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Synaptic Pruning Improves Autism in Mice
Kerry Grens | Aug 25, 2014
Fixing impaired pruning and autophagy signaling in neurons eases the symptoms of autism in a mouse model of the disorder.
Autophagy Revives Dying Cancer Cells
Kerry Grens | Apr 7, 2014
Self digestion thwarts self destruction.
Megan Scudellari | Nov 1, 2013
By audaciously pursuing an abandoned area of research, Ana María Cuervo discovered how cells selectively break down their waste, and revealed the health consequences when that process malfunctions.
Autophagy’s Role in Alzheimer’s
Abby Olena | Oct 3, 2013
Researchers show that amyloid beta is secreted from neurons in an autophagy-dependent manner.
Citations Predict Nobel Winners?
Bob Grant | Sep 25, 2013
Thomson Reuters makes its annual data-based picks for which scientists could collect medals in Stockholm later this year.
Fixing Fly Forgetfulness
Kate Yandell | Sep 3, 2013
Polyamines help fruit flies retain memories as they age.
Sabrina Richards | Jul 1, 2012
Making macrophages in atherosclerotic plaques digest spent organelles instead of dying may help keep plaques stable.
News from AAAS
Jef Akst | Feb 20, 2012
A roundup of recent research announced last weekend at the annual conference of the American Association for the Advancement of Science (AAAS).
How Autophagy Works
Muriel Mari, Sharon A. Tooze, and Fulvio Reggiori | Feb 1, 2012
There are five steps of autophagosome biogenesis: induction, expansion, vesicle completion, fusion, and cargo degradation.
On the Menu
Mary Beth Aberlin | Feb 1, 2012
Digestion on the cellular level: two mysteries examined