Oct4, Considered Vital for Creating iPSCs, Actually Isn’t Needed
Oct4, Considered Vital for Creating iPSCs, Actually Isn’t Needed
Dropping the transcription factor from the four so-called Yamanaka factors reduces the efficiency of inducing the production of stem cells, but the resulting cells are of greater quality.
Oct4, Considered Vital for Creating iPSCs, Actually Isn’t Needed
Oct4, Considered Vital for Creating iPSCs, Actually Isn’t Needed

Dropping the transcription factor from the four so-called Yamanaka factors reduces the efficiency of inducing the production of stem cells, but the resulting cells are of greater quality.

Dropping the transcription factor from the four so-called Yamanaka factors reduces the efficiency of inducing the production of stem cells, but the resulting cells are of greater quality.

transcription factors
Caught on CameraCaught on Camera
Caught on Camera
The Scientist Staff | Oct 1, 2018
Selected Images of the Day from the-scientist.com
Image of the Day: Switch Gears
Image of the Day: Switch Gears
Sukanya Charuchandra | Sep 10, 2018
A gene responsible for the free-moving, primitive nature of fetal cells is expressed in some breast cancer cells in mice and humans.
Image of the Day: Kaleidoscope
Image of the Day: Kaleidoscope
Sukanya Charuchandra | Aug 27, 2018
A single transcription factor regulates a harlequin ladybird’s colors.
Reprogrammed Müller Glia Restore Vision in Mice
Reprogrammed Müller Glia Restore Vision in Mice
Ashley Yeager | Aug 15, 2018
A double gene-transfer therapy transformed the non-neuronal cells into rod photoreceptors in the retinas of animal models of congenital blindness.
Image of the Day: Cooking Up Neurons
Image of the Day: Cooking Up Neurons
The Scientist Staff, The Scientist Staff | May 11, 2018
Using different combinations of transcription factors, researchers create a diverse array of neurons from mouse skin cells.
Colorblindness Study Reveals Unexpected Way to Make Blood Vessels
Colorblindness Study Reveals Unexpected Way to Make Blood Vessels
Ashley Yeager | May 1, 2018
Researchers stumbled across the connection while searching for ways to reduce vision problems in people with achromatopsia.
Image of the Day: Gene Expression
Image of the Day: Gene Expression
The Scientist Staff, The Scientist Staff | Apr 9, 2018
A new algorithm scrutinizes the most hard-to-read segments of the genome.
Paused RNA Polymerase Quashes New Initiation of Transcription
Paused RNA Polymerase Quashes New Initiation of Transcription
Shawna Williams | Oct 1, 2017
Pauses may help cells fine-tune gene expression.
Bacterial Protein Acts as Prion in Yeast and <em>E. coli</em>
Bacterial Protein Acts as Prion in Yeast and E. coli
Jef Akst | Jan 17, 2017
Clostridium botulinum produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in E. coli, according to a study.