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Nailing Down HAR Function
Katherine S. Pollard | Jul 31, 2016
A remaining challenge in the study of human accelerated regions (HARs) is establishing their specific functions during development and other biological processes.
Stem Cells for Personalized Pain Therapy Testing
Anna Azvolinsky | Apr 21, 2016
Using patient-derived stem cells, researchers create laboratory neuron models that reflect a patient’s response to a pain drug.
Low Mutation Rate in iPSCs
Catherine Offord | Apr 11, 2016
The mutation rate in induced pluripotent stem cells is 10 times lower than in somatic cells, scientists show.
iPSCs and Cancer Risk
Catherine Offord | Feb 24, 2016
Reprogramming adult human cells into stem cells in vitro does not generate harmful mutations, scientists report.
CRISPR Corrects Retinal Disease Mutation
Catherine Offord | Jan 28, 2016
Patient-derived stem cells containing a genetic mutation leading to blindness can be successfully edited using CRISPR/Cas9, researchers show.
Kate Yandell | Jan 1, 2016
A tour of efforts to automate the production and differentiation of induced pluripotent stem cells
Probing Down Syndrome with Mini Brains
Bob Grant | Oct 20, 2015
Researchers create cerebral organoids using induced pluripotent stem cells from patient skin cells and characterize protein-expression changes linked to cognitive impairment.
Electromagnetism Promotes Pluripotency: Study
Kerry Grens | Oct 23, 2014
A paper published last month claims that electromagnetic exposure facilitates cell reprogramming, but some scientists question the evidence.
Stem Cell Trial for Eye Disease Commences
Jef Akst | Sep 12, 2014
Researchers at the RIKEN Center for Developmental Biology will treat the first patient in its clinical trial testing an induced pluripotent stem cell-based treatment for age-related macular degeneration.
Neural Stem Cells Sprout Long Axons
Jyoti Madhusoodanan | Aug 7, 2014
Early neurons reprogrammed from human skin cells show unprecedented axonal growth in a rat model of spinal cord injury.