Illustration of a jackalope
On the Trail of the Jackalope
How horned rabbits led the way to the HPV vaccine
ABOVE: ©shutterstock.com, BlueLotusArt
On the Trail of the Jackalope
On the Trail of the Jackalope

How horned rabbits led the way to the HPV vaccine

How horned rabbits led the way to the HPV vaccine

ABOVE: ©shutterstock.com, BlueLotusArt

cancer vaccines

Salmonella (pink) invading a human epithelial cell (yellow)
Modified Salmonella Revs Immune Response, Combats Tumors in Mice
Natalia Mesa | Feb 3, 2022
When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.
personalized vaccines
Infographic: Neoantigen Prediction for Personalized Vaccine Design
Jasreet Hundal, Elaine R. Mardis | Jul 15, 2019
See how a computational pipeline uses next-generation sequencing data to identify genetic alterations that produce cancer-specific antigens.
custom targeted cancer vaccine
Personalized Cancer Vaccines in Clinical Trials
Jasreet Hundal, Elaine R. Mardis | Jul 15, 2019
The field is young, but predicting antigens produced by patients’ malignant cells could yield successful treatments for individuals with a range of cancer types.
Table: Personalized Cancer Vaccine Trials in the United States
Jasreet Hundal, Elaine R. Mardis | Jul 15, 2019
There are currently more than two dozen ongoing Phase 1 and Phase 2 trials using different vaccine platforms such as DNA, RNA, synthetic long peptides, and dendritic cells.
Locally-Injected Immunotherapy Eradicates Tumors in Mice
Diana Kwon | Feb 1, 2018
The treatment also curbed the growth of nearby metastases that did not receive the drug.
Personalized Cancer Vaccines Show Promise for Melanoma
Jef Akst | Jul 6, 2017
In two early trials, vaccines tailored to the mutations in individuals’ cancers appeared to protect 12 of 19 patients against relapse. 
Gel Scaffolds for Delivery of Immunotherapies
Rachel Berkowitz | Apr 1, 2017
Using biocompatible polymers to carry cancer immune therapies directly to the tumor