Found: A Cancer Drug’s Mechanism of Action
Found: A Cancer Drug’s Mechanism of Action
As ONC201 moves through human clinical trials, scientists finally figure out that the compound and its analogs target a mitochondrial protease.
Found: A Cancer Drug’s Mechanism of Action
Found: A Cancer Drug’s Mechanism of Action

As ONC201 moves through human clinical trials, scientists finally figure out that the compound and its analogs target a mitochondrial protease.

As ONC201 moves through human clinical trials, scientists finally figure out that the compound and its analogs target a mitochondrial protease.

clinical research
AI Accurately Detects Lung Cancer in Scans
AI Accurately Detects Lung Cancer in Scans
Shawna Williams | May 21, 2019
An artificial intelligence program called a neural network exceeds radiologists’ ability to detect malignancies, but more testing is needed before using the program clinically.
Study: Antibiotics After Assisted Birth Reduce Maternal Infections
Study: Antibiotics After Assisted Birth Reduce Maternal Infections
Ashley P. Taylor | May 14, 2019
Delivery guidelines should be updated to reflect these results, the authors write.
Donor-Derived iPS Cells Show Promise for Treating Eye Disease
Donor-Derived iPS Cells Show Promise for Treating Eye Disease
Jef Akst | Apr 30, 2019
Age-related macular degeneration patients who received injections of retinal cells derived from donors’ induced pluripotent stem cells have maintained their level of eyesight for a year.
Peanut Allergy Immunotherapy Increases Anaphylaxis Risk: Study
Peanut Allergy Immunotherapy Increases Anaphylaxis Risk: Study
Kerry Grens | Apr 26, 2019
Although the oral treatment seems to work, an analysis of the results from 12 clinical trials finds kids who got an immunotherapy have a greater rate of serious reactions.
A Revised CAR T for Lymphoma Has Fewer Side Effects
A Revised CAR T for Lymphoma Has Fewer Side Effects
Kerry Grens | Apr 23, 2019
An early-stage clinical study finds that none of the 25 patients treated developed neurotoxicity or cytokine release syndrome, common hazards of the cancer immunotherapy.
Q&A: A 10,000-Genome Milestone for Shared Pediatric Cancer Data  
Q&A: A 10,000-Genome Milestone for Shared Pediatric Cancer Data  
Carolyn Wilke | Apr 1, 2019
Computational biologist Jinghui Zhang of St. Jude realized scientists could work more efficiently with tools and genomic data shared on the cloud.
Tuberculosis Can Emerge After Cancer Immunotherapy
Tuberculosis Can Emerge After Cancer Immunotherapy
Ashley Yeager | Apr 1, 2019
At least a handful of patients have developed active TB after receiving cancer treatment designed to boost the immune system’s antitumor response.
Image of the Day: Wiggles and Squirms
Image of the Day: Wiggles and Squirms
Carolyn Wilke | Mar 29, 2019
An artificially intelligent program tracks the motion of infants to help doctors look for links to disorders with abnormal motions.
<em>The Lancet</em> Retracts Cardiac Stem Cell Clinical Trial Paper
The Lancet Retracts Cardiac Stem Cell Clinical Trial Paper
Kerry Grens | Mar 14, 2019
The publication of the SCIPIO trial is among many by Piero Anversa’s lab that Harvard Medical School flagged for fraudulent data.