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DNA cell on scientific background
Mechanism of a Genome Packaging Machine Discovered
Detailed analyses of cohesin’s movements indicate how this protein complex hauls chromatin fibers to package DNA into loops.
Mechanism of a Genome Packaging Machine Discovered
Mechanism of a Genome Packaging Machine Discovered

Detailed analyses of cohesin’s movements indicate how this protein complex hauls chromatin fibers to package DNA into loops.

Detailed analyses of cohesin’s movements indicate how this protein complex hauls chromatin fibers to package DNA into loops.

chromatin structure
The hinge region of cohesin pulls DNA to two head regions, like a person’s hand-to-hand motion of pulling on a rope.
Infographic: How Genome-Packaging Protein Cohesin Handles DNA
Ruth Williams | Jan 17, 2022 | 1 min read
The hinge region of cohesin pulls DNA to two head regions, like a person’s hand-to-hand motion of pulling on a rope.
An electron microscopy image of a cell with the nucleolus shown in blue, chromatin in green, and nuclear envelope in red
Aging in Mice Linked to Misexpression of Class of Genes
Sophie Fessl, PhD | Dec 21, 2021 | 4 min read
Genes lacking a particular structure known as CpG islands tend to go haywire in older cells, a study finds, potentially contributing to key facets of aging. But it’s not yet clear if the relationship is causal.
Obituary, University of Oregon, Biochemistry, Molecular Biology, chromatin, chromatin reordering, chromatin reprogramming,
Molecular Biologist Jeff McKnight Dies at 36
Amanda Heidt | Oct 8, 2020 | 3 min read
The University of Oregon scientist studied the structure and function of chromatin, with the intent of designing new therapeutic tools.
Image of the Day: Chromatin Forest
Emily Makowski | Jan 14, 2020 | 1 min read
The DNA-protein complex has branches that fold back on themselves.
Imaging Chromatin to Deduce Function from Form
Marissa Fessenden | Dec 1, 2018 | 7 min read
Researchers describe their tools for probing how the physical shape of the genome affects genes’ function.
New Techniques Detail Embryos’ First Hours and Days
Jef Akst | Dec 1, 2017 | 10+ min read
New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.
Infographic: How Embryos Take Control of Their Own Development
Jef Akst | Nov 30, 2017 | 3 min read
The switch from maternal factors involves dynamic reprogramming of the zygotic genome.
Study: DNA Folding Patterns Revealed
Aggie Mika | Jul 28, 2017 | 2 min read
Recent data suggest that instead of folding into rigid higher-order structures, chromatin is malleable and diverse.
Methylation Maestro
Anna Azvolinsky | Jan 1, 2017 | 9 min read
After initially discovering that DNA methylation represses transcription, Howard Cedar continues to explore how the epigenetic mark regulates gene expression.
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