A Single Transcription Factor Changes Ants to Queens

The transcription factor can also drive the opposite transition depending on which hormone activates it, according to a new study.

Written byAbby Olena, PhD
| 3 min read
A black and brown ant stands over various sizes of whitish purple, oval shaped larvae and yellow, oblong eggs
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Indian jumping ants (Harpegnathos saltator) are unusual in that worker ants can, in the absence of a queen, make a switch to a queen-like status in order to reproduce and keep the colony going. In a study published November 4 in Cell, researchers found that the shift from worker to queen is facilitated by the response of transcription factor Krüppel homolog 1 (Kr-h1) to hormones that are present at different levels in queen and worker ants.

“As a field, we’re very interested in understanding the evolution of sociality,” says Tali Reiner Brodetzki, who studies social behavior in ants at Rutgers University–Camden in New Jersey and was not involved in the work. Most social insects can’t change their caste, she adds, but studying this plasticity could yield insights into how other types of plasticity work.

Previous work has shown that Indian jumping ants can change the size of their brains depending ...

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Meet the Author

  • abby olena

    As a freelancer for The Scientist, Abby reports on new developments in life science for the website. She has a PhD from Vanderbilt University and got her start in science journalism as the Chicago Tribune’s AAAS Mass Media Fellow in 2013. Following a stint as an intern for The Scientist, Abby was a postdoc in science communication at Duke University, where she developed and taught courses to help scientists share their research. In addition to her work as a science journalist, she leads science writing and communication workshops and co-produces a conversational podcast. She is based in Alabama.  

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