a photo of the packaging for the drug Trikafta
FDA Approves New Cystic Fibrosis Drug
The treatment, Trikafta, increases lung function in most patients with the disease—but comes with a hefty price tag.
FDA Approves New Cystic Fibrosis Drug
FDA Approves New Cystic Fibrosis Drug

The treatment, Trikafta, increases lung function in most patients with the disease—but comes with a hefty price tag.

The treatment, Trikafta, increases lung function in most patients with the disease—but comes with a hefty price tag.

cystic fibrosis
Don Ingber engineered cystic fibrosis airway chips that recapitulate patient symptoms.
A New Model of Lung Disease Paves the Way for Personalized Treatments
Nele Haelterman, PhD | May 9, 2022
Scientists engineered a lung-on-a-chip model from patient cells that mimics cystic fibrosis.
Genetically Modified Viral Cocktail Treats Deadly Bacteria in Teen
Ashley Yeager | May 8, 2019
Tweaking the genomes of two phages and combining them with a third phage helped to clear a persistent Mycobacterium infection in the patient.
Lack of Diversity in Genetic Datasets is Risky for Treating Disease
Ashley Yeager | Mar 21, 2019
Certain populations have been historically underrepresented in genome sequencing studies, but the NIH, private clinics, and 23andMe and other companies are trying to fix that.
Image of the Day: Breathe In
Carolyn Wilke | Jan 14, 2019
Inhalable particles carrying mRNA make mouse lungs glow.
New Lung Cell Identified
Abby Olena | Aug 1, 2018
The cell type was discovered via single-cell RNA sequencing of thousands of cells in mouse and human airways and may play a role in cystic fibrosis.
CF Gene Therapy Shows Promise
Jef Akst | Jul 6, 2015
The results of a Phase 2 trial suggest that delivering normal copies of the gene that causes cystic fibrosis may slow lung decline.
Genome Digest
Jenny Rood | Apr 16, 2015
What researchers are learning as they sequence, map, and decode species’ genomes
Breathing Life into Lung Microbiome Research
Rina Shaikh-Lesko | Jun 9, 2014
Although it’s far less populated than the mouth community that helps feed it, researchers increasingly appreciate the role of the lung microbiome in respiratory health.
FDA Approves NGS Tests
Tracy Vence | Nov 21, 2013
The agency has cleared marketing of four next-generation sequencing devices from Illumina.
The Road Less Traveled
Megan Scudellari | Nov 1, 2012
First, Aravinda Chakravarti drew a map of how scientists might unravel the genetics of complex disease. Then he blazed the trail.
Cystic Fibrosis Alters Microbiome?
Edyta Zielinska | Sep 28, 2012
The microbiome of the lung is different in patients with the disease, which causes a thick buildup of mucus that makes breathing difficult.
Novel Cystic Fibrosis Drug Approved
Megan Scudellari | Feb 1, 2012
After a lightning-fast approval, the first medicine to treat an underlying cause of the disorder hits the market.
Infection Selection
Ruth Williams | Nov 13, 2011
Scientists track changes in bacterial genomes during a hospital outbreak to discover potential pathogenesis genes.