Scientists Voice Concerns over Russian COVID-19 Vaccine Study

Almost 40 scientists have signed an open letter, citing odd patterns in the data and a lack of transparency after authors withheld the full data.

amanda heidt
| 3 min read
COVID-19, SARS-CoV-2, coronavirus, pandemic, Russia, vaccine, clinical trial, data, ethics, adenovirus, spike protein, Lancet

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ABOVE: The Russian vaccine relies on a human adenovirus to prime the body’s immune response to SARS-CoV-2.
© ISTOCK.COM, CHRISTOPH BURGSTEDT

The first data detailing Russia’s COVID-19 vaccine—nicknamed Sputnik—was published last week (September 4) in The Lancet. Almost immediately, other scientists began to call attention to unlikely patterns in the data, asking for raw numbers to verify the study’s conclusions.

Enrico Bucci, a systems biologist and bioethicist at Temple University, published an open letter on his blog September 7 to draw The Lancet’s attention to suspected data manipulation. While he stresses that the letter is not an allegation, “the presentation of the data raises several concerns which require access to the original data to fully investigate.”

The study reports results of Russia’s Phase 1/2 clinical trial to assess the safety and effectiveness of its vaccine candidate, carried out by Moscow’s Gamaleya Institute. The tests took place between June and July ...

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Meet the Author

  • amanda heidt

    Amanda Heidt

    Amanda was an associate editor at The Scientist, where she oversaw the Scientist to Watch, Foundations, and Short Lit columns. When not editing, she produced original reporting for the magazine and website. Amanda has a master's in marine science from Moss Landing Marine Laboratories and a master's in science communication from UC Santa Cruz.
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