iPSC
Nailing Down HAR Function
Nailing Down HAR Function
Katherine S. Pollard | Jul 31, 2016
A remaining challenge in the study of human accelerated regions (HARs) is establishing their specific functions during development and other biological processes.
Stem Cells for Personalized Pain Therapy Testing
Stem Cells for Personalized Pain Therapy Testing
Anna Azvolinsky | Apr 21, 2016
Using patient-derived stem cells, researchers create laboratory neuron models that reflect a patient’s response to a pain drug.
Low Mutation Rate in iPSCs
Low Mutation Rate in iPSCs
Catherine Offord | Apr 11, 2016
The mutation rate in induced pluripotent stem cells is 10 times lower than in somatic cells, scientists show.
iPSCs and Cancer Risk
iPSCs and Cancer Risk
Catherine Offord | Feb 24, 2016
Reprogramming adult human cells into stem cells in vitro does not generate harmful mutations, scientists report.
CRISPR Corrects Retinal Disease Mutation
CRISPR Corrects Retinal Disease Mutation
Catherine Offord | Jan 28, 2016
Patient-derived stem cells containing a genetic mutation leading to blindness can be successfully edited using CRISPR/Cas9, researchers show.
Pluripotency Bots
Pluripotency Bots
Kate Yandell | Jan 1, 2016
A tour of efforts to automate the production and differentiation of induced pluripotent stem cells
Probing Down Syndrome with Mini Brains
Probing Down Syndrome with Mini Brains
Bob Grant | Oct 20, 2015
Researchers create cerebral organoids using induced pluripotent stem cells from patient skin cells and characterize protein-expression changes linked to cognitive impairment.
Electromagnetism Promotes Pluripotency: Study
Electromagnetism Promotes Pluripotency: Study
Kerry Grens | Oct 23, 2014
A paper published last month claims that electromagnetic exposure facilitates cell reprogramming, but some scientists question the evidence.
Stem Cell Trial for Eye Disease Commences
Stem Cell Trial for Eye Disease Commences
Jef Akst | Sep 12, 2014
Researchers at the RIKEN Center for Developmental Biology will treat the first patient in its clinical trial testing an induced pluripotent stem cell-based treatment for age-related macular degeneration.
Neural Stem Cells Sprout Long Axons
Neural Stem Cells Sprout Long Axons
Jyoti Madhusoodanan | Aug 7, 2014
Early neurons reprogrammed from human skin cells show unprecedented axonal growth in a rat model of spinal cord injury.