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Donor Stem Cells Improve Cardiac Function
Kerry Grens | Oct 12, 2016
After a heart attack, monkeys given induced pluripotent stem cell–derived cardiomyocytes show more regeneration in the organ, but with risks.
Stem Cells Made Waves in Biology and Medicine
Karen Zusi | Oct 1, 2016
Since their introduction to the lab, pluripotent stem cells have gone from research tool to therapeutic, but the journey has been rocky.
Thirty Years of Progress
Staff | Oct 1, 2016
published its first issue in October 1986, life-science research has transformed from a manual and often tedious task to a high-tech, largely automated process of unprecedented efficiency.
Toward Preventing Transplant Rejection with Immunologically Matched Stem Cells
Ruth Williams | Sep 15, 2016
Matching the immunological characteristics of donor retinal cells to those of the recipient can reduce the chance of rejection.
Nailing Down HAR Function
Katherine S. Pollard | Jul 31, 2016
A remaining challenge in the study of human accelerated regions (HARs) is establishing their specific functions during development and other biological processes.
Stem Cells for Personalized Pain Therapy Testing
Anna Azvolinsky | Apr 21, 2016
Using patient-derived stem cells, researchers create laboratory neuron models that reflect a patient’s response to a pain drug.
Low Mutation Rate in iPSCs
Catherine Offord | Apr 11, 2016
The mutation rate in induced pluripotent stem cells is 10 times lower than in somatic cells, scientists show.
iPSCs and Cancer Risk
Catherine Offord | Feb 24, 2016
Reprogramming adult human cells into stem cells in vitro does not generate harmful mutations, scientists report.
CRISPR Corrects Retinal Disease Mutation
Catherine Offord | Jan 28, 2016
Patient-derived stem cells containing a genetic mutation leading to blindness can be successfully edited using CRISPR/Cas9, researchers show.
Kate Yandell | Jan 1, 2016
A tour of efforts to automate the production and differentiation of induced pluripotent stem cells