oncogene
First Direct-to-Consumer BRCA Test Authorized by FDA
First Direct-to-Consumer BRCA Test Authorized by FDA
Kerry Grens | Mar 6, 2018
The agency gave personal genomics company 23andMe the green light to screen samples for breast cancer–related genetic mutations.
Study Raises Questions About Patient-Derived Xenografts
Study Raises Questions About Patient-Derived Xenografts
Ashley P. Taylor | Oct 10, 2017
When transplanted into mice, tumor genomes evolve differently than they do in patients, study finds.
Pradeep Chaluvally-Raghavan: Curious about Cancer
Pradeep Chaluvally-Raghavan: Curious about Cancer
Jef Akst | Apr 1, 2016
Instructor, Department of Systems Biology, University of Texas MD Anderson Cancer Center. Age: 38
MYC Helps Cancer Hide
MYC Helps Cancer Hide
Anna Azvolinsky | Mar 10, 2016
The transcriptional regulator dampens the immune system’s ability to elicit an antitumor response, a study shows.
Influential Cancer Biologist Dies
Influential Cancer Biologist Dies
Kerry Grens | Aug 24, 2015
Chris Marshall, who pieced together a critical signaling pathway involved in cancer, has passed away at age 66.
Professional Marksman
Professional Marksman
Anna Azvolinsky | Apr 1, 2015
Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.
Setbacks and Great Leaps
Setbacks and Great Leaps
Sue Armstrong | Apr 1, 2015
The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.
Two-Faced RNAs
Two-Faced RNAs
Kerry Grens | Apr 1, 2015
The same microRNAs can have opposing roles in cancer.
Book Excerpt from <em>p53</em>
Book Excerpt from p53
Sue Armstrong | Apr 1, 2015
In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.
Resisting Cancer
Resisting Cancer
George Klein | Apr 1, 2015
If one out of three people develops cancer, that means two others don’t. Understanding why could lead to insights relevant to prevention and treatment.