RNAi
FDA OKs siRNA Ebola Drug
FDA OKs siRNA Ebola Drug
Kerry Grens | Sep 23, 2014
The US Food and Drug Administration gives the green light to deploy an experimental short interfering RNA treatment against Ebola.
Head Scratchers
Head Scratchers
Mary Beth Aberlin | Sep 1, 2014
Many natural phenomena elude our understanding.
The Second Coming of RNAi
The Second Coming of RNAi
Eric Bender | Sep 1, 2014
Now showing clinical progress against liver diseases, the gene-silencing technique begins to fulfill some of its promises.
Roche Set to Buy RNAi Firm
Roche Set to Buy RNAi Firm
Bob Grant | Aug 6, 2014
The Swiss pharmaceutical giant will reportedly pay $450 million for a Danish biotech company that develops drugs that silence microRNAs.
Unraveling the Female Fruit Fly Mating Circuit
Unraveling the Female Fruit Fly Mating Circuit
Kate Yandell | Jul 2, 2014
Three teams identify different components of the female Drosophila nervous system that govern mating behaviors.
Exploring the Roles of Enhancer RNAs
Exploring the Roles of Enhancer RNAs
Ashley P. Taylor | May 7, 2014
Scientists have recently discovered that enhancers are often transcribed into RNAs. But they’re still not sure what, if anything, these eRNAs do.
Fighting Viruses with RNAi
Fighting Viruses with RNAi
Ruth Williams | Oct 10, 2013
The long-debated issue of whether mammals can use RNA interference as an antiviral defense mechanism is finally put to rest.
RNAi Remedy Lowers Cholesterol
RNAi Remedy Lowers Cholesterol
Abby Olena | Oct 3, 2013
A Phase 1 clinical trial demonstrates the safety and efficacy of an siRNA-based, cholesterol-lowering drug.
Shushing RNA
Shushing RNA
Edyta Zielinska | Aug 1, 2013
The cell detains potentially harmful RNA messages in the spliceosome long enough to create interfering RNAs against the aberrant messages.
Gene Silencing Is Golden
Gene Silencing Is Golden
Carina Storrs | Aug 1, 2013
A beginner’s how-to on RNAi screening in mammalian cells