By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.

In this workshop, learn how to use hydrogel 3D cell culture plates for streamlined 3D cell culture colony formation, imaging, metabolic read-out, and T cell-mediated tumor cell killing.

Katie McKenna discusses a combination CAR T and viral therapy that kills solid tumors.

From his student days in veterinary medicine in Ethiopia to running a lab on metastasis at MD Anderson Cancer Center, Debeb has a passion for understanding how living things work.

Mix-and-match shots could simplify vaccine rollout and stimulate more-robust immune responses. Ongoing clinical trials will soon give answers.

Researchers find key drivers of allograft rejection!

A trio of papers shows that specialized antibodies can direct T cells to destroy cells that display portions of mutant cancer-related proteins, as well as T cells that have become cancerous themselves.

Single-cell proteomics provides novel insights to COVID-19 disease progression

Alessandro Sette and Shane Crotty discuss the T cell response to SARS-CoV-2 and the implications for vaccine design and robust immune memory.

Outcomes in COVID-19 patients may be better in those recently infected with endemic coronaviruses. 

Researchers propose that an infusion of memory T cells from people who have recovered from SARS-CoV-2 infections could treat severe disease.

Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.

Some viruses, possibly even SARS-CoV-2, can sneak into the brain through the nose. Recent studies show that microglia are ready for them when they do.

Several routes exist for immune cells to communicate with neurons in the central nervous system, though T cells rarely come in direct contact with neural tissue.

The rare complication known as multisystem inflammatory syndrome in children (MIS-C) differs from both Kawasaki disease and severe adult cases of COVID-19, a study finds.

Gamma delta T cells in the meninges of the brain release a cell signaling molecule that does more than protect mice from microbial pathogens.

When tumor cells are infected with an oncolytic virus carrying a modified CD19 gene, they become targets for CAR T cells engineered to recognize this molecular marker.

Join us to learn about adoptive cell therapies from leading experts in the field of cancer immunology. 

Cancer therapies could potentially be more effective if their development took into account the cells that give rise to tumor-fighting cells.