Illustration of pink and blue DNA molecules.
Historic Adaptations May Now Make Us Susceptible to Disease
Researchers made the find using an algorithm that purportedly distinguishes between mutations that were selected for and those that came along for the ride by coincidence, a feat that has long eluded scientists.
Historic Adaptations May Now Make Us Susceptible to Disease
Historic Adaptations May Now Make Us Susceptible to Disease

Researchers made the find using an algorithm that purportedly distinguishes between mutations that were selected for and those that came along for the ride by coincidence, a feat that has long eluded scientists.

Researchers made the find using an algorithm that purportedly distinguishes between mutations that were selected for and those that came along for the ride by coincidence, a feat that has long eluded scientists.

gwas
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
A twisted and folded illustration of single-stranded RNA in front of a blue background.
Deficient RNA Editing Implicated in Inflammatory Disease 
Alejandra Manjarrez | Aug 5, 2022
Genetic variants that reduce the editing levels of double-stranded RNA are associated with autoimmune and immune-mediated conditions, a study finds.
Small Changes, Big Consequences
Small Changes, Big Consequences
Niki Spahich, PhD
To understand the mechanisms behind severe COVID-19, researchers identified common COVID-19 genetic risk variants that affect immune cell function.
genome sequence text on screen 
Q&A: Whole Genomes of 150,000 Britons Reveal Novel Genetic Variants
Sophie Fessl | Aug 5, 2022
Height and onset of menarche are among traits linked to previously unidentified genetic variants in noncoding regions of the human genome.
Illustration of scientists collaborating
How to Bring the Public into the Scientific Process
Amanda Heidt | Mar 14, 2022
A new wave of research is recruiting patients and other members of the public to serve as equal partners, bringing fresh perspectives to research on diseases and other conditions.
Uncovering Leprosy’s Genetic Recipe for Success
Uncovering Leprosy’s Genetic Recipe for Success
Nele Haelterman, PhD
Researchers identify what makes certain people more likely to contract leprosy than others.
Sunflowers, in visible spectrum on left half (yellow colors) and UV spectrum on right half (purple and white colors).
Sunflowers’ Bee-Attracting Ultraviolet Also Helps Retain Moisture
Natalia Mesa | Feb 8, 2022
The dual purposes of the plants’ hidden colors may conflict as the climate warms, authors of a new study suggest.
Colored Genetic Code DNA Molecule Structure stock photo
Genetic Risks for Depression Differ Between Ancestral Groups
Chloe Tenn | Oct 19, 2021
A large genome-wide association study in East Asians uncovers novel genetic links to depression, calling attention to the consequences of underrepresentation of non-European groups in genetic research data.
Discover Genetic Influences on the Immune Response
The Genetics Behind Immune Response Variability
The Scientist Creative Services Team
Researchers seek genomic clues to understand differences in the immune response to infection.
artistic drawing of neuron filled with tau proteins
Genes for Alcohol Use Disorder and Alzheimer’s Risk Overlap: Study
Emma Yasinski | Aug 24, 2021
Genetic, transcriptomic, and epigenetic data reveal molecular mechanisms tying these disorders to each other and to immune disfunction.
GWAS, psychotic disorder, mood disorder, Q&A, bipolar disorder, schizophrenia, depression, sex differences
Genetic Variants Tied to Sex Differences in Psychiatric Disorders
Amanda Heidt | Mar 31, 2021
The largest study of its kind identifies single nucleotide polymorphisms with disparate effects on men’s and women’s susceptibility to conditions such as bipolar disorder and schizophrenia.
polygenic risk score genetics genomics direct to consumer genome sequencing gwas
Researchers Develop Standards for Reporting Polygenic Risk Scores
Marcus A. Banks | Mar 17, 2021
Current reporting about the contribution of genetic variations to a person’s risk of disease is often incomplete and hard to interpret, according to the authors of a set of best practices for presenting such information.
Key Genes Related to Severe COVID-19 Infection Identified
Max Kozlov | Dec 14, 2020
Differences in the expression of genes associated with antiviral immunity and lung inflammation may contribute to a more serious COVID-19 infection.
Two Genetic Regions Linked with Severe COVID-19
Abby Olena | Jun 8, 2020
In a genome-wide association study, variants in both the ABO blood group locus and a cluster of genes on human chromosome 3 are more common among COVID-19 patients with respiratory failure than in the general population.
coronavirus covid-19 host genetics genome gwas samples genes susceptibility severe cases sars-cov-2
DNA Could Hold Clues to Varying Severity of COVID-19
Marla Broadfoot | Apr 17, 2020
Hundreds of scientists around the globe are launching studies in search of genes that could explain why some people fall victim to coronavirus infection while others escape relatively unscathed.
A New Way to Establish Cause and Effect in Epidemiology?
Rachael Moeller Gorman | Jan 1, 2020
A technique called Mendelian randomization is overturning the conclusions of observational studies in public health. But researchers question whether the method can overcome its fundamental limitations.
a map showing the country of Uganda
Study of Ugandan Genomes Yields Novel Variants, Health Links
Shawna Williams | Oct 31, 2019
The authors say their results demonstrate the global benefits of studying African genetics.
migration genetics uk wealth inequality education
Opinion: The Nature of Social Inequalities in Great Britain
Abdel Abdellaoui and Judy Luigjes | Oct 21, 2019
Regional differences in wealth in the UK are tied to genetic variants related to education—and migration is only widening the gap.
geneplaza how gay am i genetic gwas homosexual heterosexual same-sex sexual behavior
Scientists Seek to Kill Genetic Test for Same-Sex Attraction
Diana Kwon | Oct 17, 2019
Direct-to-consumer “How Gay Are You?” app sold by GenePlaza has been criticized for being misleading and irresponsible.