Because most people are vaccinated against tetanus as children, delivering benign bacteria carrying a tetanus antigen into pancreatic tumors makes them visible to memory cells in the immune system, researchers report.
The mitochondria stolen via these tiny connections give tumor cells a metabolic boost while the T cells are left weakened, according to in vitro experiments.
It’s unclear whether differing odds of dying between men and women reflect inherent differences between male and female immune systems or differences rooted in gender norms.
The Scientist Creative Services Team, Isoplexis | Oct 12, 2021
Explore how scientists characterize immune cell functional behavior in response to cancer, and how they harness this information for therapeutic purposes.
By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.
From his student days in veterinary medicine in Ethiopia to running a lab on metastasis at MD Anderson Cancer Center, Debeb has a passion for understanding how living things work.
The Scientist Creative Services Team in collaboration with MilliporeSigma | May 5, 2021
In this workshop, learn how to use hydrogel 3D cell culture plates for streamlined 3D cell culture colony formation, imaging, metabolic read-out, and T cell-mediated tumor cell killing.
A trio of papers shows that specialized antibodies can direct T cells to destroy cells that display portions of mutant cancer-related proteins, as well as T cells that have become cancerous themselves.
