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CRISPR System Targets RNA in Mammalian Cells
Anna Azvolinsky | Oct 4, 2017
Researchers engineer bacterial CRISPR-Cas13 to knock down RNA in mammalian cells.
Massive RNAi Screens Probe for Genes Important to Cancer
Kerry Grens | Jul 27, 2017
Two freely available databases include data on hundreds of human cancer cell lines.
Mammalian Immunity: What’s RNAi Got to Do with It?
Shawna Williams | Jul 21, 2017
A new study adds to the evidence that mammalian cells can use small interfering RNAs to defend against viruses, but questions remain about physiological importance.
First RNAi Insecticide Approved
Aggie Mika | Jun 27, 2017
This month, the EPA registered four products that include RNA interference technology intended to control corn rootworms.
The RNA Age: A Primer
Ruth Williams | May 11, 2017
Our guide to all known forms of RNA, from cis-NAT to vault RNA and everything in between.
RNAi’s Future in Drug-Target Screening
Catherine Offord | Apr 17, 2017
A recent CRISPR study contradicted years of RNA interference research on a well-studied cancer drug target. But is it the last nail in the coffin for RNAi as a screening tool?
RNA Interference Between Kingdoms
Kerry Grens | Feb 1, 2017
Plants and fungi can use conserved RNA interference machinery to regulate each other’s gene expression—and scientists think they can make use of this phenomenon to create a new generation of pesticides.
Oligonucleotide Therapeutics Near Approval
Catherine Offord | Dec 1, 2016
Successful late-stage clinical trials could mark the maturation of a new drug development platform, but the path to commercialization is not without hurdles.
Gut Bacteria Vectors
Ruth Williams | Jun 1, 2016
Researchers mix bacteria genetically engineered to express double-stranded RNA into insect food.
Life Span Factors
Catherine Offord | Jun 1, 2016
A recent paper challenges earlier findings that germline factors expressed in normal body cells influence life span in