Technique Talk: Understanding Cancer One Base Edit at a Time

Francisco J. Sánchez-Rivera will discuss strategies to design CRISPR base editor libraries for in vivo applications.

Event Details:Technique Talk: Understanding Cancer One Base Edit at a TimeDate(s):

This webinar will be hosted live and available on-demand

Monday, June 20th, 2022
10:00 - 11:00 AM Eastern Time

Single nucleotide variants (SNVs) shape cellular phenotypes and disease susceptibility in cancer. To investigate the functional consequences of SNVs, scientists use single nucleotide CRISPR base editors to make precise genetic changes.

In this Technique Talk, Francisco J. Sánchez-Rivera will discuss how to develop base editor sensor libraries for the high-throughput analysis of causative variants in preclinical cancer models.

Learning Objectives

How to engineer and manipulate single nucleotide bases with precision in cells and organisms
How single nucleotide changes influence cancer initiation and progression

Enroll Now

Meet the Instructor:

Francisco J. Sánchez-Rivera, PhD
Assistant Professor
Department of Biology
Koch Institute for Integrative Cancer Research
MIT

TSU Sponsored By

Keywords

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue

Research Resources

Podcasts

Webinars

Videos

Infographics

eBooks

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

In this webinar, Nathan Sepulveda will share how to specifically and reproducibly measure residual HEK293 DNA during biotherapeutic product development.

How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Today’s thermocyclers are more intuitive and flexible, letting scientists focus on their experiments rather than their instruments.

Characterizing Immune Memory to COVID-19 Vaccination

In this webinar, Alex George will discuss how he used high-dimensional single-cell profiling to analyze immune memory to COVID-19 vaccines in human samples.

Optimize PCR assays with true linear temperature gradients

Applied Biosystems™ VeriFlex™ System: True Temperature Control for PCR Protocols

A new thermocycler technology helps scientists optimize reactions with six different settable temperature zones for better control and linear gradients.

Products

Product News

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Long-lasting, bright F-actin staining made easy with Biotium's new ActinBrite™ High Affinity Phalloidin Conjugates.

Latest AI software simplifies image analysis and speeds up insights for scientists

The Aivia 15 release includes deep learning-powered tools for 2D and 3D cell segmentation.

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

The integrated solution enables parallel high-resolution analysis of hundreds to thousands of individual cells, addressing growing demand for scalable, multiomics approaches in single-cell research.

Agilent BioTek Cytation C10 Confocal Imaging Reader

From confocal, widefield, and live cell imaging to multimode reading, the Agilent BioTek Cytation C10 confocal imaging reader delivers crisp, high-resolution images and the ability to image and analyze 3D samples.