction research, Kreek was best known for her work on developing the treatment for heroin addiction.
Modeling the Human Lung with Organoids
Modeling the Human Lung with Organoids
The Scientist Creative Services Team in collaboration with MilliporeSigma | Mar 29, 2021
A new specialized cell culture media system generates induced pluripotent stem cell-derived lung organoids that more closely resemble the diversity of cell types found in the human lung.
AstraZeneca’s COVID-19 Shot Completely Prevented Severe Disease
AstraZeneca’s COVID-19 Shot Completely Prevented Severe Disease
Kerry Grens | Mar 22, 2021
The vaccine was 79 percent effective at blocking symptomatic infections, according to data from a Phase 3 trial in the US, Chile, and Peru. A US safety oversight board says the data might be incomplete.
José Baselga, Renowned Oncologist, Dies at 61
José Baselga, Renowned Oncologist, Dies at 61
Asher Jones | Mar 22, 2021
The cancer researcher and executive vice president of AstraZeneca’s oncology research and development is well known for his role in the development of pivotal breast cancer therapies.
A Global Registry Aims to See if COVID-19 Causes Diabetes
A Global Registry Aims to See if COVID-19 Causes Diabetes
Asher Jones | Mar 19, 2021
Researchers have collected hundreds of COVID-19–related diabetes case reports since August of last year, in hopes of teasing apart the complex links between the two diseases.
Eli Lilly Claims New Drug Can Slow Alzheimer’s-Related Decline
Eli Lilly Claims New Drug Can Slow Alzheimer’s-Related Decline
Lisa Winter | Mar 16, 2021
Patients who received the drug fared better cognitively and functionally than those taking placebo, but still experienced losses in performance.
Oxford/AstraZeneca COVID-19 Vaccine on Hold in Some Countries
Oxford/AstraZeneca COVID-19 Vaccine on Hold in Some Countries
Asher Jones | Mar 12, 2021
Rollouts of the shot have ground to a halt following reports of blood clots, but health authorities say that these fears are unfounded and vaccination programs should continue.
COVID-19 Vaccine Combos Aim to Boost Immunity
COVID-19 Vaccine Combos Aim to Boost Immunity
Asher Jones | Mar 9, 2021
Mix-and-match shots could simplify vaccine rollout and stimulate more-robust immune responses. Ongoing clinical trials will soon give answers.
NIH Halts Outpatient COVID-19 Convalescent Plasma Trial
NIH Halts Outpatient COVID-19 Convalescent Plasma Trial
Marcus A. Banks | Mar 4, 2021
The decision adds to evidence that the benefits of plasma infusions from COVID-19 survivors may be limited, but advocates say the case isn’t closed.