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Image of the Day
Image of the Day: Pseudomonas Autophagy
Staff, The Scientist Staff | Mar 30, 2018
Researchers identify antibacterial functions of cell death in
when the plant is infected with
Eat Yourself to Live: Autophagy’s Role in Health and Disease
Vikramjit Lahiri and Daniel J. Klionsky | Mar 1, 2018
New details of the molecular process by which our cells consume themselves point to therapeutic potential.
Image of the Day: When Cells Stop Cleaning
Staff | Sep 12, 2017
By stifling autophagy in the motor neurons of a mouse model of amyotrophic lateral sclerosis (ALS), scientists stem later-stage disease progression.
Vlad Denic on Exploring New Fields and Failing Successfully
Ben Andrew Henry | Dec 1, 2016
The Harvard professor is pursuing fundamental questions about autophagy, protein homeostasis, and other cellular processes, and he’s always on the lookout for his next new topic.
Autophagy Pioneer Wins Nobel
Kerry Grens | Oct 3, 2016
Biologist Yoshinori Ohsumi is honored for his discoveries on the mechanisms of cellular recycling.
Cocaine Induces Neuronal Autophagy
Jef Akst | Jan 19, 2016
A new study supports the idea that cocaine triggers brain cells to eat themselves and suggests a possible antidote.
Targeted ER Breakdown
Ashley P. Taylor | Jun 17, 2015
Researchers identify receptors that target the endoplasmic reticulum for degradation by autophagy in yeast and mice.
Toggling Between Life and Death
Ashley P. Taylor | Apr 1, 2015
In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.
Synaptic Pruning Improves Autism in Mice
Kerry Grens | Aug 25, 2014
Fixing impaired pruning and autophagy signaling in neurons eases the symptoms of autism in a mouse model of the disorder.
Autophagy Revives Dying Cancer Cells
Kerry Grens | Apr 7, 2014
Self digestion thwarts self destruction.