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a person pours whiskey into a glass held by another person, with a smoking cigar in a tray in front
Study of Millions Finds Genetic Links to Smoking and Drinking 
In the largest study of its kind, scientists find nearly 4,000 genetic variants that may predispose people to alcohol and tobacco use behaviors. 
Study of Millions Finds Genetic Links to Smoking and Drinking 
Study of Millions Finds Genetic Links to Smoking and Drinking 

In the largest study of its kind, scientists find nearly 4,000 genetic variants that may predispose people to alcohol and tobacco use behaviors. 

In the largest study of its kind, scientists find nearly 4,000 genetic variants that may predispose people to alcohol and tobacco use behaviors. 

gwas
A cross-section of a mouse hypothalamus, where cells of the arcuate nucleus are shown in bright green at the bottom.
Methylation in Young Brains May Be Key to Obesity: Mouse Study
Alejandra Manjarrez, PhD | Oct 19, 2022 | 4 min read
Epigenetic events, such as methylation, during early brain development in mice occur in genomic regions associated with BMI in humans, according to a new study.
White mice in a clear plastic cage
Different Genes Influence Lifespan in Male and Female Mice
Natalia Mesa, PhD | Sep 29, 2022 | 3 min read
Researchers say there may be similar, human genes whose effects on lifespan vary by sex.
Small Changes, Big Consequences
Small Changes, Big Consequences
Niki Spahich, PhD | 3 min read
To understand the mechanisms behind severe COVID-19, researchers identified common COVID-19 genetic risk variants that affect immune cell function.
Illustration of pink and blue DNA molecules.
Historic Adaptations May Now Make Us Susceptible to Disease
Dan Robitzski | Sep 16, 2022 | 5 min read
Researchers made the find using an algorithm that purportedly distinguishes between mutations that were selected for and those that came along for the ride by coincidence, a feat that has long eluded scientists.
Illustration showing a puzzle piece of DNA being removed
Large Scientific Collaborations Aim to Complete Human Genome
Brianna Chrisman and Jordan Eizenga | Sep 1, 2022 | 10+ min read
Thirty years out from the start of the Human Genome Project, researchers have finally finished sequencing the full 3 billion bases of a person’s genetic code. But even a complete reference genome has its shortcomings.
Uncovering Leprosy’s Genetic Recipe for Success
Uncovering Leprosy’s Genetic Recipe for Success
Nele Haelterman, PhD | 3 min read
Researchers identify what makes certain people more likely to contract leprosy than others.
A twisted and folded illustration of single-stranded RNA in front of a blue background.
Deficient RNA Editing Implicated in Inflammatory Disease 
Alejandra Manjarrez, PhD | Aug 5, 2022 | 3 min read
Genetic variants that reduce the editing levels of double-stranded RNA are associated with autoimmune and immune-mediated conditions, a study finds.
genome sequence text on screen 
Q&A: Whole Genomes of 150,000 Britons Reveal Novel Genetic Variants
Sophie Fessl, PhD | Aug 5, 2022 | 5 min read
Height and onset of menarche are among traits linked to previously unidentified genetic variants in noncoding regions of the human genome.
Discover Genetic Influences on the Immune Response
The Genetics Behind Immune Response Variability
The Scientist Creative Services Team | 1 min read
Researchers seek genomic clues to understand differences in the immune response to infection.
Illustration of scientists collaborating
How to Bring the Public into the Scientific Process
Amanda Heidt | Mar 14, 2022 | 10+ min read
A new wave of research is recruiting patients and other members of the public to serve as equal partners, bringing fresh perspectives to research on diseases and other conditions.
Sunflowers, in visible spectrum on left half (yellow colors) and UV spectrum on right half (purple and white colors).
Sunflowers’ Bee-Attracting Ultraviolet Also Helps Retain Moisture
Natalia Mesa, PhD | Feb 8, 2022 | 5 min read
The dual purposes of the plants’ hidden colors may conflict as the climate warms, authors of a new study suggest.
Colored Genetic Code DNA Molecule Structure stock photo
Genetic Risks for Depression Differ Between Ancestral Groups
Chloe Tenn | Oct 19, 2021 | 4 min read
A large genome-wide association study in East Asians uncovers novel genetic links to depression, calling attention to the consequences of underrepresentation of non-European groups in genetic research data.
artistic drawing of neuron filled with tau proteins
Genes for Alcohol Use Disorder and Alzheimer’s Risk Overlap: Study
Emma Yasinski | Aug 24, 2021 | 4 min read
Genetic, transcriptomic, and epigenetic data reveal molecular mechanisms tying these disorders to each other and to immune disfunction.
GWAS, psychotic disorder, mood disorder, Q&A, bipolar disorder, schizophrenia, depression, sex differences
Genetic Variants Tied to Sex Differences in Psychiatric Disorders
Amanda Heidt | Mar 31, 2021 | 5 min read
The largest study of its kind identifies single nucleotide polymorphisms with disparate effects on men’s and women’s susceptibility to conditions such as bipolar disorder and schizophrenia.
polygenic risk score genetics genomics direct to consumer genome sequencing gwas
Researchers Develop Standards for Reporting Polygenic Risk Scores
Marcus A. Banks | Mar 17, 2021 | 3 min read
Current reporting about the contribution of genetic variations to a person’s risk of disease is often incomplete and hard to interpret, according to the authors of a set of best practices for presenting such information.
Key Genes Related to Severe COVID-19 Infection Identified
Max Kozlov | Dec 14, 2020 | 3 min read
Differences in the expression of genes associated with antiviral immunity and lung inflammation may contribute to a more serious COVID-19 infection.
Two Genetic Regions Linked with Severe COVID-19
Abby Olena, PhD | Jun 8, 2020 | 4 min read
In a genome-wide association study, variants in both the ABO blood group locus and a cluster of genes on human chromosome 3 are more common among COVID-19 patients with respiratory failure than in the general population.
coronavirus covid-19 host genetics genome gwas samples genes susceptibility severe cases sars-cov-2
DNA Could Hold Clues to Varying Severity of COVID-19
Marla Broadfoot | Apr 17, 2020 | 4 min read
Hundreds of scientists around the globe are launching studies in search of genes that could explain why some people fall victim to coronavirus infection while others escape relatively unscathed.
A New Way to Establish Cause and Effect in Epidemiology?
Rachael Moeller Gorman | Jan 1, 2020 | 7 min read
A technique called Mendelian randomization is overturning the conclusions of observational studies in public health. But researchers question whether the method can overcome its fundamental limitations.
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