Study Links Stress to a Faster-Aging Immune System

Health data from 5,744 adults over the age of 50 reveals an association between stressors such as discrimination and a relatively small proportion of younger infection-fighting immune cells.

Written byMargaret Osborne
| 4 min read
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A healthy immune response is key to fighting off diseases like COVID-19. As we age, however, our immune systems become less efficient at preventing illnesses, recovering from infection, and responding to vaccines. But not everyone’s immune system ages at the same rate—factors like smoking can accelerate this decline, while exercise can slow it down.

A study published last week in PNAS reports another contributor to immune aging: social stress.

“Stress exposure is literally wearing your body down,” says Ryon Cobb, a professor of psychology at the University of Georgia. “It goes along with this idea that the body never forgets.” Cobb wasn’t involved in the research, but study coauthor and University of Southern California (USC) gerontologist Eileen Crimmins was one of his postdoctoral instructors.

In the study, Crimmins and other USC researchers analyzed data from 5,744 adults over the age of 50 who had answered questions about stress and gave ...

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Meet the Author

  • Margaret Osborne

    Margaret Osborne is a freelance science journalist based in the Southwestern US. Her work has been published in Smithsonian magazine and Sag Harbor Express and has aired on WSHU Public Radio. She has a degree in journalism from Stony Brook University.

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