Spleen-to-Liver Signals Control Systemic Inflammation
Spleen-to-Liver Signals Control Systemic Inflammation
In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger.
Spleen-to-Liver Signals Control Systemic Inflammation
Spleen-to-Liver Signals Control Systemic Inflammation

In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger.

In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger.

sepsis
Janelle Ayres Explores the Ways in Which Animals Tolerate Disease
Janelle Ayres Explores the Ways in Which Animals Tolerate Disease
Amy Schleunes | Jun 1, 2020
The Salk Institute researcher was one of the first to show that killing a pathogen isn’t the only way to survive an infection.
Seeding the Gut Microbiome Prevents Sepsis in Infants
Seeding the Gut Microbiome Prevents Sepsis in Infants
Anna Azvolinsky | Aug 16, 2017
An oral mix of a pre- and probiotic can decrease deaths from the condition, according to the results of a large clinical trial conducted in rural India. 
T Cells That Drive Toxic Shock in Mice Identified
T Cells That Drive Toxic Shock in Mice Identified
Ashley Yeager | Jun 20, 2017
Overzealous activity by mucosa-associated invariant T (MAIT) cells in response to bacterial toxins can lead to illness instead of stopping it.
A Blood Test To Determine When Antibiotics Are Warranted
A Blood Test To Determine When Antibiotics Are Warranted
Alison F. Takemura | Jul 7, 2016
Scientists can assay gene activity to distinguish between bacterial and viral infections.
Diagnosing Sepsis
Diagnosing Sepsis
Jef Akst | May 14, 2015
An 11-gene set may help identify sepsis early, before it’s too late.
Next Generation: Blood-Cleansing Device
Next Generation: Blood-Cleansing Device
Anna Azvolinsky | Sep 14, 2014
An external device that mimics the structure of a spleen can cleanse the blood of rats with acute sepsis, ridding the fluid of pathogens and toxins.
More Questions About IV Drug
More Questions About IV Drug
Bob Grant | Oct 17, 2012
Another clinical trial raises concerns about the efficacy and safety of a common intravenous treatment for patients that have lost large amounts of blood.
FDA to Debate Starch Treatment
Bob Grant | Aug 31, 2012
The US Food and Drug Administration will consider whether or not to stop the use of intravenous starch solutions to replace lost blood.
Kerfuffle Over Antishock Drug Paper
Bob Grant | Aug 3, 2012
A slight flaw in a study on the effectiveness of a drug widely used to combat shock in critically injured patients almost gets a Danish researcher sued for millions.