Week in Review, June 17–21

On the gene patent decision; a high-res human brain model; bats’ influence on moths mating calls; toxicants threaten brain health; platelet-driven immunity

Written byJef Akst
| 4 min read

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WIKIMEDIA, MIKE MITCHELL, NCILast Thursday (June 13), the Supreme Court of the United States unanimously ruled against the patentability of isolated human genes, such as the patents Myriad Genetics held on two BRCA genes, mutations in which are linked to breast and ovarian cancer. In an essay (published early online as a result of the High Court’s decision) for our July print issue, lawyer Joan Ellis of the Dickinson Wright firm wrote that the finding is not surprising, and lays out the precedent set by previous Supreme Court cases. And while many have raised concerns about what the invalidated patents will mean for the biotech and pharma industries looking to get healthy returns on investment in the genetic testing field, Jeffery Perkel reported that many will actually benefit from the decision.

Women at high risk for breast and ovarian cancer will now likely have more than one option for a genetic test before deciding whether or not to receive a mastectomy or ovariectomy; healthcare consumers should see the costs of genetic diagnostics drop as more competition enters the marketplace; and researchers previously weary of venturing into the genetic testing field can now forge ahead without fear of litigation. “I am delighted,” Mary-Claire King of the University of Washington School of Medicine told the New Scientist last week. “This is a fabulous result for patients, physicians, scientists, and common sense.”

AMUNTS, ET AL.More than 7,400 20-µm-thick slices of human brain tissue have been painstakingly stitched together into the most in-depth model of the organ ever built, exceeding the resolution of previous models “by a factor of 50 in each direction,” study leader Katrin Amunts of the Jülich Aachen Research Alliance in Germany, told The Scientist.

The so-called ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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