The Scientist Speaks

Lukas Chavez uses multiomic techniques to study how extrachromosomal DNA (ecDNA) contributes to tumor heterogeneity and gene expression changes in medulloblastoma.

Researchers tackle the antibiotic resistance crisis with explainable neural networks and high throughput drug discovery.

Researchers explore the trippy science behind natural hallucinogens in humans. 

Jonathan Weissman and Luke Gilbert share how they developed several CRISPR-based epigenetic editors and how these tools differ from traditional CRISPR.

Scientists discuss the advent of robotically run research and the new era of academic cloud labs on the horizon.

Researchers get creative using bacterial bits and pieces to produce synthetic cells for studying cancer.

Fecal transplants may help scientists improve current treatment strategies for anorexia nervosa.

Researchers turn to unique eukaryotes to better understand how DNA is organized in 3D space.

Filling in the gaps about the genetic risk factors of stuttering may help scientists shatter stigmas and discover new therapies.

Understanding the role of immune cells in neurodegeneration may help scientists develop new diagnostic, prognostic, and treatment tools.

Tricking the body into mimicking a fasting state may hold the key to fighting age-related cognitive decline. 

Vera Gorbunova discusses what naked and blind mole-rat cells reveal about aging and cancer resistance mechanisms. 

Neelanjan Mukherjee discusses how RNA decay is essential for regulating a blood pressure-controlling hormone.

Karen Miga discusses how she and collaborators sequenced the missing parts of the human genome almost two decades after the first Human Genome Project published its results.

Heather Kittredge and Sarah Evans discuss the environmental conditions that facilitate natural transformation in bacteria’s native habitat.  

Anthony Richardson discusses what makes Staph especially dangerous for people with diabetes.

Patrick Wilson discusses the challenges in designing universal vaccines and his work developing one for influenza.

Maya Kaelberer discusses her research investigating how sensory cells in the gut guide feeding behavior.

Don Ingber discusses how organ-on-a-chip technology helps identify, study, and combat viral variants that could cause the next pandemic.