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A Fasting-Mimicking Diet Thwarts Breast Cancer in Mice
A Fasting-Mimicking Diet Thwarts Breast Cancer in Mice
Coupling a diet low in calories, sugar, and protein with existing cancer drugs treats triple-negative breast cancer in mice, and low blood glucose is associated with better cancer outcomes in human patients.
Coupling a diet low in calories, sugar, and protein with existing cancer drugs treats triple-negative breast cancer in mice, and low blood glucose is associated with better cancer outcomes in human patients.
kinase
The Bigger Protein Picture of Designing Parkinson’s Therapeutics
Deanna MacNeil, PhD | Feb 13, 2023 | 3 min read
Researchers highlight protein structure considerations for designing inhibitors that target familial Parkinson’s disease mutations.
Characterizing Kinases for Therapeutics Targeting Innate Immunity
BellBrook Labs | May 17, 2022 | 1 min read
Universal kinase assays can quickly and effectively screen and triage novel hits.
Phosphorylation at the Flick of a Switch
Ruth Williams | May 1, 2017 | 2 min read
Incorporating light-controlled dimerization domains into kinases provides tight regulation of these enzymes.
Infographic: Enzymes Controlled by Light
Ruth Williams | Apr 30, 2017 | 1 min read
Custom-designed kinases have built-in switches that act as gatekeepers for the enzymes' active sites.