New Protocol Advances Toward Lab-Made Universal Red Blood Cells
New Protocol Advances Toward Lab-Made Universal Red Blood Cells
Researchers report a new way of generating the cells from induced pluripotent stem cells in hopes they will one day be used in blood transfusions.
New Protocol Advances Toward Lab-Made Universal Red Blood Cells
New Protocol Advances Toward Lab-Made Universal Red Blood Cells

Researchers report a new way of generating the cells from induced pluripotent stem cells in hopes they will one day be used in blood transfusions.

Researchers report a new way of generating the cells from induced pluripotent stem cells in hopes they will one day be used in blood transfusions.

iPSC
New iPSC Culture Medium Promises Weekends Off at Low Costs
New iPSC Culture Medium Promises Weekends Off at Low Costs
Katarina Zimmer | Jan 20, 2020
Biologists have published a DIY recipe for human induced pluripotent stem cell maintenance, which they estimate costs 3 percent of commercial media prices.
Gene Editing Makes Cells Evade Immune Attack In Vitro
Gene Editing Makes Cells Evade Immune Attack In Vitro
Emma Yasinski | Dec 12, 2019
To advance the possibility of off-the-shelf cardiac cell therapies, scientists devise an engineered cardiac stem cell that avoids stimulating a detrimental immune attack.
Oct4, Considered Vital for Creating iPSCs, Actually Isn’t Needed
Oct4, Considered Vital for Creating iPSCs, Actually Isn’t Needed
Emma Yasinski | Nov 8, 2019
Dropping the transcription factor from the four so-called Yamanaka factors reduces the efficiency of inducing the production of stem cells, but the resulting cells are of greater quality.
Woman Receives First Corneal Transplant Made from iPS Cells
Woman Receives First Corneal Transplant Made from iPS Cells
Emily Makowski | Sep 3, 2019
The patient’s vision has improved since the procedure, and her cornea remains clear.
Clinical Trial Underway for a Natural Killer Cell Therapy
Clinical Trial Underway for a Natural Killer Cell Therapy
Chia-Yi Hou | May 7, 2019
The cells, derived from induced pluripotent stem cells, are in testing as an immunotherapy for cancer patients with solid tumors.
Bioethicists Concerned over Japan’s Chimera Embryo Regulations
Bioethicists Concerned over Japan’s Chimera Embryo Regulations
Katarina Zimmer | Apr 4, 2019
Many researchers see the move to relax the rules as a welcome change, yet some are worried the revisions don’t take public concerns enough into consideration.
Opinion: Ethical Challenges in Using iPS Cells to Treat Paralysis
Opinion: Ethical Challenges in Using iPS Cells to Treat Paralysis
John D. Loike, Martin Grumet | Mar 7, 2019
Uncertainties about the cells’ risk profiles and the potential for hyping unproven therapies mean scientists and the media must tread carefully.
Japan Approves iPS Cell Therapy Trial for Spinal Cord Injury
Japan Approves iPS Cell Therapy Trial for Spinal Cord Injury
Catherine Offord | Feb 18, 2019
The treatment will be tested in a handful of patients who suffered nerve damage in sports or traffic accidents.
The Biggest Science News of 2018
The Biggest Science News of 2018
Kerry Grens | Dec 27, 2018
From disastrous scientific setbacks to the upending of scientific dogma and the end of a 40-year search for a protein
Increasing Number of iPS Cell Therapies Tested in Clinical Trials
Increasing Number of iPS Cell Therapies Tested in Clinical Trials
Katarina Zimmer | Nov 28, 2018
Since their discovery in 2006, induced pluripotent stem cells have been poised to reprogram regenerative medicine. Twelve years on, here’s how far they’ve come.
Parkinson’s Patient Transplanted with Neurons Derived from iPSCs
Parkinson’s Patient Transplanted with Neurons Derived from iPSCs
Ashley P. Taylor | Nov 14, 2018
This is the first time researchers have tested the use of the reprogrammed stem cells in the human brain.
First iPS Cell Trial for Heart Disease Raises Excitement, Concern
First iPS Cell Trial for Heart Disease Raises Excitement, Concern
Katarina Zimmer | Aug 31, 2018
Without knowing the cells’ mechanism of action, researchers question the best way to administer them to patients.
Trial Launched to Treat Parkinson’s with Reprogrammed Stem Cells
Trial Launched to Treat Parkinson’s with Reprogrammed Stem Cells
Diana Kwon | Jul 31, 2018
Surgeons will inject approximately 5 million dopamine-producing progenitor cells into patients’ brains.
Stem Cell Vaccine Protects Mice From Cancer
Stem Cell Vaccine Protects Mice From Cancer
Ruth Williams | Feb 15, 2018
Stem cells and cancer cells have enough molecular similarities that the former can be used to trigger immunity against the latter.
Stem Cells Made by Modifying the Epigenome with CRISPR
Stem Cells Made by Modifying the Epigenome with CRISPR
Abby Olena | Jan 25, 2018
Researchers use the technique to turn on Oct4 or Sox2 in mouse embryonic fibroblasts and convert them into pluripotent cells. 
Coriell Institute CEO Dies
Coriell Institute CEO Dies
Kerry Grens | Jan 4, 2018
Michael Christman oversaw the organization’s well-known biobank and pioneered a personalized medicine initiative.
Researchers Make Knockout Stem Cell Lines in One Step
Researchers Make Knockout Stem Cell Lines in One Step
Ruth Williams | Dec 1, 2017
Combining gene editing and stem-cell induction improves efficiency of functional genetic analyses.