Humans Can Survive Without Key Autophagy Gene
Humans Can Survive Without Key Autophagy Gene
Loss of the protein ATG7 is fatal in mice, but not always for people—although it is linked to human neurodevelopmental disorders, researchers report.
Humans Can Survive Without Key Autophagy Gene
Humans Can Survive Without Key Autophagy Gene

Loss of the protein ATG7 is fatal in mice, but not always for people—although it is linked to human neurodevelopmental disorders, researchers report.

Loss of the protein ATG7 is fatal in mice, but not always for people—although it is linked to human neurodevelopmental disorders, researchers report.

autophagy
Computational Biologist Bing Liu Dies in Suspected Murder
Computational Biologist Bing Liu Dies in Suspected Murder
Kerry Grens | May 7, 2020
The University of Pittsburgh scientist, who was studying SARS-CoV-2, was shot to death in his home.
Image of the Day: Cellular Breakdown
Image of the Day: Cellular Breakdown
Carolyn Wilke | Jan 31, 2019
Autophagy may keep cell division in check to help protect against cancer-causing DNA damage.
<em>The Scientist</em>&rsquo;s Most Stunning Infographics of 2018
The Scientist’s Most Stunning Infographics of 2018
Jef Akst | Dec 21, 2018
From cellular self-digestion to the effects of exercise on the brain, our features editor picks her favorite art custom-made for the magazine.
Image of the Day: Pseudomonas Autophagy
Image of the Day: Pseudomonas Autophagy
The Scientist Staff, The Scientist Staff | Mar 30, 2018
Researchers identify antibacterial functions of cell death in Arabidopsis when the plant is infected with Pseudomonas.  
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Image of the Day: When Cells Stop Cleaning
Image of the Day: When Cells Stop Cleaning
The Scientist Staff | Sep 12, 2017
By stifling autophagy in the motor neurons of a mouse model of amyotrophic lateral sclerosis (ALS), scientists stem later-stage disease progression.
Vlad Denic on Exploring New Fields and Failing Successfully
Vlad Denic on Exploring New Fields and Failing Successfully
Ben Andrew Henry | Dec 1, 2016
The Harvard professor is pursuing fundamental questions about autophagy, protein homeostasis, and other cellular processes, and he’s always on the lookout for his next new topic.
Autophagy Pioneer Wins Nobel
Autophagy Pioneer Wins Nobel
Kerry Grens | Oct 2, 2016
Biologist Yoshinori Ohsumi is honored for his discoveries on the mechanisms of cellular recycling.
Cocaine Induces Neuronal Autophagy
Cocaine Induces Neuronal Autophagy
Jef Akst | Jan 19, 2016
A new study supports the idea that cocaine triggers brain cells to eat themselves and suggests a possible antidote.
Targeted ER Breakdown
Targeted ER Breakdown
Ashley P. Taylor | Jun 16, 2015
Researchers identify receptors that target the endoplasmic reticulum for degradation by autophagy in yeast and mice. 
Toggling Between Life and Death
Toggling Between Life and Death
Ashley P. Taylor | Apr 1, 2015
In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.
Synaptic Pruning Improves Autism in Mice
Synaptic Pruning Improves Autism in Mice
Kerry Grens | Aug 25, 2014
Fixing impaired pruning and autophagy signaling in neurons eases the symptoms of autism in a mouse model of the disorder.
Autophagy Revives Dying Cancer Cells
Autophagy Revives Dying Cancer Cells
Kerry Grens | Apr 7, 2014
Self digestion thwarts self destruction.  
Waste-Management Consultant
Waste-Management Consultant
Megan Scudellari | Nov 1, 2013
By audaciously pursuing an abandoned area of research, Ana María Cuervo discovered how cells selectively break down their waste, and revealed the health consequences when that process malfunctions.
Autophagy’s Role in Alzheimer’s
Autophagy’s Role in Alzheimer’s
Abby Olena | Oct 3, 2013
Researchers show that amyloid beta is secreted from neurons in an autophagy-dependent manner.
Citations Predict Nobel Winners?
Citations Predict Nobel Winners?
Bob Grant | Sep 24, 2013
Thomson Reuters makes its annual data-based picks for which scientists could collect medals in Stockholm later this year.
Fixing Fly Forgetfulness
Fixing Fly Forgetfulness
Kate Yandell | Sep 3, 2013
Polyamines help fruit flies retain memories as they age.
Munching Macrophages
Sabrina Richards | Jul 1, 2012
Making macrophages in atherosclerotic plaques digest spent organelles instead of dying may help keep plaques stable.
News from AAAS
Jef Akst | Feb 20, 2012
A roundup of recent research announced last weekend at the annual conference of the American Association for the Advancement of Science (AAAS).