Hands wearing blue gloves use scissors and forceps to cut DNA.

| 9 min read

David Liu Wins 2025 Breakthrough Prize for Base Editing and Prime Editing

New precision genome editing technologies are transforming the therapeutic landscape for patients with certain cancers and genetic diseases.

A cross-section showing blue, white, and green-colored cells against a black background.

| 4 min read

Correcting the Mutation Behind a Genetic Eye Disease

Two hands holding tweezers and dissecting single points in a DNA sequence.

| 5 min read

From CRISPR to Prime Editing: The Evolution of the Genome Editing Revolution

base editing

A hand pulling out bases from DNA using forceps.

MOBE: A Base Editor That Multitasks without Mix-ups

Aparna Nathan, PhD | | 3 min read

3D cubes showing letters representing the four DNA bases (adenine, guanine, cytosine, and thymine) and small DNA helices.

Discovering the Functions of Noncoding Sequence Variants

Niki Spahich, PhD | | 4 min read

Molecular illustration of CRISPR editing the DNA double helix

Prime Time Precision with CRISPR Technologies

The Scientist | | 1 min read

Genotoxic Effects of Base and Prime Editing

Kamal Nahas, PhD | | 5 min read

3D structural model of a Cas protein and sgRNA targeting and unwinding DNA for gene editing.

CRISPR Gene Editing: Cas9 and Beyond

Deanna MacNeil, PhDandJohanna Pruller, PhD | | 7 min read

Artist’s impression of stem cells. The cells have a transparent cell membrane on a pale blue background.

Overcoming Cancer Therapy Obstacles With Epitope Editing

Rebecca Roberts, PhD | | 3 min read

David Liu

Targeting a Genetic Accident to Treat Disease

Deanna MacNeil, PhD | | 2 min read

Medical illustration of a scientist replacing part of a DNA molecule with tweezers, representing genome editing.

On the Hunt for the Next Breakthrough in Motor Neuron Disease

Deanna MacNeil, PhD | | 3 min read

Cas9 enzyme

Molecular Glue ‘Shreds’ Cas9 and Enables a New Form of CRISPR Control

Ida Emilie Steinmark, PhD | | 3 min read

Illustration of DNA

Can “Gene Writing” Deliver What Gene Editing Can’t?

Dan Robitzski | | 10+ min read

3D representation of a DNA helix and with a base offset from the main helix, illustrating the concept of base editing.

A CRISPR Alternative for Correcting Mutations That Sensitize Cells to DNA Damage

Deanna MacNeil, PhD | | 3 min read

A gloved hand holds a tweezer and pulls a section of DNA away from a double helix

First Person Dosed in Novel Gene Editing Clinical Trial

Amanda Heidt | | 4 min read

Technique Talk: Understanding Cancer One Base Edit at a Time

Technique Talk: Understanding Cancer One Base Edit at a Time

Available on Demand

DNA

In Editing RNA, Researchers See Endless Possibilities

Christie Wilcox, PhD | | 10+ min read

CRISPR, TALENs, ZFNs, gene editing, base editing, mitochondria, DNA, mtDNA

New Gene Editing Tool Corrects Mutations in Mitochondrial DNA

Amanda Heidt | | 3 min read

prime editing crispr cas9 genome editing techniques

New “Prime Editing” Method Makes Only Single-Stranded DNA Cuts

Emma Yasinski | | 4 min read

a target surrounded by arrows that missed

Base Editors Cause Off-Target Mutations in RNA

Catherine Offord | | 2 min read

Better Base Editing in Plants

Ruth Williams | | 3 min read

MO infographic

Infographic: Plant Genome Editors Get A New Tool

Ruth Williams | | 1 min read

CRISPR Editing Heads Off Disease in Mouse Livers

Shawna Williams | | 2 min read

Page 1 of 2 - 27 Total Items

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Universe 25 Experiment

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What are the Risks and Benefits of a Cold Plunge?

Cold-water immersion enthusiasts tout its benefits for their health and wellbeing, but is it backed by scientific evidence?

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Mitochondrial DNA: A Maternal Legacy That Helps Trace the Past and Diagnose the Future

The mitochondrial genome can help researchers map ancestry and better understand the inheritance of mitochondrial diseases.

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Transform Omics Workflows with Scalable Cell Prep

Levitation-based cell enrichment streamlines workflows and enhances reproducibility.

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Accelerating Cancer Research Through Comprehensive Genomic Analysis

Learn how the latest technology helps researchers overcome cancer research challenges.

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May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

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TaqMan Probe & Assays: Unveil What's Possible Together

Fuel your research with our high-quality TaqMan™ Assays and probes. Experience unmatched performance, reliability, and detailed support tailored to your scientific needs. Click to explore our comprehensive coverage options now!

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

In this webinar, Andre Mueller will introduce Aunty, the latest tool that scientists use for rapid, high-resolution protein stability testing.

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

In this webinar, Nathan Sepulveda will share how to specifically and reproducibly measure residual HEK293 DNA during biotherapeutic product development.

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Making Real-Time PCR More Straightforward

Today’s thermocyclers are more intuitive and flexible, letting scientists focus on their experiments rather than their instruments.

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Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Long-lasting, bright F-actin staining made easy with Biotium's new ActinBrite™ High Affinity Phalloidin Conjugates.

Latest AI software simplifies image analysis and speeds up insights for scientists

The Aivia 15 release includes deep learning-powered tools for 2D and 3D cell segmentation.

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

The integrated solution enables parallel high-resolution analysis of hundreds to thousands of individual cells, addressing growing demand for scalable, multiomics approaches in single-cell research.

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Agilent BioTek Cytation C10 Confocal Imaging Reader

From confocal, widefield, and live cell imaging to multimode reading, the Agilent BioTek Cytation C10 confocal imaging reader delivers crisp, high-resolution images and the ability to image and analyze 3D samples.