News & Opinion
Top 10 Innovations
Cell & Molecular Biology
Disease & Medicine
Ecology & Environment
Genetics & Genomics
Pharma & Biotech
Image of the Day
Infographic: How to Build a Synthetic Sensor
Ruth Williams | Nov 30, 2016
Scientists designed a genetic sensor-and-readout system, based on detecting a transcription factor, that performs a custom cellular activity.
How These Rodents Got Their Stripes
Ashley P. Taylor | Nov 2, 2016
The African striped mouse and the chipmunk develop dorsal stripes through a newly identified mechanism of coat color variation.
With CRISPR, Scientists Make Neurons From Fibroblasts
Kerry Grens | Aug 15, 2016
Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.
Pradeep Chaluvally-Raghavan: Curious about Cancer
Jef Akst | Apr 1, 2016
Instructor, Department of Systems Biology, University of Texas MD Anderson Cancer Center. Age: 38
Karen Zusi | Nov 1, 2015
Adipogenesis in mice has alternating genetic requirements throughout the animals’ lives.
Two Papers Pulled for Figure Fraud
Kerry Grens | Aug 17, 2015
A University of Florida investigation has found the lead author on both studies faked data on stress response in
Toggling Between Life and Death
Ashley P. Taylor | Apr 1, 2015
In estrogen receptor–positive breast cancer, the transcription factor IRF1 tips the balance between cellular suicide and survival through autophagy.
Benefits of Missing MYC
Kate Yandell | Jan 22, 2015
Mice engineered to have just one copy of the gene
live longer, healthier lives than wild-type animals.
Toward Lab-Grown Gametes
Tracy Vence | Dec 30, 2014
From stem cells, scientists generate early egg- and sperm-like cells in vitro.
Similarities and Differences
Molly Sharlach | Nov 21, 2014
Results from the Mouse ENCODE project point to key divergences in gene regulation architecture compared to humans.