An illustration depicting the mechanism of the Crunch cell targeting system developed by researchers at Kyoto University. A blue silhouette of a person stands on the left. On the right is a magnified image of inside the body, where purple malignant cells have yellow proteins on their surface. A green adaptor protein depicted as being attracted to the yellow proteins is flying to the cells, while an orange phagocyte is attached to the adaptor protein.

| 2 min read

An Engineered Protein Helps Phagocytes Gobble Up Diseased Cells

Researchers modified a protein in the cell elimination pathway to create a targeted system for destroying disease-causing cells, called Crunch.

3D conceptual image of purple-colored macrophages on a black background.

| 1 min read

Streamlining Macrophage Polarization Workflows

A 3D rendering of white macrophages engulfing blue bacteria.

| 3 min read

Microbes Fuel the Immune Cells That Engulf Them

phagocytosis

Microscopy image of a hair follicle shaft with clusters of orange debris surrounded by a group of green cells. Purple cells surround the hair root.

Stem Cells Dine on Dying Neighbors to Keep Tissues Fit

Danielle Gerhard, PhD | | 2 min read

Epithelial cells and fungal spores are marked with fluorescent dyes. Cells have an irregular shape and are shown in green and blue colors. Spores are spherical in shape and are labeled green if they are surrounded by p11 protein. A protein in mature phagosomes is labeled violet.

Fungal Spores Hijack a Host Protein to Escape Death

Mariella Bodemeier Loayza Careaga, PhD | | 3 min read

Illustration showing the path result of Eukaryogenesis

Infographic: Evolutionary Leaps Leading to Modern Eukaryotes

Amanda Heidt | | 2 min read

A microscope image of Legionellales bacteria infecting a protozoan

Ancestral Bacteria May Have Invaded Early Eukaryotic Cells

Clare Watson | | 3 min read

The adaptive and innate immune responses collaborate to attack T-cell resistant cancer cells

LabTalk Podcast - Phagocidal Macrophages: A New Battle Tactic Against Resistant Cancers

10x GenomicsandThe Scientist Creative Services Team | | 1 min read

800x560-oct-5-2021

Technique Talk: Live-Cell Imaging Strategies to Quantify Phagocytosis

Available on Demand

Microglia Tamp Down Neurogenesis

Kerry Grens | | 2 min read

Inner Ear Undertakers

Kerry Grens | | 2 min read

All Systems Go

Anna Azvolinsky | | 9 min read

Page 1 of 1 - 12 Total Items

Trending

A cross section of a pine stem shows cells stained purple and blue.

The Biggest Breakthroughs in Cell Biology in 2025

From microglia reprogramming to immune cell-based diagnostics, 2025 was a big year for breakthroughs in cell biology.

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

A brown dog stares at a spoon of peanut butter in front of its face with wide eyes.

Why Do Dogs Love Peanut Butter?

The reason dogs beg, sit, stay, and shake for peanut butter could be both evolutionarily wired and learned behavior.

Gollum, the extremely territorial character from The Lord of the Rings, famous for his line, “My precious,” sits on a rock, looking up.

The Gollum Effect: 44 Percent of Scientists Report Territorial Research Experiences

Survey data showed that hoarding research topics and resources, termed the Gollum effect, has a lasting impact on trainees and perpetuates a toxic research culture.

Multimedia

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.

December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

View this Issue

Research Resources

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Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Human iPSC-derived Models for Brain Disease Research

Human iPSC-derived Models for Neurodegenerative Disease Research

In this webinar, Jesús Tintos-Hernandez, Setsu Endoh-Yamagami, and Amaris Castañon will discuss the latest advances and innovations in neuroscience disease cell models.

Abstract wireframe sphere with colorful dots and connecting lines representing the complex cellular and molecular interactions within the tumor microenvironment.

Exploring the Inflammatory Tumor Microenvironment

Within the tumor microenvironment, networks of cells and molecular signals form a dynamic landscape that drives disease progression.

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BRANDTECH® Scientific Announces Strategic Partnership with Copia Scientific to Strengthen Sales and Service of the BRAND® Liquid Handling Station (LHS)

This partnership will enable both companies to reach a broader range of customers, including those with more complex and specialized workflows

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Enter Our 2026 Top Innovations Contest

Submit a cutting-edge product or technology for the chance to be recognized as one of The Scientist’s 2026 Top Innovations.

Biotium Expands Tyramide Signal Amplification Portfolio with Brighter and More Stable Dyes for Enhanced Spatial Imaging

Biotium's new TyraMax™ Amplification Dyes and Kits are available with the widest selection of colors for spatial analysis

LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

Ten-year Agreement to Provide a Secure, AI-enabled Forensic Laboratory Information Management System Supporting DHS Forensic, Scientific, and Testing Services