Infographic: Reverse Signaling Between Neurons
Infographic: Reverse Signaling Between Neurons
So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.
Infographic: Reverse Signaling Between Neurons
Infographic: Reverse Signaling Between Neurons

So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.

So-called mossy fiber synapses in the hippocampus can meter the amount of neurotransmitter they receive by sending glutamate against the usual direction of synaptic flow.

electrophysiology
Hippocampal Cell Communication Is Bidirectional: Study
Hippocampal Cell Communication Is Bidirectional: Study
Christie Wilcox | Jun 4, 2021
In an unexpected twist in neuroscience dogma, the cells on the receiving end of neurotransmission appear to be able to release glutamate to regulate the transmitting cell’s activity.
Study Points to Novel Role for Microglia in Down Syndrome
Study Points to Novel Role for Microglia in Down Syndrome
Catherine Offord | Oct 6, 2020
Overactive immune cells identified in a mouse model and in postmortem human brain tissue may offer a potential therapeutic target for cognitive delays associated with the condition, researchers report.
Thirst and Drinking Spark Widespread Activity in the Mouse Brain
Thirst and Drinking Spark Widespread Activity in the Mouse Brain
Ruth Williams | Apr 4, 2019
Researchers have recorded tens of thousands of brain cells in mice as the animals transitioned from feeling thirsty to quenched.
Image of the Day: This Little Piggy
Image of the Day: This Little Piggy
Sukanya Charuchandra | Sep 20, 2018
Recordings of electrical activity in porcine brains finds similarities to rodent neural tissue.
Long-Sought Hearing Channel Protein Found
Long-Sought Hearing Channel Protein Found
Abby Olena | Aug 22, 2018
After a decades-long pursuit, researchers have confirmed the identity of the pore of the mechanotransduction channel in vertebrates’ inner ear hair cells.
Computer Programs Sift Through Spikes in Nerve Cells’ Activity
Computer Programs Sift Through Spikes in Nerve Cells’ Activity
Ashley Yeager | May 1, 2018
Software that can separate signals from noise brings neuroscientists a step closer to understanding neurons’ patterns of communication.
Implanted Magnetic Probes Measure Brain Activity
Implanted Magnetic Probes Measure Brain Activity
Ruth Williams | Nov 1, 2017
Micrometer-size magnetrodes detect activity-generated magnetic fields within living brains.
Infographic: Reading the Mind’s Magnetism
Infographic: Reading the Mind’s Magnetism
Ruth Williams | Oct 31, 2017
Newly designed sensors detect the magnetic fields generated by electrical activity within cat brains.
Image of the Day: Make or Break a Habit
Image of the Day: Make or Break a Habit
The Scientist Staff | Sep 7, 2017
Deep within the forebrains of mice, scientists have identified an elusive cell type responsible for forming habits.
Robotic Patch Clamping Gains Eyes
Robotic Patch Clamping Gains Eyes
Diana Kwon | Aug 30, 2017
Two groups of scientists combined automation with two-photon microscopy to target and record specific neurons in living animals. 
New and Old Techniques in Modern Neuroscience
New and Old Techniques in Modern Neuroscience
Alison F. Takemura | Oct 1, 2016
Imaging and manipulating the brain has come a long way from electrodes and the patch clamp, though such traditional tools remain essential.
New Gecko-Inspired Adhesive
New Gecko-Inspired Adhesive
Jef Akst | Apr 6, 2016
Flexible patches of silicone that stick to skin and conduct electricity could serve as the basis for a new, reusable electrode for medical applications.
Top Technical Advances 2015
Top Technical Advances 2015
Kerry Grens | Dec 23, 2015
The Scientist’s choice of major improvements in imaging, optogenetics, single-cell analyses, and CRISPR
Wired Flower
Wired Flower
Karen Zusi | Nov 24, 2015
Researchers use a conducting polymer to construct circuits inside plant cuttings in a proof-of-concept study.
Identity-Shifting Brain Cells
Identity-Shifting Brain Cells
Ruth Williams | Sep 10, 2015
Cortical interneurons in mice exhibit activity-dependent alterations to their characteristic firing patterns.
Cutting the Wire
Cutting the Wire
Jeffrey M. Perkel | Dec 1, 2014
Optical techniques for monitoring action potentials
The Body Electric, 1840s
The Body Electric, 1840s
Jef Akst | Nov 1, 2014
Emil du Bois-Reymond’s innovations for recording electrical signals from living tissue set the stage for today’s neural monitoring techniques.
Retina Recordings
Retina Recordings
Ruth Williams | Oct 1, 2014
Scientists adapt an in vivo retina recorder for ex vivo use.
Cortical Computing
Cortical Computing
Abby Olena | Oct 28, 2013
A study shows that dendrites not only transmit information between neurons, but also process some of that information.