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| 1 min read

Understanding the Role of Autophagy in Infectious Disease

Josephine Thinwa shares her journey to becoming a physician scientist and how this led her to investigate the role of a neurologically important kinase in virus-induced autophagy.

The image shows a rendering of a human brain viewed from a lateral perspective with the cerebellum, highlighted in yellow and orange, is situated at the bottom part of the brain where the cerebrum connects with the brainstem.

| 3 min read

Revealing the Mutation Behind a Rare Neurological Disease

Two cells fluorescently stained for normal (red) and damaged (green) lysosomes.

| 4 min read

Cancer Cells Spread When They Stop Recycling Waste

autophagy

Orange rod-shaped bacteria over a red and purple background.

Macrophages Curtail Tuberculosis

Danielle Gerhard, PhD | | 2 min read

Programmed Cell Death: Mechanisms for Cellular Self-Destruction

Programmed Cell Death Pathways

Elina Kadriu | | 7 min read

Photo of Chantell Evans

Chantell Evans Tracks Mitochondrial Cleanup in Neurons

Holly Barker, PhD | | 3 min read

A colored microscopy image showing cells that are dying in yellow and healthy cells in blue

Sweet Taste Receptors Regulate Proteins in Developing Fruit Flies

Tess Joosse | | 2 min read

A colored microscope image of a cross section of a human artery filled with fatty plaques

Protein-Recycling Process Protective Against Arterial Plaques

Clare Watson | | 2 min read

Autophagy and Mitophagy in Neurodegeneration: A Deep Dive

Autophagy and Mitophagy in Neurodegeneration: A Deep Dive

Available on Demand

A drawing of pseudostratified gut epithelial cells in the early intestines, cells in red and nucleus in purple.

Move Over Apoptosis: Another Form of Cell Death May Occur in the Gut

Natalia Mesa, PhD | | 6 min read

Discover how to scale up cellular assays during drug discovery

High-Throughput Solutions for Lead Candidate Discovery

Thermo Fisher ScientificandThe Scientist | | 1 min read

An illustration of a yeast cell (right) and a human neuron (left) showing the processes/features that are similar in the two

Infographic: Modeling Neurodegenerative Diseases with Yeast

Mahlon Collins | | 10+ min read

Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.

Yeast Models Provide New Insights into Neurodegenerative Diseases

Mahlon Collins | | 10+ min read

cartoon image of a brain against a black background

Humans Can Survive Without Key Autophagy Gene

Annie Melchor | | 4 min read

bing liu university of pittsburgh school of medicine

Computational Biologist Bing Liu Dies in Suspected Murder

Kerry Grens | | 1 min read

Image of the Day: Cellular Breakdown

Carolyn Wilke | | 1 min read

The Scientist’s Most Stunning Infographics of 2018

Jef Akst | | 2 min read

Image of the Day: Pseudomonas Autophagy

The ScientistandThe Scientist Staff | | 1 min read

Eat Yourself to Live: Autophagy’s Role in Health and Disease

Vikramjit LahiriandDaniel J. Klionsky | | 10+ min read

Image of the Day: When Cells Stop Cleaning

The Scientist | | 1 min read

Vlad Denic on Exploring New Fields and Failing Successfully

Ben Andrew Henry | | 3 min read

Autophagy Pioneer Wins Nobel

Kerry Grens | | 3 min read

Cocaine Induces Neuronal Autophagy

Jef Akst | | 1 min read

Page 1 of 2 - 40 Total Items

Trending

A red male cardinal and a brownish female sit on a branch in front of a green background.

Sex Determination: It’s in the Genes—Sometimes

Animals across the tree of life have developed a mind-boggling variety of ways to become male or female.

A group of large animals, some of which are being studied for cancer resistance genes and proteins, are pictured, including a bison, an elephant, a giraffe, a manatee, a zebra, and a whale.

Peto’s Paradox: How Gigantic Species Evolved to Beat Cancer

Scientists dive into the genomes of whales, elephants, and other animal giants looking for new weapons in the fight against cancer.

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

A cross-section of a mouse brain with staining for NOVA1 and cell nuclei.

Strange Squeaks: A Uniquely Human Gene Alters Mouse “Songs”

A human-specific NOVA1 variant changed mouse vocalizations, potentially providing insights into the evolution of language.

Multimedia

Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

Learn how mastering the ins and outs of PCR can accelerate workflows and improve data.

Understanding Disease Through Biomarkers

Understanding Disease Through Biomarkers

Learn how scientists identify and characterize biomarkers for cancer, neurodegenerative diseases, and autoimmune disorders.

A greyscale image of cells dividing.

March 2025, Issue 1

How Do Embryos Know How Fast to Develop

In mammals, intracellular clocks begin to tick within days of fertilization.

View this Issue

Research Resources

Podcasts

Webinars

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eBooks

Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

Learn how mastering the ins and outs of PCR can accelerate workflows and improve data.

Explore polypharmacology’s beneficial role in target-based drug discovery

Embracing Polypharmacology for Multipurpose Drug Targeting

Polypharmacology allows scientists to explore novel therapeutic purposes for existing drugs and opens new doors to treat multifactorial diseases.

3D rendered cross section of influenza viruses, showing surface proteins on the outside and single stranded RNA inside the virus

Genetic Insights Break Infectious Pathogen Barriers

Molecular detection technologies help scientists rapidly and reliably find and address ever-evolving pathogens with optimal accuracy and sensitivity.

A photo of sample storage boxes in an ultra-low temperature freezer.

Navigating Cold Storage Solutions

Discover the key features to consider when selecting a new refrigerator or freezer

Products

Product News

Zymo Research Launches the Quick-16S™ Full-Length Library Prep Kit

Zymo Research Corp., a leader in biotechnology and microbiome research solutions, proudly announces the launch of its new Quick-16S™ Full-Length Library Prep Kit.

BIOVECTRA is Honored with 2025 CDMO Leadership Award for Biologics

Industry Recognizes BIOVECTRA’s Excellence in Microbial Fermentation, Recombinant Protein Production, and Aseptic Fill-Finish Capabilities

Gilead’s Capsid Revolution Meets Our Capsid Solutions: Sino Biological – Engineering the Tools to Outsmart HIV

On February 18, 2025, Gilead Sciences announced a significant milestone: the U.S. FDA accepted their New Drug Applications (NDAs) for lenacapavir (LEN), a groundbreaking twice-yearly injectable HIV-1 capsid inhibitor for pre-exposure prophylaxis (PrEP).

Stirling Ultracold

Meet the Upright ULT Built for Faster Recovery - Stirling VAULT100™

Slow temperature recovery can threaten the integrity of your work. That’s Stirling Ultracold designed the VAULT100™ to operate at setpoints down to -100°C, so your samples may never be exposed to temperatures above -70°C during a typical door opening.

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