Singleron Introduces PythoN i™, Adding Nuclei Extraction and Tissue Homogenization Functions to its Tissue Processing System

Singleron Biotechnologies today announced the launch of PythoN i, an advanced tissue processing system that streamlines critical sample preparation steps for single cell sequencing, single nucleus sequencing, and DNA, RNA, and protein extraction.

| 1 min read

Share

PythoN i allows researchers to process up to eight samples concurrently with individualized temperature, rotation speed, duration, cycle number, and heating parameters. The system completes standard processing runs in just 15 minutes, significantly reducing sample preparation time.

“PythoN i integrates three essential tissue processing functions into a single platform," said Julia Peisert, Product Manager at Singleron Biotechnologies. "Researchers can now perform tissue dissociation, nuclei extraction, and tissue homogenization with one instrument, eliminating the need for multiple specialized devices."

The system's nuclei extraction capability delivers reproducible results for frozen tissues and challenging sample types where single nucleus sequencing provides better representation of cell populations, such as brain and muscle tissues. Additionally, PythoN i offers fast and efficient tissue homogenization to facilitate the extraction of DNA, RNA, and proteins.

PythoN i integrates seamlessly with Singleron's existing single cell and single nucleus sequencing workflows, providing researchers with a complete solution from sample preparation to analysis.

Press release provided by: Singleron Biotechnologies

Image of a woman in a microbiology lab whose hair is caught on fire from a Bunsen burner.
April 1, 2025, Issue 1

Bunsen Burners and Bad Hair Days

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

View this Issue
Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

sartorius logo
An illustration of PFAS bubbles in front of a blue sky with clouds.

PFAS: The Forever Chemicals

sartorius logo
Unlocking the Unattainable in Gene Construction

Unlocking the Unattainable in Gene Construction

dna-script-primarylogo-digital
Concept illustration of acoustic waves and ripples.

Comparing Analytical Solutions for High-Throughput Drug Discovery

sciex

Products

Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

Thermo Fisher Logo
Singleron Avatar

Singleron Biotechnologies and Hamilton Bonaduz AG Announce the Launch of Tensor to Advance Single Cell Sequencing Automation

Zymo Research Logo

Zymo Research Launches Research Grant to Empower Mapping the RNome

Magid Haddouchi, PhD, CCO

Cytosurge Appoints Magid Haddouchi as Chief Commercial Officer