Microbes in the gut influence the death of support cells in the brain by producing isoamylamine, a study suggests.

Explore the latest in nucleic acid amplification.

Researchers develop strategies to prevent and treat diseases with nucleic acid therapies.

RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.

This year’s winners also include the developers of nusinersen, an oligonucleotide therapeutic for spinal muscular atrophy.

A new prototype machine can make the biological molecules of one’s choice from digital DNA sequences.

The oligonucleotide therapeutic will soon be available in the U.S.

Successful late-stage clinical trials could mark the maturation of a new drug development platform, but the path to commercialization is not without hurdles.

A selection of notable quotes from the annual Society for Neuroscience meeting