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Analyze Single-Stranded Oligonucleotide Purity
Analyzing Oligonucleotide Purity with Capillary Electrophoresis
Identify small impurities introduced by oligonucleotide synthesis prior to experimentation.
Analyzing Oligonucleotide Purity with Capillary Electrophoresis
Analyzing Oligonucleotide Purity with Capillary Electrophoresis

Identify small impurities introduced by oligonucleotide synthesis prior to experimentation.

Identify small impurities introduced by oligonucleotide synthesis prior to experimentation.

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oligonucleotides

A white lab mouse peers over the wall of a sprawling maze
Bacterial Metabolite May Regulate Cognition in Mice
Sophie Fessl, PhD | Jun 3, 2022 | 3 min read
Microbes in the gut influence the death of support cells in the brain by producing isoamylamine, a study suggests.
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Customized Commercial Molecular Assay Development
Thermo Fisher Scientific | Mar 23, 2022 | 1 min read
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Accelerating Drug Discovery: Focus on Nucleic Acid Therapeutics
Thermo Fisher Scientific | Sep 2, 2021 | 1 min read
Researchers develop strategies to prevent and treat diseases with nucleic acid therapies.
Red blood vessels that decrease in diameter as they radiate outward are pictured on a pink and white surface
Antisense Oligonucleotides Cross Rodents’ Blood-Brain Barrier
Abby Olena, PhD | Aug 18, 2021 | 3 min read
RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.
Technique Talk: Troubleshooting Quantitative PCR (qPCR)
The Scientist’s Creative Services Team | Jan 18, 2021 | 5 min read
In this workshop, you will learn about the critical factors that ensure qPCR accuracy and success.
Understanding and Optimizing PCR
The Scientist’s Creative Services Team | Sep 25, 2020 | 1 min read
Do you know how to get the most out of your PCR reactions?
Breakthrough Prizes Recognize Aneuploidy Researcher, Biochemist
Catherine Offord | Oct 18, 2018 | 2 min read
This year’s winners also include the developers of nusinersen, an oligonucleotide therapeutic for spinal muscular atrophy.
Custom-Made Molecules
Ruth Williams | Aug 20, 2017 | 3 min read
A new prototype machine can make the biological molecules of one’s choice from digital DNA sequences.
FDA Approves First Treatment for Spinal Muscular Atrophy
Ben Andrew Henry | Dec 27, 2016 | 1 min read
The oligonucleotide therapeutic will soon be available in the U.S.
Oligonucleotide Therapeutics Near Approval
Catherine Offord | Dec 1, 2016 | 8 min read
Successful late-stage clinical trials could mark the maturation of a new drug development platform, but the path to commercialization is not without hurdles.
Speaking of Neuroscience
Jef Akst and Mary Beth Aberlin | Nov 18, 2016 | 2 min read
A selection of notable quotes from the annual Society for Neuroscience meeting
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