transcriptome

The extent to which transcription is higher in tumor cells than in surrounding nontumor cells is associated with bad prognoses in several cancer types.

Follow the roadmap to successful single cell transcriptomic workflows and outputs.

An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.

A new study using fairly complete genetic datasets of two phyla of small suspension feeders (Ectoprocta and Entoprocta) reopens the debate on the phylogenetic relationships between them and other animals.

The molecular biologist studies how chemical modifications to RNA building blocks change the way RNA regulates complex cellular processes.

Six key questions help researchers determine the right approach for a given gene expression study.

Differences in the expression of genes associated with antiviral immunity and lung inflammation may contribute to a more serious COVID-19 infection.

The presence of a particular set of RNAs in the blood forewarns of an onset of severe symptoms and points to the cells involved.

A single-cell map of C. elegans’s transcriptome during development finds cell lineages that start out genetically different and end up as cells of similar function and genetic profile.

Suppressing the natural age-related increase in neuronal excitation lengthens the lives of worms, and there are indications that the same may be true for mice and humans.

Researchers track which genes are active in the polyp during successive cell states.

Transcriptional profiling of post-mortem human brains reveals commonalities in the genes over- and under-expressed in schizophrenia, bipolar disorder, autism, and major depression.