Alzheimer’s Risk Gene Paradoxically Protects Against Memory Loss
Alzheimer’s Risk Gene Paradoxically Protects Against Memory Loss
A new study links a variant of the apolipoprotein E gene called APOE ε4 to better memory in older age, even in the presence of amyloid plaques—a possible explanation for the variant’s persistence despite its association with an increased risk of Alzheimer’s disease.
Alzheimer’s Risk Gene Paradoxically Protects Against Memory Loss
Alzheimer’s Risk Gene Paradoxically Protects Against Memory Loss

A new study links a variant of the apolipoprotein E gene called APOE ε4 to better memory in older age, even in the presence of amyloid plaques—a possible explanation for the variant’s persistence despite its association with an increased risk of Alzheimer’s disease.

A new study links a variant of the apolipoprotein E gene called APOE ε4 to better memory in older age, even in the presence of amyloid plaques—a possible explanation for the variant’s persistence despite its association with an increased risk of Alzheimer’s disease.

gene variants
“Rogue” Protein Could Contribute to Humans’ High Cancer Rates
“Rogue” Protein Could Contribute to Humans’ High Cancer Rates
Asher Jones | Apr 1, 2021
A mutant protein called Siglec-XII may promote carcinoma progression in humans, but inactivation of its gene seems to avoid the problem, according to a study.
Genome Reveals Clues to Giraffes’ “Blatantly Strange” Body Shape
Genome Reveals Clues to Giraffes’ “Blatantly Strange” Body Shape
Amanda Heidt | Mar 19, 2021
The physiological demands of that long neck get support from a gene involved in strengthening bones and blood vessels, researchers find after inserting the sequence in mice.
Q&A: A New Tool for Ensuring Genetic Privacy
Q&A: A New Tool for Ensuring Genetic Privacy
Amanda Heidt | Nov 12, 2020
Gamze Gursoy and Mark Gerstein of Yale Medical School have developed a strategy for stripping identifying variants from functional genomic data, balancing privacy with utility.
<em>NPSR1</em> Variant Linked to Less Sleep in People: Study
NPSR1 Variant Linked to Less Sleep in People: Study
Emily Makowski | Oct 16, 2019
“Short sleeper” mice engineered to have the same sequence in the gene sleep less but show the same performance on memory tests as animals that sleep a normal amount.
Neuroscientist Rahul Desikan Dies
Neuroscientist Rahul Desikan Dies
Kerry Grens | Jul 19, 2019
He developed an MRI-based map of the human cortex, discovered genetic risk factors for neurodegenerative diseases, and wrote about his struggles with ALS.
More Autism Genes Identified
More Autism Genes Identified
Ashley Yeager | Oct 17, 2018
Researchers parse genes linked with intellectual disability and autism from those tied to autism alone.
NIH Plans to Enroll 1 Million People for Health Database
NIH Plans to Enroll 1 Million People for Health Database
Catherine Offord | May 3, 2018
The agency says it has taken various steps to ensure the privacy of participants’ data. 
Researchers Identify Gene Variants Linked to Synesthesia
Researchers Identify Gene Variants Linked to Synesthesia
Catherine Offord | Mar 5, 2018
A whole-genome analysis of people who experience color when they listen to sounds points to a handful of genes involved in neural development.
Genetic Risk Factors for Breast Cancer Identified
Genetic Risk Factors for Breast Cancer Identified
Ashley P. Taylor | Oct 23, 2017
Researchers identify 72 novel genetic variants associated with breast cancer risk.
Abundant Sequence Errors in Public Databases
Abundant Sequence Errors in Public Databases
Ruth Williams | Feb 16, 2017
A new algorithm reveals hoards of preparation-induced DNA mutations in publicly available human sequences.
Genetic Connections Among Human Traits
Genetic Connections Among Human Traits
Anna Azvolinsky | May 16, 2016
A study identifies genetic variants that are linked to multiple phenotypes.
Genetics of Educational Attainment?
Genetics of Educational Attainment?
Jef Akst | May 12, 2016
In a study of nearly 300,000 people, researchers identify 74 gene variants that are linked with how long subjects stayed in school.
A Tree  Takes Root
A Tree Takes Root
Ashley P. Taylor | Apr 1, 2016
Four apparently unrelated individuals share a common ancestor from whom they inherited a rare mutation that predisposed them to the cancer they share.
Death in the Dust
Death in the Dust
The Scientist Staff | Mar 31, 2016
Follow Michele Carbone as he tracks down the genetic and environmental drivers of mesothelioma and other cancers.
Disease-Linked Genes Questioned
Disease-Linked Genes Questioned
Jef Akst | Jan 6, 2016
Many patients with genetic variations linked to cardiac disorders do not exhibit any symptoms, raising concerns about the validity of incidental findings of genetic tests.
Domestication’s Downsides for Dogs
Domestication’s Downsides for Dogs
Ashley P. Taylor | Dec 21, 2015
The selection of traits suitable for human companionship may have dragged along some unfavorable alleles.
Autism in the Genes
Autism in the Genes
Jef Akst | Jul 22, 2014
Researchers determine that heritability outweighs non-genetic risk factors when it comes to the developmental disorder.
Genetic Deodorant
Genetic Deodorant
Jef Akst | Jan 18, 2013
People carrying a certain gene variant that dictates fresh underarms are less likely to wear antiperspirant.
New Genome Resource
Edyta Zielinska | Jul 11, 2012
Members of the Personal Genome Project have created software aimed at helping researchers tease apart genetic differences between individuals.