So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.

In an unexpected twist in neuroscience dogma, the cells on the receiving end of neurotransmission appear to be able to release glutamate to regulate the transmitting cell’s activity.

Overactive immune cells identified in a mouse model and in postmortem human brain tissue may offer a potential therapeutic target for cognitive delays associated with the condition, researchers report.

Researchers have recorded tens of thousands of brain cells in mice as the animals transitioned from feeling thirsty to quenched.

Recordings of electrical activity in porcine brains finds similarities to rodent neural tissue.

After a decades-long pursuit, researchers have confirmed the identity of the pore of the mechanotransduction channel in vertebrates’ inner ear hair cells.

Software that can separate signals from noise brings neuroscientists a step closer to understanding neurons’ patterns of communication.

Micrometer-size magnetrodes detect activity-generated magnetic fields within living brains.

Newly designed sensors detect the magnetic fields generated by electrical activity within cat brains.

Deep within the forebrains of mice, scientists have identified an elusive cell type responsible for forming habits.

Two groups of scientists combined automation with two-photon microscopy to target and record specific neurons in living animals. 

Imaging and manipulating the brain has come a long way from electrodes and the patch clamp, though such traditional tools remain essential.

Flexible patches of silicone that stick to skin and conduct electricity could serve as the basis for a new, reusable electrode for medical applications.

The Scientist’s choice of major improvements in imaging, optogenetics, single-cell analyses, and CRISPR

Researchers use a conducting polymer to construct circuits inside plant cuttings in a proof-of-concept study.

Cortical interneurons in mice exhibit activity-dependent alterations to their characteristic firing patterns.

Optical techniques for monitoring action potentials

Emil du Bois-Reymond’s innovations for recording electrical signals from living tissue set the stage for today’s neural monitoring techniques.

Scientists adapt an in vivo retina recorder for ex vivo use.