Using sgRNA libraries for target identification and validation during drug discovery

Experience the past, present, and future of CRISPR technology.

Snails with a gene knocked out by CRISPR grow with their shells coiling in the opposite direction.

Researchers identified a gene in mosquitoes that moderates their susceptibility to malaria parasite infection. 

Researchers use CRISPR/Cas9 to screen for noncoding elements in the human genome.

Two research groups have developed a database of human gene knockouts generated from the new genome editing technology.  

Knocking down a single gene spurs pronounced secondary effects in the yeast genome.

A snapshot of the most highly ranked articles in microbiology and related areas, from Faculty of 1000.