Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.
Immunotherapy Treats Fibrosis in Mice
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
Immunotherapy Treats Fibrosis in Mice
Immunotherapy Treats Fibrosis in Mice

Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.

Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.

T cells
Artist’s rendering of aquamarine T cells in front of a blue and green background.
Study Links Stress to a Faster-Aging Immune System
Margaret Osborne | Jun 21, 2022
Health data from 5,744 adults over the age of 50 reveals an association between stressors such as discrimination and a relatively small proportion of younger infection-fighting immune cells.
A small, brown mouse runs on a narrow, miniature treadmill
How Exercise Helps Mice Fight Pancreatic Cancer
Dan Robitzski | Jun 15, 2022
A study reveals a molecular pathway linking exercise to an amped-up immune response to pancreatic cancer and greater responsiveness to treatment.
jigsaw puzzle with magnifying glass over the word "metastasis" 
Breast Cancer Cells Retrain T Cells to Invade Specific Tissues
Nele Haelterman, PhD
Scientists discover tumor-associated T cells that drive breast cancer metastasis to lymph nodes.
Illustration showing rod-shaped Mycobacterium tuberculosis bacteria in the lungs of a person with tuberculosis
Delayed T cell Response Allows Tuberculosis to Gain Foothold in Monkeys
Anna Napolitano | Jun 1, 2022
The results could help guide the design of new vaccines for the disease.
Tiliqua rugosa, sleepy lizard, on reddish soil in western Australia
Researchers Probe Genetics Behind a Lizard’s Odd Immune System
Hannah Thomasy | May 10, 2022
Deletions in the sleepy lizard genome leave it without an important type of T cells found in most other vertebrates.
COVID-19 vaccine vials
COVID-19 Vaccines Induce Better Long-Term Immunity than Infection
Jennifer Zieba, PhD
For the first time, researchers performed a head-to head longitudinal study comparing the immune response elicited by mRNA and traditional COVID-19 vaccines to primary infections.
A stained tissue sample of metastatic pancreatic cancer
Tetanus Immunity Protects Mice Against Pancreatic Cancer
Amanda Heidt | Mar 24, 2022
Because most people are vaccinated against tetanus as children, delivering benign bacteria carrying a tetanus antigen into pancreatic tumors makes them visible to memory cells in the immune system, researchers report.
illustration of inside of human chest with highlighted gland between the lungs
Genetically Altered Mice Harness Benefits of Calorie Restriction  
Sophie Fessl | Feb 11, 2022
A study identifies a gene that appears to be partially responsible for the health effects of a limited diet.
Motor neurons, undergoing degeneration in ALS
Mutant T Cells That Drive Amyotrophic Lateral Sclerosis (ALS) Progression May React To a Brain Antigen
Nele Haelterman, PhD
Scientists discovered a possibly autoreactive T cell population that forecasts and supports disease progression.
knitted pink heart with a mended hole
CAR T Cells Mend Broken Mouse Hearts
Sophie Fessl | Jan 6, 2022
Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.
Scanning electron micrograph showing cancer cell attached to T call via nanotube
Cancer Cell Nanotubes Hijack Mitochondria from Immune Sentinels
Sophie Fessl | Nov 30, 2021
The mitochondria stolen via these tiny connections give tumor cells a metabolic boost while the T cells are left weakened, according to in vitro experiments.
Peripheral blood mononuclear cells surrounded by red blood cells in circulating blood.
Accelerating Immune Research with Cryopreserved Peripheral Blood Mononuclear Cells
The Scientist Creative Services Team and MilliporeSigma
Commerically-available peripheral blood mononuclear cells offer a well-characterized, accessible, and consistent model for immunology and therapeutic development.
illustration of people of different genders and races
Does Biological Sex Influence COVID-19 Outcomes?
Annie Melchor | Nov 2, 2021
It’s unclear whether differing odds of dying between men and women reflect inherent differences between male and female immune systems or differences rooted in gender norms.
Stress Paralyzes Immune Cells
Emma Yasinski | Jul 1, 2021
Scientists show that an influx of noradrenaline can halt immune cells in mice.
Discover how counterflow centrifugation streamlines cell therapy workflows
Closed Cell Processing Systems for Cell Therapy Workflows
The Scientist Creative Services Team and Thermo Fisher Scientific
Closed systems increase cell therapy manufacturing process efficiency.
close-up of empty vaccine vials in a factory
The Quest for a Universal Coronavirus Vaccine
Diana Kwon | Jun 29, 2021
Scientists are on the hunt for a shot that will protect against not only SARS-CoV-2, but other members of its family that may emerge in the future.
Mucosal Vaccines Protect Mice from Viruses, Cancer
Emma Yasinski | Jun 1, 2021
Scientists use a protein found in mucus membranes to ferry vaccines to the lymph nodes.
Engineered Bacteria Make Tumors More T Cell-Friendly
Engineered Bacteria Make Tumors More T Cell-Friendly
Aparna Nathan
Microbes designed to produce specific immunomodulatory metabolites could give immunotherapy a boost.
Transmission electron microscope image of Zika virus particles
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
Ruth Williams | May 12, 2021
By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.