The Scientist - Home

Faced with a lack of consensus in published protocols, researchers found optimal conditions for enhancing cortical neuron adhesion and maturation in culture.

Microbiome studies have yielded hundreds of ideas for ways to detect and influence human health, but the field struggles with reproducibility challenges that hamper bringing these goals to fruition. Identical tubes of fecal matter should help.

Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks.

A special type of immune cell aids digestion of chitin, a fiber found in mushrooms and insects.

Endometrial organoids and single cell analyses helped uncover the molecular mechanisms of a rare uterine condition.

New technologies and archival tissue biopsy samples enable exploration of changes in the bone marrow as people age.

A state-of-the-art technique helps scientists map out tissue at the single cell level after a demyelinating brain injury.

A risk-benefit analysis of gene editing tools in stem cells revealed that base and prime editing carry vulnerabilities similar to those of CRISPR-Cas9, but at a reduced rate. 

Researchers ingeniously repurposed DNA to assemble a miniaturized blaster at the molecular level.

Researchers generated complete genomes of two important bat species and explored their immune- and cancer-related genes.

Fossilized feces help scientists understand the lives of Puerto Rico’s earliest inhabitants.

Cell adhesion may be initiated by small proteins previously viewed as helpers, not main players in attachment.