Study Links Stress to a Faster-Aging Immune System

Health data from 5,744 adults over the age of 50 reveals an association between stressors such as discrimination and a relatively small proportion of younger infection-fighting immune cells.

Written byMargaret Osborne
| 4 min read
Artist’s rendering of aquamarine T cells in front of a blue and green background.
Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

A healthy immune response is key to fighting off diseases like COVID-19. As we age, however, our immune systems become less efficient at preventing illnesses, recovering from infection, and responding to vaccines. But not everyone’s immune system ages at the same rate—factors like smoking can accelerate this decline, while exercise can slow it down.

A study published last week in PNAS reports another contributor to immune aging: social stress.

“Stress exposure is literally wearing your body down,” says Ryon Cobb, a professor of psychology at the University of Georgia. “It goes along with this idea that the body never forgets.” Cobb wasn’t involved in the research, but study coauthor and University of Southern California (USC) gerontologist Eileen Crimmins was one of his postdoctoral instructors.

In the study, Crimmins and other USC researchers analyzed data from 5,744 adults over the age of 50 who had answered questions about stress and gave ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • Margaret Osborne

    Margaret Osborne is a freelance science journalist based in the Southwestern US. Her work has been published in Smithsonian magazine and Sag Harbor Express and has aired on WSHU Public Radio. She has a degree in journalism from Stony Brook University.

    View Full Profile
Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH