News & Opinion
Top 10 Innovations
Cell & Molecular Biology
Disease & Medicine
Ecology & Environment
Genetics & Genomics
Pharma & Biotech
Image of the Day
Paused RNA Polymerase Quashes New Initiation of Transcription
Shawna Williams | Oct 1, 2017
Pauses may help cells fine-tune gene expression.
The Role of DNA Base Modifications
Skirmantas Kriaucionis | Sep 1, 2017
Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.
Infographic: The Various Forms of Methylated DNA
Skirmantas Kriaucionis | Aug 31, 2017
To expand the basic nucleotide alphabet, many species modify their DNA with epigenetic marks.
Nuclear Pores Come into Sharper Focus
André Hoelz, Daniel H. Lin | Dec 1, 2016
Solving a long-standing structural puzzle will open the door to understanding one of the cell’s most enigmatic machines.
With CRISPR, Scientists Make Neurons From Fibroblasts
Kerry Grens | Aug 15, 2016
Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.
Exercise Boosts Telomere Transcription
Anna Azvolinsky | Jul 27, 2016
Endurance exercise and metabolism are linked to transcriptional activation of human telomeres, researchers propose.
Another Role for ApoE?
Ashley P. Taylor | Jan 20, 2016
Key Alzheimer’s disease–related protein may be a transcriptional regulator.
Fearless about Folding
Anna Azvolinsky | Jan 1, 2016
Susan Lindquist has never shied away from letting her curiosity guide her research career.
Shingo Kajimura: Fishing for Answers
Karen Zusi | Nov 1, 2015
Assistant Professor, Department of Cell and Tissue Biology, University of California, San Francisco. Age: 39
CRISPR–Enabled Epigenome Editing
Kerry Grens | Apr 6, 2015
Researchers apply the genome-editing technology to alter histones at distant gene enhancers, controlling gene expression.