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Cuboidal DNA origami block containing parallel double helices (gray columns) decorated with tumor antigens (green proteins) and CpG adjuvants (yellow helices) on opposing faces.
Fighting Tumors with DNA Origami
Researchers bolster antitumor immune defenses using cancer vaccines made from DNA origami.
Fighting Tumors with DNA Origami
Fighting Tumors with DNA Origami

Researchers bolster antitumor immune defenses using cancer vaccines made from DNA origami.

Researchers bolster antitumor immune defenses using cancer vaccines made from DNA origami.

tumor

TK
Infographic: Vaccinating Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 1 min read
Cancer vaccines offer the opportunity to use the patient’s own immune system in the fight against tumors.
A needle drawing up fluid from an unlabeled vial.
Cancer Vaccination as a Promising New Treatment Against Tumors
Shelby Bradford, PhD | Mar 15, 2024 | 10+ min read
Vaccination has beaten back infections for more than a century. Now, it may be the next big step in battling cancer.
Exploring the Tumor Microenvironment with Spatial Biology
Exploring the Tumor Microenvironment with Spatial Biology
The Scientist Staff | 1 min read
In this webinar, Pinaki Bose and Fei Chen will discuss how scientists use spatial biology techniques to study the tumor microenvironment.
A scientist not in frame is holding a plant leave with forceps in one hand and a petri dish with more leaves in the other.
Mean, Green, Antibody-producing Machines
Shelby Bradford, PhD | Dec 1, 2023 | 2 min read
A plant-based monoclonal antibody goes head-to-head with its commercial counterpart to target tumors in mice.
Tasmanian devil wrapped in blanket
Tasmanian Devils Face Threats from Rapidly Evolving Facial Cancers 
Natalia Mesa, PhD | Jun 30, 2023 | 3 min read
A genetic study tracked the evolution of two transmissible cancers currently ravaging populations of Tasmanian devils.
New Strategies for Cancer Immunotherapy
New Strategies for Cancer Immunotherapy
The Scientist | 2 min read
An expert panel will discuss the interplay between cancer and the immune system, and how researchers develop immunotherapies and other immune-supporting strategies against cancer. 
Histological image of ccRCC
Mutational Signature Indicates Risk of Kidney Cancer Recurrence
Holly Barker, PhD | Mar 1, 2023 | 2 min read
DNA sequencing can identify mutations that predict recurrence of renal cell carcinoma and may help low-risk patients avoid unnecessary treatment, a study finds.
Red T cell
Jumping Genes Put a Target on Cancerous Cells
Natalia Mesa, PhD | Feb 14, 2023 | 4 min read
Two studies find that tumor-specific antigens are often peptides that result from a splicing event between exons and transposable elements.
summit
How Can Core Labs Help You Get Started with NGS?
The Scientist | 1 min read
Next-generation sequencing (NGS) core facility scientists and researchers new to NGS discuss their fruitful collaborations, highlighting how to receive expert help from genomics facilities.
A colorful image of a tumor
Opinion: Stopping the Cancer Cells that Thrive on Chemotherapy
Chengsheng Wu, David Cheresh, and Sara Weis; The Conversation | Jan 17, 2023 | 5 min read
Research into how pancreatic tumors adapt to stress could lead to a new treatment approach.
A black-and-white photo of a person’s hands holding a black-and-white barred chicken. The feathers of its breast have been pulled back to reveal a large tumor.
Transmissible Tumors, 1909
Katherine Irving | Jan 2, 2023 | 2 min read
Pathologist Peyton Rous made a groundbreaking discovery in the early 20th century, but his work wasn’t widely recognized until more than 40 years later. 
Test tubes containing liquid biopsy samples with circulating tumor DNA (ctDNA)
Supporting the Evolution of Liquid Biopsies
The Scientist Creative Services Team in collaboration with Twist Bioscience | 1 min read
Sequencing circulating tumor DNA (ctDNA) within liquid biopsies permits tumor identification and tracking. 
An artist’s rendition of transcription inside a nucleus
Hypertranscription by Tumors Is Linked to Poorer Cancer Outcomes: Study
Sophie Fessl, PhD | Dec 13, 2022 | 3 min read
The extent to which transcription is higher in tumor cells than in surrounding nontumor cells is associated with bad prognoses in several cancer types.
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
Overcoming T Cell Therapy Barriers with Engineered Proteins
Overcoming T Cell Therapy Barriers with Engineered Proteins
The Scientist | 1 min read
Shannon Oda will discuss how to develop novel engineered fusion proteins to improve T cell therapies against hematological and solid tumors.
Pink- and purple-stained cells clustered into glands
Phenotypic Variation in Cancer Cells Often Not Due to Mutations
Jef Akst | Oct 26, 2022 | 3 min read
Most differences in gene expression among cells within a tumor are likely due to environment or noise, a study suggests. 
two glowing neuronlike macrophages
Immune Cells Imitating Neurons Cause Pain in Mice with Tumors
Shafaq Zia | Oct 18, 2022 | 3 min read
Whether the finding of a novel mechanism for cancer-related pain can lead to better treatments for neuropathic pain in people remains to be seen.
Identifying Biomarkers to Guide Cancer Immunotherapy
Identifying Biomarkers to Guide Cancer Immunotherapy
The Scientist | 2 min read
An expert panel will discuss the cutting-edge technologies they used to identify novel biomarkers that predict patient responses to immunotherapy.
Illustration of intestine containing pink microbes
Fungal DNA, Cells Found in Human Tumors
Catherine Offord | Sep 30, 2022 | 2 min read
It’s not clear whether, or how, the organisms might play a role in disease pathology.
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