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How Oxygen Affects Cellular Function
Discover reasons for avoiding low oxygen levels in cell cultures.
How Oxygen Affects Cellular Function
How Oxygen Affects Cellular Function

Discover reasons for avoiding low oxygen levels in cell cultures.

Discover reasons for avoiding low oxygen levels in cell cultures.

in vitro
Pink rat pups piled on top of each other.
Rat Sperm Generated from Stem Cells
Alejandra Manjarrez | Apr 7, 2022
Researchers report they were able to make functional sperm in a dish, a feat previously only possible for mice.
Human large intestine tissue under microscope view
Mini-Guts to the Rescue: Introducing 3-D Organoid Cell Cultures
The Scientist Creative Services Team and MilliporeSigma | Jan 19, 2022
A cost-effective 3-D organoid biobank provides a versatile translational research tool.
stem cell culture
An Optimized Culture Medium for Induced Pluripotent Stem Cells
The Scientist Creative Services Team in collaboration with Bio-Techne | Dec 10, 2021
An animal component-free culture medium provides a safe and robust alternative for maintaining induced pluripotent stem cells.
Lizard on glass tank
Engineered Stem Cells Grant Geckos “Perfectly” Regenerated Tails
Chloe Tenn | Nov 5, 2021
Geckos injected with neural stem cells modified to block cartilage growth developed the skeletal and nervous components normally lacking from regrown tails.
ethics, bioethics, brain organoid, chimera, cell transplant, Q&A, report, NIH, NAS, neuroscience, Techniques, disease & medicine, immunology, psychiatric conditions
New Report Dissects Ethics of Emerging Human Brain Cell Models
Amanda Heidt | Apr 12, 2021
The National Academies’ report touches on ethical issues raised by new technologies such as brain organoids and human-animal chimeras, and suggests that current regulatory oversight is sufficient.
3-D Treatment
Tumor Organoids Hold Promise for Personalizing Cancer Therapy
Jef Akst | Jul 15, 2019
The three-dimensional cell cultures are still in the development phase, but researchers are excited about their use to predict patients’ responses to various treatment options.
Blood Vessels Grown in a Petri Dish Closely Resemble Human Ones
Catherine Offord | Jan 18, 2019
The lab-made organoids are fully functional, the team reports, and could aid the study of vascular-related diseases such as diabetes.
New Technique Limits CRISPR-Cas9 Off-Target Mutations
Abby Olena | Sep 12, 2018
A mouse study details a method called VIVO that predicts the accuracy of any guide RNA.
Researchers Develop a Drug Against the Common Cold
Catherine Offord | May 15, 2018
In an in vitro study, the compound completely blocked the replication of rhinoviruses.
Colorblindness Study Reveals Unexpected Way to Make Blood Vessels
Ashley Yeager | May 1, 2018
Researchers stumbled across the connection while searching for ways to reduce vision problems in people with achromatopsia.
Image of the Day: Everybody Vomits
The Scientist Staff | Aug 31, 2017
In a process known as vomocytosis, macrophages swallow pathogens whole only to spew them back out later, unharmed.
Chloroquine Protects Against Zika In Vitro
Marcia Triunfol | May 12, 2016
The antimalarial drug reduces the number of infected Vero and human brain microvascular endothelial cells—among other cell types—in culture, researchers report in a preprint.
Next Generation: Toward Synthetic Neural Tissue
Catherine Offord | Apr 1, 2016
Scientists produce a tissue-like material containing hundreds of light-activated compartments that transmits an electrical signal when illuminated.
Antidepressant Exerts Epigenetic Changes
Anna Azvolinsky | Nov 25, 2015
Molecular markers could aid researchers’ assessment of patient response to the drug.
 
Organoid Biobank
Kerry Grens | May 11, 2015
From the tissue of numerous colon cancer patients, researchers build 3-D cultures of tumors.
Seeded by Weeds
K. John Morrow Jr. | May 1, 2015
More than 50 years after cross-contamination of cultured cell lines was recognized, the problem continues to plague the scientific community.
Culturing Changes Cells
Kerry Grens | Feb 3, 2015
Within days of their transfer to a dish, a certain epigenetic mark vanishes from mouse cells.
Homo Minutus
Jyoti Madhusoodanan | Dec 1, 2014
A miniature platform with multiple organ-on-a-chip constructs aims to speed up drug discovery—and create better transplants for patients.
Desktop Human
Jyoti Madhusoodanan | Nov 30, 2014
Meet the researchers behind ATHENA, the project that aims to create a system of linked model human organs that may revolutionize drug development.