Two motor neurons are linked by a synapse.
| 3 min read
Researchers showed that large motor neurons face high metabolic stress, making them more prone to degeneration. Reducing this burden could lead to new ALS therapies.

amyotrophic lateral sclerosis (ALS)

Understanding Disease Through Biomarkers

Understanding Disease Through Biomarkers

Exploring the Gut Microbiome’s Role in Neurodegeneration

Exploring the Gut Microbiome’s Role in Neurodegeneration

An illustration of brains on a pink background.

Advancing Neuroscience Research with CyTOF Technology

Conceptual image of blue neuronal network showing synaptic activity in orange on a black background.

Characterizing Human Stem Cell-Derived Disease Models with Microelectrode Arrays

Journal club logo on purple background

The Scientist's Journal Club: Transcriptomics

Professor Alexandra Whiteley and graduate student Autumn Matthews look at an image of a western blot on their laboratory computer.

An Ancient Viral Protein May Play a Key Role in ALS

Abstract blue brain image

Integrating Technologies into Neurodegenerative Disease Research

TSS

Immune Cells and ALS: A Balance Between Life and Death

X-ray view of human brain with blood vessels

ApoA1 Identified as a Novel Target for ALS Therapy

Trending

A close-up image of a fly landing on a dessert

What Happens When a Fly Lands on Your Food? 

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

Image of an infant’s feet that are visible in a hospital incubator.

Record-Breaking DNA Sequencing Technology Could Transform Newborn Care

Red and green small tomatoes. A new genetic engineering approach helped gene-edited plants grow faster.

Gene-Edited Crops Grow Faster with a Little Help from Bacteria

Multimedia

Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

fujirebio logo

Products

Labvantage Logo

LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

The Scientist Placeholder Image

Evosep Unveils Open Innovation Initiative to Expand Standardization in Proteomics

OGT logo

OGT expands MRD detection capabilities with new SureSeq Myeloid MRD Plus NGS Panel