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An illustration depicting the mechanism of the Crunch cell targeting system developed by researchers at Kyoto University. A blue silhouette of a person stands on the left. On the right is a magnified image of inside the body, where purple malignant cells have yellow proteins on their surface. A green adaptor protein depicted as being attracted to the yellow proteins is flying to the cells, while an orange phagocyte is attached to the adaptor protein.
| 2 min read
Researchers modified a protein in the cell elimination pathway to create a targeted system for destroying disease-causing cells, called Crunch.

phagocytosis

Microscopy image of a hair follicle shaft with clusters of orange debris surrounded by a group of green cells. Purple cells surround the hair root.

Stem Cells Dine on Dying Neighbors to Keep Tissues Fit 

Epithelial cells and fungal spores are marked with fluorescent dyes. Cells have an irregular shape and are shown in green and blue colors. Spores are spherical in shape and are labeled green if they are surrounded by p11 protein. A protein in mature phagosomes is labeled violet.

Fungal Spores Hijack a Host Protein to Escape Death

Illustration showing the path result of Eukaryogenesis

Infographic: Evolutionary Leaps Leading to Modern Eukaryotes

A microscope image of Legionellales bacteria infecting a protozoan

Ancestral Bacteria May Have Invaded Early Eukaryotic Cells

The adaptive and innate immune responses collaborate to attack T-cell resistant cancer cells

LabTalk Podcast - Phagocidal Macrophages: A New Battle Tactic Against Resistant Cancers

800x560-oct-5-2021

Technique Talk: Live-Cell Imaging Strategies to Quantify Phagocytosis

Microglia Tamp Down Neurogenesis

Inner Ear Undertakers

All Systems Go

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A person on an operation table getting anesthesia. A study revealed sex differences in ketamine anesthesia.

Female Brains Wake Up from Anesthesia Differently Than Male Brains

A woman in her 60s wears a yellow tank top and brown-rimmed glasses while placing a hormone-replacement patch on her upper arm.

Flawed Studies Linked Menopausal Hormone Therapy to Breast Cancer

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A hand holding $100 bills reaches out of a green-colored laptop screen, indicating a bribe.

Publisher Investigates an Alleged Peer Review Extortion Attempt

Multimedia

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Miltenyi
A model of a brain made of flat, multicolored pieces stacked together.

Mapping Tissues with Spatial Biology

August 2026 Digest cover
August 2026

Epic Fail: Sea-Monkeys Sabotage Fieldwork

When Barry Hicks set out to photograph thrombolites, thousands of unexpected visitors photobombed his underwater images.

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Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Advancing Respiratory Immunity Through Tissue-Resident Memory T Cell Research

Miltenyi
Overcoming Immunotherapy Resistance in Liver Cancer

Overcoming Immunotherapy Resistance in Liver Cancer

Axion Biosystems
Optimizing NGS Library Preparation for Reliable Sequencing Data

Optimizing NGS Library Preparation for Reliable Sequencing Data

Covaris
Using TCR Repertoire Sequencing to Advance Immunology Research

Using TCR Repertoire Sequencing to Advance Immunology Research

Miltenyi

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A photo of a scientist placing the Resipher device on a 96-well plate.

Resipher: Continuous Live-Cell Mitochondrial Respiration Monitoring in 96-Well Plates

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Conceptual image of ice and frost.

The VAULT100 PRO: Inside the most advanced Stirling Ultracold ULT freezer ever built.

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