When the nucleic acid spirals to the left, it takes on a zig-zag shape known as Z-DNA that appears to regulate RNA editing.

A gene responsible for the free-moving, primitive nature of fetal cells is expressed in some breast cancer cells in mice and humans.

Pauses may help cells fine-tune gene expression.

Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.

To expand the basic nucleotide alphabet, many species modify their DNA with epigenetic marks.

Solving a long-standing structural puzzle will open the door to understanding one of the cell’s most enigmatic machines.

Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.

Endurance exercise and metabolism are linked to transcriptional activation of human telomeres, researchers propose.

Key Alzheimer’s disease–related protein may be a transcriptional regulator.