Study Challenges CRISPR Method for Making Conditional Knockout Mice
Study Challenges CRISPR Method for Making Conditional Knockout Mice
Researchers from 17 labs report low efficacy rates for the popular technique.
Study Challenges CRISPR Method for Making Conditional Knockout Mice
Study Challenges CRISPR Method for Making Conditional Knockout Mice

Researchers from 17 labs report low efficacy rates for the popular technique.

Researchers from 17 labs report low efficacy rates for the popular technique.

reproducibility
<em>PNAS</em> to Stop Publishing Its Print Edition in 2019
PNAS to Stop Publishing Its Print Edition in 2019
Kerry Grens | Sep 7, 2018
The move to online-only will allow for articles to be longer in length.
Latest Effort to Replicate Psych Studies Yields 62 Percent Success
Latest Effort to Replicate Psych Studies Yields 62 Percent Success
Kerry Grens | Aug 27, 2018
Among the experiments that came to the same result as the original, the effect size was smaller on average.
Studies Unable to Reproduce Results of Two Diabetes Papers
Studies Unable to Reproduce Results of Two Diabetes Papers
Anna Azvolinsky | Aug 10, 2018
The original work found that an anti-malaria drug or the neurotransmitter GABA could increase the number of insulin-producing pancreatic cells in mice.
Effort to Reproduce Cancer Studies Scales Down to 18 Papers
Effort to Reproduce Cancer Studies Scales Down to 18 Papers
Diana Kwon | Aug 1, 2018
The Reproducibility Project: Cancer Biology initially aimed to replicate the results of 50 high-impact research articles.
Replication Failures Highlight Biases in Ecology and Evolution Science
Replication Failures Highlight Biases in Ecology and Evolution Science
Yao-Hua Law | Aug 1, 2018
As robust efforts fail to reproduce findings of influential zebra finch studies from the 1980s, scientists discuss ways to reduce bias in such research.
Horizontal Gene Transfer in Bdelloid Rotifers Questioned
Horizontal Gene Transfer in Bdelloid Rotifers Questioned
Abby Olena | Jul 12, 2018
A re-analysis of sequencing data from a 2016 study of these tiny metazoans reveals possible contamination, rather than an exchange of DNA among species.
Roland Nardone, Advocate for Cell-Line Authentication, Dies
Roland Nardone, Advocate for Cell-Line Authentication, Dies
Kerry Grens | Jul 11, 2018
The Catholic University of America professor was also known for his summer workshops on the latest techniques.
Bringing the Internet of Things into the Lab
Bringing the Internet of Things into the Lab
Abby Olena | Jun 1, 2018
The IoT can link up many facets of research—from laboratory equipment to ideas—but scientists must be ready for the questions its implementation could raise.
Scientists Reverse Their Controversial Findings of CRISPR's Off-Target Effects
Scientists Reverse Their Controversial Findings of CRISPR's Off-Target Effects
Diana Kwon | Mar 28, 2018
Last year, researchers claimed the gene-editing method had accuracy issues, but a new whole-genome sequencing analysis by the same team finds otherwise.