My lab has developed a protocol to easily assess the specificity of antibodies—and hopefully stem some of the reproducibility crisis.

The original experiment found brain activity as measured by fMRI was tied to particular genetic variants.

The new work calls into question the idea that neurons can be genetically engineered to fire in response to magnetic fields, a setback for the budding technique.

Its articles will include negative results, reproducibility studies, and peer reviewers’ names.

Many preclinical studies carried out in vivo are poorly designed and generate irreproducible data, but efforts to address the problem are on the rise.

Five independent groups got different results in a drug-response experiment, despite sharing protocols, reagents, and cell lines. The researchers identify technical variables that could be to blame.

Take a break from the bench to puzzle and peruse.

Scientists find varied microbiota among the same strain of mice from four vendors—and that variability affects their susceptibility to infection.

This could account for some reproducibility problems in cell line research, according to the authors of a comprehensive analysis of HeLa variants.