Illustration depicting DNA genetic engineering, purple background with white drawings of internal organs like liver, lung, kidney, brain, intestine, stomach and a red heart featuring two orange DNA helices being cut by labcoat-covered arms and hands, which are holding different instruments to cut the helices.

| 4 min read

Ancestry Bias Could Cause CRISPR Screens to Veer Off-target

Current CRISPR guide RNAs are designed based on European reference genomes, leading to false-negative results in cells from people with African ancestry.

A CRISPR-Cas platform uses microfluidic droplets, encasing CRISPR components and DNA barcodes, and injects individual droplets into zebrafish embryos. The embryos are raised and then researchers link phenotypes to genotypes by sequencing the barcodes.

| 1 min read

DNA Droplets in Motion Accelerate Gene Discovery

Learn How Multi-Gene Panels are Used to Find Hereditary Cancer

| 1 min read

Multi-Gene Panels in Hereditary Cancer: Cause for Caution?

genetic screens

multicolor DNA sequencing gel

Genetic Mutations Can Be Benign or Cancerous—a New Method to Differentiate Between Them Could Lead to Better Treatments

Ryan LayerandThe Conversation | | 5 min read

Learn About Variant Annotation in Hereditary Cancer

Assigning Meaning: Genetic Variant Interpretation in Hereditary Cancer

Qiagen | | 1 min read

The Scientist Speaks Podcast - Episode 10

The Scientist Creative Services Team | | 1 min read

Circulating Fetal Cells Sequenced for Prenatal Testing Study

Emily Makowski | | 3 min read

buccal swab brca brca1 brca2 genetic test cancer screening uspstf

New Guidelines Expand BRCA Screening

Ashley P. Taylor | | 2 min read

The Cancer Genes Needed for Immunotherapy Response

Anna Azvolinsky | | 4 min read

Massive RNAi Screens Probe for Genes Important to Cancer

Kerry Grens | | 3 min read

First Genetic Screen of Pigs Using ENU

Ashley Yeager | | 3 min read

Bioethicist and Law Professor Dies

Kerry Grens | | 2 min read

Page 1 of 2 - 16 Total Items

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The Biggest Breakthroughs in Cell Biology in 2025

From microglia reprogramming to immune cell-based diagnostics, 2025 was a big year for breakthroughs in cell biology.

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

Gollum, the extremely territorial character from The Lord of the Rings, famous for his line, “My precious,” sits on a rock, looking up.

The Gollum Effect: 44 Percent of Scientists Report Territorial Research Experiences

Survey data showed that hoarding research topics and resources, termed the Gollum effect, has a lasting impact on trainees and perpetuates a toxic research culture.

person doing the finger prick test for measuring blood glucose. A new noninvasive method could provide an alternative to such invasive blood tests.

Measuring Blood Sugar Without Painful Pricks? A New Test Scans Skin

Shining near-infrared light on a person’s skin helped scientists accurately track his blood glucose levels, offering a potential noninvasive way to monitor diabetes.

Multimedia

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Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.

December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

View this Issue

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Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Human iPSC-derived Models for Brain Disease Research

Human iPSC-derived Models for Neurodegenerative Disease Research

In this webinar, Jesús Tintos-Hernandez, Setsu Endoh-Yamagami, and Amaris Castañon will discuss the latest advances and innovations in neuroscience disease cell models.

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Exploring the Inflammatory Tumor Microenvironment

Within the tumor microenvironment, networks of cells and molecular signals form a dynamic landscape that drives disease progression.

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BRANDTECH® Scientific Announces Strategic Partnership with Copia Scientific to Strengthen Sales and Service of the BRAND® Liquid Handling Station (LHS)

This partnership will enable both companies to reach a broader range of customers, including those with more complex and specialized workflows

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Enter Our 2026 Top Innovations Contest

Submit a cutting-edge product or technology for the chance to be recognized as one of The Scientist’s 2026 Top Innovations.

Biotium Expands Tyramide Signal Amplification Portfolio with Brighter and More Stable Dyes for Enhanced Spatial Imaging

Biotium's new TyraMax™ Amplification Dyes and Kits are available with the widest selection of colors for spatial analysis

LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

Ten-year Agreement to Provide a Secure, AI-enabled Forensic Laboratory Information Management System Supporting DHS Forensic, Scientific, and Testing Services