The agency gave personal genomics company 23andMe the green light to screen samples for breast cancer–related genetic mutations.

When transplanted into mice, tumor genomes evolve differently than they do in patients, study finds.

Instructor, Department of Systems Biology, University of Texas MD Anderson Cancer Center. Age: 38

The transcriptional regulator dampens the immune system’s ability to elicit an antitumor response, a study shows.

Chris Marshall, who pieced together a critical signaling pathway involved in cancer, has passed away at age 66.

The same microRNAs can have opposing roles in cancer.

The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.

Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.

In Chapter 12, "Of Mice and Men," author Sue Armstrong recounts the point at which researchers moved from working with p53 in tissue culture to studying the gene in animal models.