First RNAi Therapy Approved by FDA
First RNAi Therapy Approved by FDA
Alnylam’s patisiran interferes with the production of a mutated protein present in people with hereditary transthyretin amyloidosis.
First RNAi Therapy Approved by FDA
First RNAi Therapy Approved by FDA

Alnylam’s patisiran interferes with the production of a mutated protein present in people with hereditary transthyretin amyloidosis.

Alnylam’s patisiran interferes with the production of a mutated protein present in people with hereditary transthyretin amyloidosis.

RNAi
RNA Interference Drug Excels in Clinical Trials to Treat Rare Disorder
RNA Interference Drug Excels in Clinical Trials to Treat Rare Disorder
Katarina Zimmer | Nov 3, 2017
If approved, patisiran will be the first RNAi therapeutic on the market. 
CRISPR System Targets RNA in Mammalian Cells
CRISPR System Targets RNA in Mammalian Cells
Anna Azvolinsky | Oct 4, 2017
Researchers engineer bacterial CRISPR-Cas13 to knock down RNA in mammalian cells.
Massive RNAi Screens Probe for Genes Important to Cancer
Massive RNAi Screens Probe for Genes Important to Cancer
Kerry Grens | Jul 27, 2017
Two freely available databases include data on hundreds of human cancer cell lines. 
Mammalian Immunity: What’s RNAi Got to Do with It?
Mammalian Immunity: What’s RNAi Got to Do with It?
Shawna Williams | Jul 21, 2017
A new study adds to the evidence that mammalian cells can use small interfering RNAs to defend against viruses, but questions remain about physiological importance.
First RNAi Insecticide Approved
First RNAi Insecticide Approved
Aggie Mika | Jun 27, 2017
This month, the EPA registered four products that include RNA interference technology intended to control corn rootworms. 
The RNA Age: A Primer
The RNA Age: A Primer
Ruth Williams | May 11, 2017
Our guide to all known forms of RNA, from cis-NAT to vault RNA and everything in between.
RNAi’s Future in Drug-Target Screening
RNAi’s Future in Drug-Target Screening
Catherine Offord | Apr 17, 2017
A recent CRISPR study contradicted years of RNA interference research on a well-studied cancer drug target. But is it the last nail in the coffin for RNAi as a screening tool? 
RNA Interference Between Kingdoms
RNA Interference Between Kingdoms
Kerry Grens | Feb 1, 2017
Plants and fungi can use conserved RNA interference machinery to regulate each other’s gene expression—and scientists think they can make use of this phenomenon to create a new generation of pesticides.
Oligonucleotide Therapeutics Near Approval
Oligonucleotide Therapeutics Near Approval
Catherine Offord | Dec 1, 2016
Successful late-stage clinical trials could mark the maturation of a new drug development platform, but the path to commercialization is not without hurdles.