Eight Proteins Turn Mouse Stem Cells into Egglike Cells
Eight Proteins Turn Mouse Stem Cells into Egglike Cells
The identification of the transcription factors that elicit oocyte growth will aid reproductive biology research and might help women with fertility issues, scientists say.  
Eight Proteins Turn Mouse Stem Cells into Egglike Cells
Eight Proteins Turn Mouse Stem Cells into Egglike Cells

The identification of the transcription factors that elicit oocyte growth will aid reproductive biology research and might help women with fertility issues, scientists say.  

The identification of the transcription factors that elicit oocyte growth will aid reproductive biology research and might help women with fertility issues, scientists say.  

transcription factors
Genetic Reprogramming Restores Vision in Mice: Study
Genetic Reprogramming Restores Vision in Mice: Study
Max Kozlov | Dec 6, 2020
Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.
Image of the Day: Tomato Domestication
Image of the Day: Tomato Domestication
Amy Schleunes | Mar 30, 2020
Scientists identify a transcription factor that plays a key role in increased fruit size.
Oct4, Considered Vital for Creating iPSCs, Actually Isn’t Needed
Oct4, Considered Vital for Creating iPSCs, Actually Isn’t Needed
Emma Yasinski | Nov 8, 2019
Dropping the transcription factor from the four so-called Yamanaka factors reduces the efficiency of inducing the production of stem cells, but the resulting cells are of greater quality.
Caught on Camera
Caught on Camera
The Scientist Staff | Oct 1, 2018
Selected Images of the Day from the-scientist.com
Image of the Day: Switch Gears
Image of the Day: Switch Gears
Sukanya Charuchandra | Sep 10, 2018
A gene responsible for the free-moving, primitive nature of fetal cells is expressed in some breast cancer cells in mice and humans.
Image of the Day: Kaleidoscope
Image of the Day: Kaleidoscope
Sukanya Charuchandra | Aug 27, 2018
A single transcription factor regulates a harlequin ladybird’s colors.
Reprogrammed Müller Glia Restore Vision in Mice
Reprogrammed Müller Glia Restore Vision in Mice
Ashley Yeager | Aug 15, 2018
A double gene-transfer therapy transformed the non-neuronal cells into rod photoreceptors in the retinas of animal models of congenital blindness.
Image of the Day: Cooking Up Neurons
Image of the Day: Cooking Up Neurons
The Scientist Staff, The Scientist Staff | May 11, 2018
Using different combinations of transcription factors, researchers create a diverse array of neurons from mouse skin cells.
Colorblindness Study Reveals Unexpected Way to Make Blood Vessels
Colorblindness Study Reveals Unexpected Way to Make Blood Vessels
Ashley Yeager | May 1, 2018
Researchers stumbled across the connection while searching for ways to reduce vision problems in people with achromatopsia.
Image of the Day: Gene Expression
Image of the Day: Gene Expression
The Scientist Staff, The Scientist Staff | Apr 9, 2018
A new algorithm scrutinizes the most hard-to-read segments of the genome.
Paused RNA Polymerase Quashes New Initiation of Transcription
Paused RNA Polymerase Quashes New Initiation of Transcription
Shawna Williams | Oct 1, 2017
Pauses may help cells fine-tune gene expression.
Bacterial Protein Acts as Prion in Yeast and <em>E. coli</em>
Bacterial Protein Acts as Prion in Yeast and E. coli
Jef Akst | Jan 16, 2017
Clostridium botulinum produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in E. coli, according to a study.
Synthetic Sensors
Synthetic Sensors
Ruth Williams | Dec 1, 2016
Engineered circuits detect endogenous transcription factors to drive cellular outputs.
Infographic: How to Build a Synthetic Sensor
Infographic: How to Build a Synthetic Sensor
Ruth Williams | Nov 30, 2016
Scientists designed a genetic sensor-and-readout system, based on detecting a transcription factor, that performs a custom cellular activity.
How These Rodents Got Their Stripes
How These Rodents Got Their Stripes
Ashley P. Taylor | Nov 2, 2016
The African striped mouse and the chipmunk develop dorsal stripes through a newly identified mechanism of coat color variation.
With CRISPR, Scientists Make Neurons From Fibroblasts
With CRISPR, Scientists Make Neurons From Fibroblasts
Kerry Grens | Aug 15, 2016
Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.
Pradeep Chaluvally-Raghavan: Curious about Cancer
Pradeep Chaluvally-Raghavan: Curious about Cancer
Jef Akst | Apr 1, 2016
Instructor, Department of Systems Biology, University of Texas MD Anderson Cancer Center. Age: 38
Adding Padding
Adding Padding
Karen Zusi | Nov 1, 2015
Adipogenesis in mice has alternating genetic requirements throughout the animals’ lives.
Two Papers Pulled for Figure Fraud
Two Papers Pulled for Figure Fraud
Kerry Grens | Aug 17, 2015
A University of Florida investigation has found the lead author on both studies faked data on stress response in Caenorhabditis elegans.