Researchers repaired what is otherwise irreversible damage in the animals’ ocular neurons, by activating transcription factors ordinarily used to generate induced pluripotent stem cells.

Scientists identify a transcription factor that plays a key role in increased fruit size.

Dropping the transcription factor from the four so-called Yamanaka factors reduces the efficiency of inducing the production of stem cells, but the resulting cells are of greater quality.

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A gene responsible for the free-moving, primitive nature of fetal cells is expressed in some breast cancer cells in mice and humans.

A single transcription factor regulates a harlequin ladybird’s colors.

A double gene-transfer therapy transformed the non-neuronal cells into rod photoreceptors in the retinas of animal models of congenital blindness.

Using different combinations of transcription factors, researchers create a diverse array of neurons from mouse skin cells.

Researchers stumbled across the connection while searching for ways to reduce vision problems in people with achromatopsia.

A new algorithm scrutinizes the most hard-to-read segments of the genome.

Pauses may help cells fine-tune gene expression.

Clostridium botulinum produces a transcription factor that can aggregate and self-propagate a prion-like form, leading to genome-wide changes in gene expression in E. coli, according to a study.

Engineered circuits detect endogenous transcription factors to drive cellular outputs.

Scientists designed a genetic sensor-and-readout system, based on detecting a transcription factor, that performs a custom cellular activity.

The African striped mouse and the chipmunk develop dorsal stripes through a newly identified mechanism of coat color variation.

Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.

Instructor, Department of Systems Biology, University of Texas MD Anderson Cancer Center. Age: 38

Adipogenesis in mice has alternating genetic requirements throughout the animals’ lives.

A University of Florida investigation has found the lead author on both studies faked data on stress response in Caenorhabditis elegans.