Proteins interact with DNA to regulate many vital processes in cells. Nearly 40 years ago, researchers developed a way to map these molecular connections.
Proteins interact with DNA to regulate many vital processes in cells. Nearly 40 years ago, researchers developed a way to map these molecular connections.
Proteins interact with DNA to regulate many vital processes in cells. Nearly 40 years ago, researchers developed a way to map these molecular connections.
Researchers developed a “test tube” so tiny that it can hold a single cell. These vials enabled them to connect protein secretion levels with surface markers and transcriptome data from the same cell.
By coloring different organelles simultaneously, cell painting allows scientists to pick up subtle changes in cell function in response to drugs and other perturbations.
The method, dubbed “DIANA,” could transform neuroscientists’ understanding of how the brain works, researchers say—though for now, it’s only been tested in anesthetized mice.
A research group argues that a species’ number of neurons, rather than brain volume, should serve as indicator of cognitive capacity when studying brain evolution, but some experts voice doubts.
Stable, long-term cell lines will enable scientists to study everything from coral bleaching to biomineralization, knowledge that may help protect corals from ongoing climate change.
Emmanuelle Charpentier and Jennifer Doudna reprogrammed the bacterial immune response into one of the most popular tools for genetics and molecular biology.