oncogene

Mouse models mimicking the transition from a common form of lung cancer to a more aggressive one may help scientists develop future strategies to prevent this transformation.

In this webinar, Özgen Deniz and Christina Leslie will discuss how epigenetic regulation affects oncogenesis.

Engineered bacteria sound the alarm on a common oncogenic mutation.

Learn how researchers establish new technologies such as liquid biopsies and targeted biomarker detection to further enhance precision oncology.

Synonymous mutations have long been ignored in cancer studies since they don’t affect the amino acid sequences of proteins. But research increasingly reveals that they can have disease-driving effects.

Rounds of trial-and-error exploring the layer of cells covering the ovary leave open questions about stem cells that are associated with ovarian cancer.

Guidelines for maintaining human cells grown ex vivo

In the last decade, researchers have come to realize that tumors harbor bits of extrachromosomal DNA that can drive malignancy.

Researchers are uncovering how circular bits of DNA found in some cancer cells can help tumors evolve and kill.

Best known as a cell cycle regulator, p53 signaling mediates pro and anti-cancer immune responses as well

The Harvard Medical School researcher’s work on the genetic basis of protein coding and production led him to make groundbreaking discoveries in immunology, molecular biology, and cancer genetics.

The agency gave personal genomics company 23andMe the green light to screen samples for breast cancer–related genetic mutations.

When transplanted into mice, tumor genomes evolve differently than they do in patients, study finds.

Instructor, Department of Systems Biology, University of Texas MD Anderson Cancer Center. Age: 38

The transcriptional regulator dampens the immune system’s ability to elicit an antitumor response, a study shows.

Chris Marshall, who pieced together a critical signaling pathway involved in cancer, has passed away at age 66.

Charles Sawyers, who began his research career just as the genetic details of human oncogenes were emerging, codeveloped Gleevec, the quintessential targeted cancer therapy.

The tale of p53, a widely studied tumor suppressor gene, illustrates the inventiveness of researchers who turn mishaps into discoveries.

The same microRNAs can have opposing roles in cancer.