sepsis

CDC investigators continue to search for the source of the bacteria that caused four infections—two of them lethal—in four different states. The Scientist spoke with melioidosis expert Bart Currie about the disease.

In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger.

The Salk Institute researcher was one of the first to show that killing a pathogen isn’t the only way to survive an infection.

An oral mix of a pre- and probiotic can decrease deaths from the condition, according to the results of a large clinical trial conducted in rural India. 

Overzealous activity by mucosa-associated invariant T (MAIT) cells in response to bacterial toxins can lead to illness instead of stopping it.

Scientists can assay gene activity to distinguish between bacterial and viral infections.

An 11-gene set may help identify sepsis early, before it’s too late.

An external device that mimics the structure of a spleen can cleanse the blood of rats with acute sepsis, ridding the fluid of pathogens and toxins.

Another clinical trial raises concerns about the efficacy and safety of a common intravenous treatment for patients that have lost large amounts of blood.

The US Food and Drug Administration will consider whether or not to stop the use of intravenous starch solutions to replace lost blood.

A slight flaw in a study on the effectiveness of a drug widely used to combat shock in critically injured patients almost gets a Danish researcher sued for millions.

A new study suggests that a drug for blood poisoning that was withdrawn by its manufacturer does work after all.