A white lab mouse peers over the wall of a sprawling maze
Bacterial Metabolite May Regulate Cognition in Mice
Microbes in the gut influence the death of support cells in the brain by producing isoamylamine, a study suggests.
Bacterial Metabolite May Regulate Cognition in Mice
Bacterial Metabolite May Regulate Cognition in Mice

Microbes in the gut influence the death of support cells in the brain by producing isoamylamine, a study suggests.

Microbes in the gut influence the death of support cells in the brain by producing isoamylamine, a study suggests.

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oligonucleotides
Red blood vessels that decrease in diameter as they radiate outward are pictured on a pink and white surface
Antisense Oligonucleotides Cross Rodents’ Blood-Brain Barrier
Abby Olena | Aug 18, 2021
RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes.
Breakthrough Prizes Recognize Aneuploidy Researcher, Biochemist
Catherine Offord | Oct 18, 2018
This year’s winners also include the developers of nusinersen, an oligonucleotide therapeutic for spinal muscular atrophy.
Technique Talk: Troubleshooting Quantitative PCR (qPCR)
The Scientist Creative Services Team | Jan 18, 2021
In this workshop, you will learn about the critical factors that ensure qPCR accuracy and success.
Custom-Made Molecules
Ruth Williams | Aug 20, 2017
A new prototype machine can make the biological molecules of one’s choice from digital DNA sequences.
FDA Approves First Treatment for Spinal Muscular Atrophy
Ben Andrew Henry | Dec 27, 2016
The oligonucleotide therapeutic will soon be available in the U.S.
Understanding and Optimizing PCR
The Scientist Creative Services Team | Sep 25, 2020
Do you know how to get the most out of your PCR reactions?
Oligonucleotide Therapeutics Near Approval
Catherine Offord | Dec 1, 2016
Successful late-stage clinical trials could mark the maturation of a new drug development platform, but the path to commercialization is not without hurdles.
Speaking of Neuroscience
Jef Akst, Mary Beth Aberlin | Nov 18, 2016
A selection of notable quotes from the annual Society for Neuroscience meeting