With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.

Researchers use base-editing to swap out an erroneous nucleotide responsible for a potentially life-threatening blood disorder.

Combining a modified Cas9 enzyme with an unrelated one derived from the immune system of the sea lamprey, researchers demonstrate yet another way to edit a single DNA nucleotide. 

Researchers develop a CRISPR-based technique that efficiently corrects point mutations without cleaving DNA.