A study links the loss of DNA methylation across the genome—as is common in cancer—to the disruption of the 3-D compartments that organize the genome and to the timing of DNA replication.

New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.

Telomeres in cancer cells exposed to oxidative stress got shorter and stickier.

Scientists use stem-like cells from patients’ aggressive, triple receptor-negative breast tumors to grow cell lines for research.

She will also be an executive producer on the HBO Films project, which is based on a 2010 book about the life of Henrietta Lacks.

From tossing out cross-contaminated cell lines to flagging genomic misnomers, a push is on to tidy up biomedical research.

More than 50 years after cross-contamination of cultured cell lines was recognized, the problem continues to plague the scientific community.

Antibody barcoding allows scientists and clinicians to analyze protein expression in small amounts of cancer tissue.

Researchers develop several thousand haploid human cell lines, each with a different gene mutant.

NCI has made public the largest-ever database of cancer-specific gene variations, paving the way for the development of new drugs and therapies.

Researchers show that peptides isolated from certain types of soybean inhibit the growth of human colon, liver, and lung cancer cells.
 

Enhancing data collection from emulsion PCR reactions: three case studies

Two new cancer cell line databases bursting with genomic and drug profiling data may help researchers identify drug targets.