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Two neurons communicating with electrical signals
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Semi-automated technologies allow researchers to scale up their high density microelectrode array experiments in iPSC-derived neuronal cultures.
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electrophysiology

Photo of a cat with its shadow blending with the shadows of slats.

A Serendipitous Shadow Brought the Brain’s Visual Pathways to Light

Artist’s rendering of a neuron within a network.

Visualizing Neuronal Activity with High-Speed Voltage Imaging

Image of an axon, with a callout box highlighting a portion of the cell membrane. It depicts three different electrodes and ion channels along the membrane.

What’s the Difference Between a Voltage Clamp and a Current Clamp?

Illustration showing high-resolution ion channel recordings using the patch clamp technique

Patch Clamp: Unlocking the Secrets of Ion Channels in Electrophysiology

Conceptual image of blue neuronal network showing synaptic activity in orange on a black background.

Characterizing Human Stem Cell-Derived Disease Models with Microelectrode Arrays

a Taenia solium parasite, a human brain, and lines that represent an electroencephalogram (EEG) recording.

How a Parasite Excites the Brain

A male tsetse fly smells a tsetse fly pheromone

Elusive Tsetse Pheromones

Microscope image of interconnected neurons, which appear as colorful starbursts of light.

How Neurons in a Dish Learned to Play “Pong”

panel depicting mossy fiber synapses and glutamate signaling dynamics

Infographic: Reverse Signaling Between Neurons

Trending

A team of cartoon scientists studying a giant pancreas.

Prolonged GLP-1 Exposure Remodels Gene Expression in the Pancreas by Flipping a Molecular Switch

Image of a Diploptera punctata cockroach.

Cockroach Milk Proteins Churn Out an Ig Nobel Win

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

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Editors Mass Resign from Elsevier Journal After Editor-in-Chief Let Go

Multimedia

Essential Genes Are Dominantly Activated by Single Transcription Factors

Essential Genes Are Dominantly Activated by Single Transcription Factors

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Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

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The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

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Essential Genes Are Dominantly Activated by Single Transcription Factors

Essential Genes Are Dominantly Activated by Single Transcription Factors

EpiCypher Logo
Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Miltenyi
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad

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Single cells in suspension

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