Opinion: Scientists Need to Demand Better Antibody Validation
Opinion: Scientists Need to Demand Better Antibody Validation
My lab has developed a protocol to easily assess the specificity of antibodies—and hopefully stem some of the reproducibility crisis.
Opinion: Scientists Need to Demand Better Antibody Validation
Opinion: Scientists Need to Demand Better Antibody Validation

My lab has developed a protocol to easily assess the specificity of antibodies—and hopefully stem some of the reproducibility crisis.

My lab has developed a protocol to easily assess the specificity of antibodies—and hopefully stem some of the reproducibility crisis.

reproducibility
Replication Refutes Study Linking Neuroimaging to Genetics
Replication Refutes Study Linking Neuroimaging to Genetics
Emma Yasinski | Sep 30, 2019
The original experiment found brain activity as measured by fMRI was tied to particular genetic variants.
Two Studies Fail to Replicate Magnetogenetics Research
Two Studies Fail to Replicate Magnetogenetics Research
Katarina Zimmer | Sep 20, 2019
The new work calls into question the idea that neurons can be genetically engineered to fire in response to magnetic fields, a setback for the budding technique.
New Journal Seeks Typically Overlooked Studies
New Journal Seeks Typically Overlooked Studies
Emily Makowski | Sep 18, 2019
Its articles will include negative results, reproducibility studies, and peer reviewers’ names.
Fixing the Flaws in Animal Research
Fixing the Flaws in Animal Research
Diana Kwon | Sep 1, 2019
Many preclinical studies carried out in vivo are poorly designed and generate irreproducible data, but efforts to address the problem are on the rise.
Potential Causes of Irreproducibility Revealed
Potential Causes of Irreproducibility Revealed
Abby Olena | Jul 11, 2019
Five independent groups got different results in a drug-response experiment, despite sharing protocols, reagents, and cell lines. The researchers identify technical variables that could be to blame.
Ten Minute Sabbatical
Ten Minute Sabbatical
The Scientist Staff | Jun 1, 2019
Take a break from the bench to puzzle and peruse.
Microbes May Take Some of the Blame for the Reproducibility Crisis
Microbes May Take Some of the Blame for the Reproducibility Crisis
Emma Yasinski | Apr 5, 2019
Scientists find varied microbiota among the same strain of mice from four vendors—and that variability affects their susceptibility to infection.
HeLa Cells from Different Labs Vary in Genetics, Phenotype
HeLa Cells from Different Labs Vary in Genetics, Phenotype
Katarina Zimmer | Feb 26, 2019
This could account for some reproducibility problems in cell line research, according to the authors of a comprehensive analysis of HeLa variants.
The Open Data Explosion
The Open Data Explosion
Viviane Callier | Jan 1, 2019
Scientists are working to maximize the benefits and minimize the costs of sharing.