Illustration of microbes in gut
Fungal DNA, Cells Found in Human Tumors
It’s not clear whether, or how, the organisms might play a role in disease pathology.
Fungal DNA, Cells Found in Human Tumors
Fungal DNA, Cells Found in Human Tumors

It’s not clear whether, or how, the organisms might play a role in disease pathology.

It’s not clear whether, or how, the organisms might play a role in disease pathology.

tumor
Histological slide showing cancerous prostate tissue
2D Genetic Map of Prostate Cells Charts Cancer Growth
Holly Barker | Aug 23, 2022
An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.
Photograph of Humsa Venkatesh
Humsa Venkatesh Probes Cancer’s Grip on the Brain
Maddie Bender | Aug 15, 2022
At Brigham and Women’s Hospital, the cancer biologist is combining research into the tumor microenvironment with the principles of neuroscience to tease apart how cancers grow—and how to stop them.
Overcoming T Cell Therapy Barriers with Engineered Proteins
Overcoming T Cell Therapy Barriers with Engineered Proteins
The Scientist Creative Services Team
Shannon Oda will discuss how to develop novel engineered fusion proteins to improve T cell therapies against hematological and solid tumors.
black-and-white brain scan showing tumor
Glioblastoma Cells Imitate Immature Neurons to Invade the Brain
Sophie Fessl | Aug 5, 2022
Neuron-like glioblastoma cells are the pioneers of deadly tumors’ spread through the brain, contributing to their devastating invasiveness, a study in mice finds.
salmonella bacteria 3d illustration
Salmonella Injection Helps the Mouse Immune System Kill Tumors
Dan Robitzski | May 16, 2022
Nanoparticle-coated bacteria can capture tumor antigens and deliver them to immune cells, triggering a response that improved survival rates in mice.
3-D image of a tumor
Cancer Cells Go Incognito to Cause Therapy Relapse
Niki Spahich, PhD
Dormant cancer cells and dysfunctional immune cells living together in a tumor niche form a therapy-resistant reservoir.
Illustration showing how following radiation therapy, which triggers the release of cancer-specific antigens, researchers injected Salmonella typhimurium bacteria covered in positively charged nano- particles near tumors in mice.
Infographic: Salmonella Shuttle Tumor Antigens to Immune Cells
Dan Robitzski | May 16, 2022
Nanoparticle-coated bacteria carry cancer-derived proteins to dendritic cells, enabling the immune system to launch a response in a mouse model.
Diffuse star-like shapes with regions in purple, green, and both colors overlapped.
Tumor Cells on Brink of Death May Trigger Metastasis
Alejandra Manjarrez | Mar 25, 2022
A new study reports that human colon cancer cells at imminent risk of death can instead develop characteristics needed to colonize new parts of the body.
Identifying Biomarkers to Guide Cancer Immunotherapy
Identifying Biomarkers to Guide Cancer Immunotherapy
The Scientist Creative Services Team
An expert panel will discuss the cutting-edge technologies they used to identify novel biomarkers that predict patient responses to immunotherapy.
A stained tissue sample of metastatic pancreatic cancer
Tetanus Immunity Protects Mice Against Pancreatic Cancer
Amanda Heidt | Mar 24, 2022
Because most people are vaccinated against tetanus as children, delivering benign bacteria carrying a tetanus antigen into pancreatic tumors makes them visible to memory cells in the immune system, researchers report.
Tumor microbiome composite
Could Cancer’s Microbiome Help Diagnose and Treat the Disease?
Jef Akst | Mar 14, 2022
A growing appreciation of the bacterial assemblages that live within tumors has researchers striving to understand and capitalize on their role.
Finding CAR T Cells in Solid Tumors by Single-Cell Resolution
Finding CAR T Cells in Solid Tumors at Single-Cell Resolution
The Scientist Creative Services Team in collaboration with Miltenyi Biotec
Rita Pfeifer will discuss visualizing and quantifying CAR T-cell infiltration into solid tumors with 3-D light sheet fluorescence microscopy (LSFM).
Illustration showing microbial signatures of cancer in the body
Infographic: Putting Cancer’s Unique Microbiomes to Use
Jef Akst | Mar 14, 2022
From diagnosis to tracking treatment responses, bacteria and other microbes in the blood, gut, and tumors of cancer patients may provide helpful hints for improving their care.
A photo of a triple-negative breast cancer cell
A Fasting-Mimicking Diet Thwarts Breast Cancer in Mice
Devin A. Reese | Mar 1, 2022
Coupling a diet low in calories, sugar, and protein with existing cancer drugs treats triple-negative breast cancer in mice, and low blood glucose is associated with better cancer outcomes in human patients.
Undone Proteins Take Out Bladder Cancer
Roni Dengler, PhD
An unfolded protein found in human milk shows promise in early clinical trials to treat bladder cancer.
black-and-white image of an open mouth
The Common Mouth Microbe That Keeps Popping Up in Tumors
David Adam | Dec 15, 2021
Lab studies link the oral bacteria Fusobacterium nucleatum to cancers from the gut to the head and neck. Could targeting the microbe tackle tumors?
A compilation of several images, including a dog, a blind mole rat, and cell micrographs
Our Favorite Cancer Stories of 2021
Amanda Heidt | Dec 9, 2021
This year revealed just how much scientists have learned about the disease, from how animals become naturally cancer-resistant to how tumor cells harness extracellular DNA to develop rapid drug resistance.
Advancing Cancer Biomarker Detection with Single Cell Proteomics
The Scientist Creative Services Team in Collaboration with IsoPlexis
An improved ELISA-based proteomics chip detects cytokines in single cell applications.
fingertips with pills on them
Over-the-Counter Antihistamines Could Help Against Cancer
Alejandra Manjarrez | Nov 24, 2021
The binding of histamine with one of its receptors within the tumor environment makes cancer cells more resistant to immunotherapy, according to a new study. Blocking that binding could improve responses to treatment.