transcription factors
How These Rodents Got Their Stripes
How These Rodents Got Their Stripes
Ashley P. Taylor | Nov 2, 2016
The African striped mouse and the chipmunk develop dorsal stripes through a newly identified mechanism of coat color variation.
With CRISPR, Scientists Make Neurons From Fibroblasts
With CRISPR, Scientists Make Neurons From Fibroblasts
Kerry Grens | Aug 15, 2016
Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.
Pradeep Chaluvally-Raghavan: Curious about Cancer
Pradeep Chaluvally-Raghavan: Curious about Cancer
Jef Akst | Apr 1, 2016
Instructor, Department of Systems Biology, University of Texas MD Anderson Cancer Center. Age: 38
Adding Padding
Adding Padding
Karen Zusi | Nov 1, 2015
Adipogenesis in mice has alternating genetic requirements throughout the animals’ lives.
Two Papers Pulled for Figure Fraud
Two Papers Pulled for Figure Fraud
Kerry Grens | Aug 17, 2015
A University of Florida investigation has found the lead author on both studies faked data on stress response in Caenorhabditis elegans.
Toggling Between Life and Death
Toggling Between Life and Death
Ashley P. Taylor | Apr 1, 2015
In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.
Benefits of Missing MYC
Benefits of Missing MYC
Kate Yandell | Jan 22, 2015
Mice engineered to have just one copy of the gene Myc live longer, healthier lives than wild-type animals.
Toward Lab-Grown Gametes
Toward Lab-Grown Gametes
Tracy Vence | Dec 30, 2014
From stem cells, scientists generate early egg- and sperm-like cells in vitro.
Similarities and Differences
Similarities and Differences
Molly Sharlach | Nov 21, 2014
Results from the Mouse ENCODE project point to key divergences in gene regulation architecture compared to humans.
How a Memory Is Made
How a Memory Is Made
Molly Sharlach | Nov 13, 2014
Transcription factor levels dictate which neurons in a network store a memory.