T Cell–Boosting Zika Vaccine Protects Mice from the Virus
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
T Cell–Boosting Zika Vaccine Protects Mice from the Virus

By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.

By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.

zika
Transforming Virology Research with Cryo-EM
Transforming Virology Research with Cryo-EM
The Scientist Creative Services Team | May 11, 2021
Explore what researchers can do with Cryo-EM
First US Field Test of GM Mosquitoes Begins in Florida
First US Field Test of GM Mosquitoes Begins in Florida
Christie Wilcox | May 4, 2021
After years of push back, the first batch of Oxitec’s engineered mosquitoes, designed to reduce population numbers, have been released in the Keys.
Mosquitos in Asia and the Americas More Susceptible to Zika Virus
Mosquitos in Asia and the Americas More Susceptible to Zika Virus
Abby Olena | Nov 19, 2020
A study explains how Zika was present among mosquitoes in Africa for decades without causing the harm to human health seen outside the continent in recent years.
Zika Infection Increases Risk of Severe Dengue Fever
Zika Infection Increases Risk of Severe Dengue Fever
Ruth Williams | Aug 27, 2020
A study of Nicaraguan children links prior Zika virus infection with aggravated dengue fever symptoms.
750 Million GM Mosquitoes Will Be Released in the Florida Keys
750 Million GM Mosquitoes Will Be Released in the Florida Keys
Lisa Winter | Aug 21, 2020
There have been no reports of health or environmental harm in other locations where genetically modified mosquitoes have been introduced over the last decade.
Did Contaminated Water Exacerbate Brazilian Babies’ Zika Symptoms?
Did Contaminated Water Exacerbate Brazilian Babies’ Zika Symptoms?
Ashley Yeager | Jun 1, 2020
Elevated levels of a neurotoxin in northeastern Brazil’s drinking water and a high incidence of microcephaly in the region led scientists to look for a link, and they found one.
Zika as Cancer Buster?
Zika as Cancer Buster?
Amy Schleunes | Apr 1, 2020
By infecting glioblastoma cells but not healthy brain tissue, some form of the virus could serve a therapeutic purpose.
GM Mosquito Progeny Not Dying in Brazil: Study
GM Mosquito Progeny Not Dying in Brazil: Study
Kerry Grens | Sep 17, 2019
The biotech Oxitec had released the genetically engineered insects with the hope that they would breed with wild populations and produce offspring that die young. But that’s not always happening.
Combination Strategy Nearly Eliminates Invasive Mosquitoes in Field
Combination Strategy Nearly Eliminates Invasive Mosquitoes in Field
Abby Olena | Jul 17, 2019
Researchers use two techniques—Wolbachia infection and irradiation—to suppress reproduction in populations of Asian tiger mosquitoes at two study sites in China.
MIT Researcher Allegedly Copied Other Groups’ Drug Designs
MIT Researcher Allegedly Copied Other Groups’ Drug Designs
Catherine Offord | May 29, 2019
Executives at a biotech that develops new antibodies argue that Ram Sasisekharan didn’t come up with the structures for at least two experimental therapies that his group has described.
Does Prior Dengue Exposure Help or Hurt a Zika Infection?
Does Prior Dengue Exposure Help or Hurt a Zika Infection?
Diana Kwon | Mar 6, 2019
Animal and cell culture studies show evidence that dengue antibodies can both neutralize and enhance Zika, but human investigations have only found protective effects.
Past Dengue Infection Appears to Protect Children from Zika Symptoms
Past Dengue Infection Appears to Protect Children from Zika Symptoms
Carolyn Wilke | Jan 23, 2019
Children were 38 percent less likely to show signs of Zika infection if they had previously had dengue.
Photos of the Year
Photos of the Year
Carolyn Wilke | Dec 21, 2018
From 500-million-year-old fat to a newly discovered virus, here are some stunners from The Scientist in 2018.
Zika Likes it Warmer than Dengue: Study
Zika Likes it Warmer than Dengue: Study
Anna Azvolinsky | Aug 15, 2018
Climate change may open up new habitats suitable for the virus’s spread.
Zika’s Effects on Babies Can Show Up Later
Zika’s Effects on Babies Can Show Up Later
Kerry Grens | Aug 7, 2018
The CDC finds one in seven children exposed to the virus in utero experiences health problems by age one.
Predicting Future Zoonotic Disease Outbreaks
Predicting Future Zoonotic Disease Outbreaks
Ashley Yeager | Jun 1, 2018
A step-by-step study of diseases that jump species gives subtle clues about future epidemics.
Postnatal Zika Infection Causes Brain Damage in Infant Macaques
Postnatal Zika Infection Causes Brain Damage in Infant Macaques
Jim Daley | Apr 4, 2018
The findings highlight the need for long-term monitoring of children exposed to the virus, say scientists. 
Antibiotics Increase Mouse Susceptibility to Dengue, West Nile, and Zika
Antibiotics Increase Mouse Susceptibility to Dengue, West Nile, and Zika
Shawna Williams | Mar 27, 2018
The drugs’ disruption of the microbiome makes a subsequent flavivirus infection more severe.
Parts of U.S. Saw an Increase in Zika-Linked Birth Defects in 2016
Parts of U.S. Saw an Increase in Zika-Linked Birth Defects in 2016
Katarina Zimmer | Jan 26, 2018
The rise occurred in areas with confirmed local transmission, according to a new CDC report.