Commensal Bacterium Reduces ALS Symptoms in Mice
Commensal Bacterium Reduces ALS Symptoms in Mice
Boosting the levels of Akkermansia muciniphila in mouse guts slowed the progression of an ALS-like disease, while two other microbiome members were associated with more severe symptoms.
Commensal Bacterium Reduces ALS Symptoms in Mice
Commensal Bacterium Reduces ALS Symptoms in Mice

Boosting the levels of Akkermansia muciniphila in mouse guts slowed the progression of an ALS-like disease, while two other microbiome members were associated with more severe symptoms.

Boosting the levels of Akkermansia muciniphila in mouse guts slowed the progression of an ALS-like disease, while two other microbiome members were associated with more severe symptoms.

amyotrophic lateral sclerosis (ALS)
Neuroscientist Rahul Desikan Dies
Neuroscientist Rahul Desikan Dies
Kerry Grens | Jul 19, 2019
He developed an MRI-based map of the human cortex, discovered genetic risk factors for neurodegenerative diseases, and wrote about his struggles with ALS.
Renowned Physicist Stephen Hawking Dies
Renowned Physicist Stephen Hawking Dies
Ashley Yeager | Mar 14, 2018
Famed for his work on black holes and cosmology, he also survived decades with amyotrophic lateral sclerosis.
CRISPR Proves Promising for Treating ALS in Mice
CRISPR Proves Promising for Treating ALS in Mice
Katarina Zimmer | Dec 21, 2017
The gene-editing tool was effective in disabling a defective gene responsible for some forms of amyotrophic lateral sclerosis. 
Image of the Day: When Cells Stop Cleaning
Image of the Day: When Cells Stop Cleaning
The Scientist Staff | Sep 12, 2017
By stifling autophagy in the motor neurons of a mouse model of amyotrophic lateral sclerosis (ALS), scientists stem later-stage disease progression.
Second-Ever ALS Drug Approved
Second-Ever ALS Drug Approved
Jef Akst | May 8, 2017
Amyotrophic lateral sclerosis patients in the U.S. now have an option besides riluzole, which was approved by the FDA more than two decades ago and only extends life by two or three months.
Additional #IceBucketChallenge Payoffs
Additional #IceBucketChallenge Payoffs
Jef Akst | Jul 28, 2016
Researchers identify a new ALS-associated gene thanks to funds generated by the social media challenge that went viral in summer 2014.
Book Review: <em>Personal Trials</em>
Book Review: Personal Trials
Arthur L. Caplan | Mar 22, 2016
At first blush, do-it-yourself clinical trials seem pointless and reckless. But a deeper truth pervades the research and the patients who drive it forward.
Endogenous Retrovirus Active in ALS
Endogenous Retrovirus Active in ALS
Jef Akst | Sep 30, 2015
Researchers uncover evidence that a retrovirus embedded within the human genome may play a role in the pathology of amyotrophic lateral sclerosis
#IceBucketChallenge Payoff
#IceBucketChallenge Payoff
Jef Akst | Aug 20, 2015
A year after the viral ALS awareness campaign raised millions, researchers say they have something to show for the influx of funds.