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Microglia and glial cells
CRISPR-Ready Cells for Target Discovery 
A new iPSC-derived cellular tool with built-in Cas9 expression enables high efficiency knockout screening for drug target identification and validation.
CRISPR-Ready Cells for Target Discovery 
CRISPR-Ready Cells for Target Discovery 

A new iPSC-derived cellular tool with built-in Cas9 expression enables high efficiency knockout screening for drug target identification and validation.

A new iPSC-derived cellular tool with built-in Cas9 expression enables high efficiency knockout screening for drug target identification and validation.

knockout

Optimizing Arrayed CRISPR Screens
A Guide for Optimizing Arrayed CRISPR Screens
Synthego | Feb 16, 2022 | 1 min read
Using sgRNA libraries for target identification and validation during drug discovery
Lizard on glass tank
Engineered Stem Cells Grant Geckos “Perfectly” Regenerated Tails
Chloe Tenn | Nov 5, 2021 | 4 min read
Geckos injected with neural stem cells modified to block cartilage growth developed the skeletal and nervous components normally lacking from regrown tails.
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Introduction to CRISPR Genome Editing
Synthego | Sep 10, 2021 | 1 min read
Experience the past, present, and future of CRISPR technology.
snail shell coil coiling direction knockout CRISPR
Image of the Day: Lefties
Chia-Yi Hou | May 15, 2019 | 1 min read
Snails with a gene knocked out by CRISPR grow with their shells coiling in the opposite direction.
Image of the Day: Glowing Larva
The Scientist and The Scientist Staff | Mar 9, 2018 | 1 min read
Researchers identified a gene in mosquitoes that moderates their susceptibility to malaria parasite infection. 
Finding Enhancers with CRISPR
Anna Azvolinsky | Jan 11, 2016 | 3 min read
Researchers use CRISPR/Cas9 to screen for noncoding elements in the human genome.
CRISPR Creates Knockout Libraries
Kerry Grens | Dec 16, 2013 | 2 min read
Two research groups have developed a database of human gene knockouts generated from the new genome editing technology.  
One Gene, Two Mutations
Tracy Vence | Nov 5, 2013 | 2 min read
Knocking down a single gene spurs pronounced secondary effects in the yeast genome.
Top 7 in Microbiology
Megan Scudellari | Jul 26, 2011 | 3 min read
A snapshot of the most highly ranked articles in microbiology and related areas, from Faculty of 1000.
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